Dental hygiene pharmacology national
board questions with answers
What is the therapeutic range on a log dose effect curve ✅✅Where the dose is
increasing sharply
On a log dose effect curve where is the maximum response ✅✅Where the curve
plateaus
What is potency ✅✅The amount of a drug needed to produce an effect
What is efficacy ✅✅The maximum effect that a drug can have regardless of the dose.
Once reached delivering more of the drug will not add effects
Efficacy and potency are unrelated. ✅✅...
Enteral drug administration is what ✅✅Placed directly into GI tract. This is done by
taking the drug orally, rectally
What is parenteral administration of a drug ✅✅Injection
What is the most cost effective and safest way to take a drug ✅✅Orally
What can happen is a drug tHat is made from proteins is taken orally ✅✅The acidity
of the GI tract can be inactivated. ex. Insulin can not be taken orally
What is the first pass effect ✅✅When a drug passes through the hepatic portal
circulation. Some of the active ingredients can be inactivated.
This may decrease some of the available drugs that can be activated.
What happens when a drug has a high first pass effect. ✅✅They require a larger
dose.
How are the phase one reactions carried out in the liver ✅✅By microsomal or
cytochrome p450 enzymes
Alcohol tolerance is a common example
When would you want to administer a drug rectally ✅✅When a person is unconscious
or vomiting
, What are the different types of parenteral drug administrations ✅✅Intra vascular
Intramuscular
Subcutaneous
Intradermal
Inhalation
Topical
What are some characteristics of the intra vascular parenteral route ✅✅Absorption
phase is bypassed
Most rapid drug response
Drug is really hard to be retrieved
What are some characteristics of intramuscular route parenteral drug admin
✅✅Sustained effect
Usually delivered in the deltoid or gluteals
What are some characteristics of subcutaneous parenteral drug admin ✅✅Best route
to admin protein products
May produce a sterile access or a hematoma
Insulin, anesthesia
What are some characteristics of the intra dermal parenteral route ✅✅Injected in the
epidermis
Like the tuberculosis test
What are so e characteristics of the inhalation route ✅✅Provides rapid delivery
Asthma and nitrous
What are some characteristics of the topical route ✅✅Do not use if site is ulcerated or
burned
Usually has a increased concentration
What is pharmakinetics ✅✅How a drug is administered , distributed, metabolized and
excreted.
What can lipid solvable drugs do ✅✅Cross the blood brain barrier
Can move across most biological barriers
In regards to drug distribution where does the doses go ✅✅Oral goes to liver
Sublingual goes to heart
What happens if the drug binds to protein ✅✅Increase the dose
What is the main site for drug metabolism ✅✅The liver
board questions with answers
What is the therapeutic range on a log dose effect curve ✅✅Where the dose is
increasing sharply
On a log dose effect curve where is the maximum response ✅✅Where the curve
plateaus
What is potency ✅✅The amount of a drug needed to produce an effect
What is efficacy ✅✅The maximum effect that a drug can have regardless of the dose.
Once reached delivering more of the drug will not add effects
Efficacy and potency are unrelated. ✅✅...
Enteral drug administration is what ✅✅Placed directly into GI tract. This is done by
taking the drug orally, rectally
What is parenteral administration of a drug ✅✅Injection
What is the most cost effective and safest way to take a drug ✅✅Orally
What can happen is a drug tHat is made from proteins is taken orally ✅✅The acidity
of the GI tract can be inactivated. ex. Insulin can not be taken orally
What is the first pass effect ✅✅When a drug passes through the hepatic portal
circulation. Some of the active ingredients can be inactivated.
This may decrease some of the available drugs that can be activated.
What happens when a drug has a high first pass effect. ✅✅They require a larger
dose.
How are the phase one reactions carried out in the liver ✅✅By microsomal or
cytochrome p450 enzymes
Alcohol tolerance is a common example
When would you want to administer a drug rectally ✅✅When a person is unconscious
or vomiting
, What are the different types of parenteral drug administrations ✅✅Intra vascular
Intramuscular
Subcutaneous
Intradermal
Inhalation
Topical
What are some characteristics of the intra vascular parenteral route ✅✅Absorption
phase is bypassed
Most rapid drug response
Drug is really hard to be retrieved
What are some characteristics of intramuscular route parenteral drug admin
✅✅Sustained effect
Usually delivered in the deltoid or gluteals
What are some characteristics of subcutaneous parenteral drug admin ✅✅Best route
to admin protein products
May produce a sterile access or a hematoma
Insulin, anesthesia
What are some characteristics of the intra dermal parenteral route ✅✅Injected in the
epidermis
Like the tuberculosis test
What are so e characteristics of the inhalation route ✅✅Provides rapid delivery
Asthma and nitrous
What are some characteristics of the topical route ✅✅Do not use if site is ulcerated or
burned
Usually has a increased concentration
What is pharmakinetics ✅✅How a drug is administered , distributed, metabolized and
excreted.
What can lipid solvable drugs do ✅✅Cross the blood brain barrier
Can move across most biological barriers
In regards to drug distribution where does the doses go ✅✅Oral goes to liver
Sublingual goes to heart
What happens if the drug binds to protein ✅✅Increase the dose
What is the main site for drug metabolism ✅✅The liver
