ONS/ONCC CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATION ACTUAL EXAM 200+ QUESTIONS WITH DETAILED VERIFIED ANSWERS 100% CORRECT ALREADY GRADED A+ LATEST VERSION

ONS/ONCC CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATION ACTUAL EXAM 200+ QUESTIONS WITH DETAILED VERIFIED ANSWERS 100% CORRECT ALREADY GRADED A+ LATEST VERSION "The 2 most important neurotransmitters involved in vomiting are: - CORRECT ANSWER= 1. Serotonin 2. Substance P" "Describe the peripheral pathway of CINV - CORRECT ANSWER= Primarily occurs in the GI tract Associated with acute CINV Neurotransmitter -- serotonin" "Describe the central pathway of CINV - CORRECT ANSWER= Primarily occurs in the brain Associated with delayed CINV Neurotransmitter -- Substance P" "Common serotonin 5-HT3 antagonists used for CINV: - CORRECT ANSWER= Dolasetron Granisetron Ondansetron Palonosetron" "Common neurokinin-1 antagonists used for CINV: - CORRECT ANSWER= Aprepitant Fosaprepitant" "Common steroids used for CINV: - CORRECT ANSWER= Dexamethasone" "2 types of therapies that commonly have cutaneous reactions: - CORRECT ANSWER= 1. EGFR inhibitor therapies 2. Antimetabolites" "Most-common cutaneous reaction seen with 5-FU and Capecitabine: - CORRECT ANSWER= Palmar-plantar erythrodysesthesia AKA hand-foot syndrome" "Antimetabolites that commonly cause cutaneous reactions: - CORRECT ANSWER= 5-FU Capecitabine (Xeloda)" "Define myelosuppression - CORRECT ANSWER= Bone marrow activity is decreased, resulting in fewer RBCs, WBCs and platelets If severe: myeloablation" "The most common dose-limiting toxicity of chemotherapy - CORRECT ANSWER= Myelosuppression" "Define nadir, and when does it occur? - CORRECT ANSWER= The point at which blood cell counts are at their lowest following a treatment cycle. Typically occurs 7-10 days following cycle" "NCCN defines neutropenia as an ANC _______/mm^3 - CORRECT ANSWER= 500" "Risk factors for developing neutropenia include: - CORRECT ANSWER= 65 years old Hx of neutropenia with previous chemotherapy Hx of chemotherapy or radiation treatment Hematologic malignancy Uncontrolled/advanced cancer Lung cancer" "Define neutropenic fever - CORRECT ANSWER= Fever of 101 F or greater one time OR Fever of 100.4 F lasting one hour or longer" "ANC calculation - CORRECT ANSWER= (% polys + % bands) x (WBC)/100" "Normal WBC count - CORRECT ANSWER= 4,500-10,000" "Normal neutrophil count - CORRECT ANSWER= 54%-62% of WBC" "An ANC of less that _____ is considered a risk for infection - CORRECT ANSWER= 1,000" "Define thrombocytopenia - CORRECT ANSWER= Low platelet count" "Symptoms of thrombocytopenia - CORRECT ANSWER= Petechiae or easily bruising Headaches Hypotension and tachycardia Prolonged bleeding (gums, menstruation)" "Define anemia - CORRECT ANSWER= Deficiency of RBC or hemoglobin in the blood" "Symptoms of anemia - CORRECT ANSWER= Dyspnea Fatigue Dizziness Headaches" "Acute diarrhea lasts: - CORRECT ANSWER= 1-2 days and resolves on its own" "Persistent diarrhea lasts: - CORRECT ANSWER= 2-4 weeks" "Chronic diarrhea lasts: - CORRECT ANSWER= 4 weeks"