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Nurs 660 Exam 1- Antipsychotic Medications with accurate solutions

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Nurs 660 Exam 1- Antipsychotic Medications with accurate solutions

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Nurs 660 Exam 1- |! |! |! |!




Antipsychotic Medications |! |!




with accurate solutions |! |!




Three classes of classical/ FGA - Correct answer ✔
|! |! |! |! |! |! |! |!




1) phenothiazines
|!




2) thioxanthenes
|!




3) butyrophenones
|!




prototypical SGA - Correct answer ✔clozapine |! |! |! |! |!




chlorpromazine (THORAZINE) - Correct answer ✔-lowest potentcy |! |! |! |! |! |! |!




antipsychotic |!




-significant alpha-1 adrenergic blockade --> sedation, hypotention
|! |! |! |! |! |!




-DA blockage in basal ganglia --> EPS
|! |! |! |! |! |!




classic example of butyrophenone (FGA) - Correct answer ✔haloperidol
|! |! |! |! |! |! |! |! |!




(HALDOL)



haloperiol (HALDOL) - Correct answer ✔-potent D2 blockade --> acute
|! |! |! |! |! |! |! |! |! |!




treatment of psychosis |! |!




-high EPS, sedation
|! |!

, -less weight gain, anticholinergic effects, hypotension
|! |! |! |! |!




drug usually used to treat acute psychotic episodes - Correct answer
|! |! |! |! |! |! |! |! |! |! |!




✔haloperidol (HALDOL) |!




first generation antipsychotics block what receptors? - Correct answer ✔block
|! |! |! |! |! |! |! |! |!




D2 receptors- therapeutic efficacy correlates with D2 blockade
|! |! |! |! |! |! |! |!




which antipsychotics alleviate mainly positive symptoms, and carry higher
|! |! |! |! |! |! |! |! |!




risk of EPS and tardive dyskinesia with high doses and long-term use -
|! |! |! |! |! |! |! |! |! |! |! |! |!




Correct answer ✔first generation/ typical antipsychotics
|! |! |! |! |!




-haloperidol

-chlorpromazine



SGA have greater affinity for which receptors - Correct answer ✔-affinity for
|! |! |! |! |! |! |! |! |! |! |! |!




serotonin >> dopamine |! |!




SGA characteristics - Correct answer ✔-block more than 1 type of receptor
|! |! |! |! |! |! |! |! |! |! |!




-help positive and negative sxs
|! |! |! |!




-improve cognitive fx |! |!




-less EPS/TD |!




SGA/ atypical (5+) - Correct answer ✔1) clozapine (CLOZARIL)
|! |! |! |! |! |! |! |!




2) risperidone (RIPERDAL)
|! |!

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