BIO 252 FINAL EXAM STUDY GUIDE
Chapter 10:
A. Muscle tissue function
Produce body movements
Stabilized body positions
Storing and moving substances
Generates heat
B. Types of skeletal muscle proteins/function (p.300)
Contractile Proteins ( generates force during contraction)
Myosin: Makes up the thick filaments, consist of a tail and two myosin heads
which binds to myosin binding site on acting molecule during contraction.
Actin: Protein that is the main component of thin filament, each actin molecule
has myosin –binding site, where myosis head of thick filament binds during
contraction
Regulatory Proteins (help switch muscle contraction on and off)
Troponin. Component of thin filament, when calcium ions binds to troponin, it
changes shape, this change moves tropomyosin away from myosin-binding on
actin molecules
Tropomyosin; Component of thin filament, when skeleton muscle fiber relaxed,
tropomyosin covers myosin binding sites on actin molecules, preventing myosin
from binding to actin.
Structural Proteins; Keep thin and thick filaments of myofibrils in proper
alignment
Titin;Structure protein that connects z discs to M line of sarcomere helping to
stabilize thick filaments positions, can stretch and spring back unharmed
Dystrophin; Connects to the membrane protein
Chapter 11:
A. Steps in skeletal muscle contraction
1. Calcium binds to troponin, rotating tromyosin off the active site on actinng
2. Cross bridging occurs between the active site on the actin and myosin head.
1
Chapter 10:
A. Muscle tissue function
Produce body movements
Stabilized body positions
Storing and moving substances
Generates heat
B. Types of skeletal muscle proteins/function (p.300)
Contractile Proteins ( generates force during contraction)
Myosin: Makes up the thick filaments, consist of a tail and two myosin heads
which binds to myosin binding site on acting molecule during contraction.
Actin: Protein that is the main component of thin filament, each actin molecule
has myosin –binding site, where myosis head of thick filament binds during
contraction
Regulatory Proteins (help switch muscle contraction on and off)
Troponin. Component of thin filament, when calcium ions binds to troponin, it
changes shape, this change moves tropomyosin away from myosin-binding on
actin molecules
Tropomyosin; Component of thin filament, when skeleton muscle fiber relaxed,
tropomyosin covers myosin binding sites on actin molecules, preventing myosin
from binding to actin.
Structural Proteins; Keep thin and thick filaments of myofibrils in proper
alignment
Titin;Structure protein that connects z discs to M line of sarcomere helping to
stabilize thick filaments positions, can stretch and spring back unharmed
Dystrophin; Connects to the membrane protein
Chapter 11:
A. Steps in skeletal muscle contraction
1. Calcium binds to troponin, rotating tromyosin off the active site on actinng
2. Cross bridging occurs between the active site on the actin and myosin head.
1
