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FUNDAMENTALS OF CHEMOTHERAPY
IMMUNOTHERAPY ADMINISTRATION – TEST
2025 BRAND NEW ACTUAL EXAM WITH
ANSWERS.
Monoclonal antibodies - correct answer --lab made antibodies
-mimic antibodies in immune system
Murine - made from mice
Chimeric - part mouse/part human
Humanized - mice antibodies attach human antibodies
Human - fully human antibodies
Rituximab - correct answer --M antibodies (nAbs)
-mixed mice/human
-treat: non-hodgkkins, CLL, RA, granulomatosis, polyangiitis
-IV only
-premed w/ tylenol, benadryl,
-hold HTN meds for previous 12 hrs
Trastuzumab - correct answer -- breast and gastric CA
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-mAb - HUMANIZED
-IV only
- no previous cardiac condition, not pregnant
Angiogenesis - correct answer --blood vessel formation
*tumor angiogenesis - new blood vessels tumors need to grow
-release of chemicals by tumor and by host cells
Antiangiogenic Agents - correct answer --keep new blood vessels
from forming
-prevent growth of new blood vessels tumors need to grow
Bevacizumab - correct answer --colon, lung, glioblastoma, renal,
off label
-mAb- humanized
-IV (do not push), intravitreal (unlabled)
-can cause GI perf, protenuria, fistula, hemorrhage
-do not give 28 days before surgery
Intraperitoneal - correct answer --chemo into abdominal cavity
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-pt changes positions to distribute chemo
Intravesicular - correct answer -chemo delivered directly into
bladder avoiding systemic chemo effects
-through cath
Intrapleural - correct answer -throacotomy tube into pleural lining
-treats some lung CA that produce malignant pleural effusions
Intrathecal/Intraventricular - correct answer -directly into the
cerebrospinal fluid
-prevents/treats CA cells that cant be reached systemically b/c
blood brain barrier
Flare reaction - correct answer -localized allergic reaction along a
vein caused by irritating drugs
Infiltration - correct answer -leaving of IV meds into the
surrounding tissue
FUNDAMENTALS OF CHEMOTHERAPY
IMMUNOTHERAPY ADMINISTRATION – TEST
2025 BRAND NEW ACTUAL EXAM WITH
ANSWERS.
Monoclonal antibodies - correct answer --lab made antibodies
-mimic antibodies in immune system
Murine - made from mice
Chimeric - part mouse/part human
Humanized - mice antibodies attach human antibodies
Human - fully human antibodies
Rituximab - correct answer --M antibodies (nAbs)
-mixed mice/human
-treat: non-hodgkkins, CLL, RA, granulomatosis, polyangiitis
-IV only
-premed w/ tylenol, benadryl,
-hold HTN meds for previous 12 hrs
Trastuzumab - correct answer -- breast and gastric CA
, Page | 2
-mAb - HUMANIZED
-IV only
- no previous cardiac condition, not pregnant
Angiogenesis - correct answer --blood vessel formation
*tumor angiogenesis - new blood vessels tumors need to grow
-release of chemicals by tumor and by host cells
Antiangiogenic Agents - correct answer --keep new blood vessels
from forming
-prevent growth of new blood vessels tumors need to grow
Bevacizumab - correct answer --colon, lung, glioblastoma, renal,
off label
-mAb- humanized
-IV (do not push), intravitreal (unlabled)
-can cause GI perf, protenuria, fistula, hemorrhage
-do not give 28 days before surgery
Intraperitoneal - correct answer --chemo into abdominal cavity
, Page | 3
-pt changes positions to distribute chemo
Intravesicular - correct answer -chemo delivered directly into
bladder avoiding systemic chemo effects
-through cath
Intrapleural - correct answer -throacotomy tube into pleural lining
-treats some lung CA that produce malignant pleural effusions
Intrathecal/Intraventricular - correct answer -directly into the
cerebrospinal fluid
-prevents/treats CA cells that cant be reached systemically b/c
blood brain barrier
Flare reaction - correct answer -localized allergic reaction along a
vein caused by irritating drugs
Infiltration - correct answer -leaving of IV meds into the
surrounding tissue
