,Chapter 01: Introduction to Pathophysiology
d d d d
VanMeter and Hubert: Gould’s Pathophysiology for the Health Professions, 7th Edition
d d d d d d d d d d
MULTIPLE CHOICE d
1. Which of the following would be the most likely cause of an iatrogenic disease? a.
d d d d d d d d d d d d d d An
inherited disorder
d d
b. A combination of specific etiological factors
d d d d d
c. An unwanted effect of a prescribed drug
d d d d d d
d. Prolonged exposure to toxic chemicals in the environment d d d d d d d
ANS: C d
2. The manifestations of a disease are best defined as the
d d d d d d d d d
a. subjective feelings of discomfort during a chronic illness. d d d d d d d
b. signs and symptoms of a disease. d d d d d
c. factors that precipitate an acute episode of a chronic illness.
d d d d d d d d d
d. early indicators of the prodromal stage of infection.
d d d d d d d
ANS: B d
3. The best definition of the term prognosis is the
d d d d d d d d
a. precipitating factors causing an acute episode. d d d d d
b. number of remissions to be expected during the course of a chronic illness.
d d d d d d d d d d d d
c. predicted outcome or likelihood of recovery from a specific disease.
d d d d d d d d d
d. exacerbations occurring during chronic illness. d d d d
ANS: C d
4. Which of the following is considered a systemic sign of disease?
d d d d d d d d d d
a. Swelling of the knee d d d
b. Fever
c. Pain in the neck d d d
d. Red rash on the face d d d d
ANS: B d
5. Etiology is defined as the study of the
d d d d d d d
a. causes of a disease. d d d
b. course of a disease. d d d
c. expected complications of a disease. d d d d
d. manifestations of a disease. d d d
ANS: A d
6. A type of cellular adaptation in which there is a decrease in cell size is referred to as a.
d d d d d d d d d d d d d d d d d d
hypertrophy. d
b. metaplasia.
c. anaplasia.
d. atrophy.
, ANS: D d
7. A change in a tissue marked by cells that vary in size and shape and show increased
d d d d d d d d d d d d d d d d
mitotic figures would be called
d d d d d
a. metaplasia.
b. atrophy.
c. dysplasia.
d. hypertrophy.
ANS: C d
8. A deficit of oxygen in the cells usually due to respiratory or circulatory problems is called a.
d d d d d d d d d d d d d d d d
apoptosis.
d
b. ischemia.
c. hypertrophy.
d. necrosis.
ANS: B d
9. When a group of cells in the body dies, the change is called
d d d d d d d d d d d d
a. ischemia.
b. gangrene.
c. hypoxia.
d. necrosis.
ANS: D d
10. Rigorous weightlifting/body building regimens may result in the skeletal muscle cells
d d d d d d d d d d
undergoing a. hypertrophy.
d d
b. dysplasia.
c. atrophy.
d. regeneration.
ANS: A d
11. The term cancer refers to
d d d d
a. dysplasia.
b. hyperplasia.
c. metaplasia.
d. malignant neoplasm. d
ANS: D d
12. To which of the following does the term apoptosis refer?
d d d d d d d d d
a. Increased rate of mitosis by certain cells d d d d d d
b. Ischemic damage to cells d d d
, c. Liquefaction of necrotic tissue d d d
d. Preprogrammed cell self-destruction d d
ANS: D d
13. Which of the following statements is TRUE?
d d d d d d
a. Alteration of DNA does not change cell function. d d d d d d d
b. Damaged cells may be able to repair themselves. d d d d d d d
c. All types of cells die at the same rate.
d d d d d d d d
d. Mild ischemia causes immediate cell death.
d d d d d
ANS: B d
14. Caseation necrosis refers to an area where
d d d d d d
a. cell proteins have been denatured.
d d d d
b. cells are liquefied by enzymes.
d d d d
c. dead cells form a thick cheesy substance.
d d d d d d
d. bacterial invasion has occurred. d d d
ANS: C d
15. Routine application of sun block to skin would be an example of
d d d d d d d d d d d
a. an iatrogenic cause of cancer.
d d d d
b. a preventive measure.
d d
c. a precipitating factor.
d d
d. a predisposing condition.
d d
ANS: B d
16. A circumstance that causes a sudden acute episode of a chronic disease to occur is termed
d d d d d d d d d d d d d d d
a. latent stage. d
b. predisposing factor. d
c. incidence.
d. precipitating factor. ANS: D d d d
17. The term homeostasis refers to
d d d d
a. the causative factors in a particular disease.
d d d d d d
b. maintenance of a stable internal environment. d d d d d
c. a condition that triggers an acute episode.
d d d d d d
d. a collection of signs and symptoms.
d d d d d
ANS: B d
18. Which term is used to describe a new and secondary or additional problem that arises after
d d d d d d d d d d d d d d d
the original disease has been established?
d d d d d d
a. Symptoms
b. Occurrence
c. Manifestations
d. Complication
ANS: D d
19. Pathophysiology involves the study of d d d d
d d d d
VanMeter and Hubert: Gould’s Pathophysiology for the Health Professions, 7th Edition
d d d d d d d d d d
MULTIPLE CHOICE d
1. Which of the following would be the most likely cause of an iatrogenic disease? a.
d d d d d d d d d d d d d d An
inherited disorder
d d
b. A combination of specific etiological factors
d d d d d
c. An unwanted effect of a prescribed drug
d d d d d d
d. Prolonged exposure to toxic chemicals in the environment d d d d d d d
ANS: C d
2. The manifestations of a disease are best defined as the
d d d d d d d d d
a. subjective feelings of discomfort during a chronic illness. d d d d d d d
b. signs and symptoms of a disease. d d d d d
c. factors that precipitate an acute episode of a chronic illness.
d d d d d d d d d
d. early indicators of the prodromal stage of infection.
d d d d d d d
ANS: B d
3. The best definition of the term prognosis is the
d d d d d d d d
a. precipitating factors causing an acute episode. d d d d d
b. number of remissions to be expected during the course of a chronic illness.
d d d d d d d d d d d d
c. predicted outcome or likelihood of recovery from a specific disease.
d d d d d d d d d
d. exacerbations occurring during chronic illness. d d d d
ANS: C d
4. Which of the following is considered a systemic sign of disease?
d d d d d d d d d d
a. Swelling of the knee d d d
b. Fever
c. Pain in the neck d d d
d. Red rash on the face d d d d
ANS: B d
5. Etiology is defined as the study of the
d d d d d d d
a. causes of a disease. d d d
b. course of a disease. d d d
c. expected complications of a disease. d d d d
d. manifestations of a disease. d d d
ANS: A d
6. A type of cellular adaptation in which there is a decrease in cell size is referred to as a.
d d d d d d d d d d d d d d d d d d
hypertrophy. d
b. metaplasia.
c. anaplasia.
d. atrophy.
, ANS: D d
7. A change in a tissue marked by cells that vary in size and shape and show increased
d d d d d d d d d d d d d d d d
mitotic figures would be called
d d d d d
a. metaplasia.
b. atrophy.
c. dysplasia.
d. hypertrophy.
ANS: C d
8. A deficit of oxygen in the cells usually due to respiratory or circulatory problems is called a.
d d d d d d d d d d d d d d d d
apoptosis.
d
b. ischemia.
c. hypertrophy.
d. necrosis.
ANS: B d
9. When a group of cells in the body dies, the change is called
d d d d d d d d d d d d
a. ischemia.
b. gangrene.
c. hypoxia.
d. necrosis.
ANS: D d
10. Rigorous weightlifting/body building regimens may result in the skeletal muscle cells
d d d d d d d d d d
undergoing a. hypertrophy.
d d
b. dysplasia.
c. atrophy.
d. regeneration.
ANS: A d
11. The term cancer refers to
d d d d
a. dysplasia.
b. hyperplasia.
c. metaplasia.
d. malignant neoplasm. d
ANS: D d
12. To which of the following does the term apoptosis refer?
d d d d d d d d d
a. Increased rate of mitosis by certain cells d d d d d d
b. Ischemic damage to cells d d d
, c. Liquefaction of necrotic tissue d d d
d. Preprogrammed cell self-destruction d d
ANS: D d
13. Which of the following statements is TRUE?
d d d d d d
a. Alteration of DNA does not change cell function. d d d d d d d
b. Damaged cells may be able to repair themselves. d d d d d d d
c. All types of cells die at the same rate.
d d d d d d d d
d. Mild ischemia causes immediate cell death.
d d d d d
ANS: B d
14. Caseation necrosis refers to an area where
d d d d d d
a. cell proteins have been denatured.
d d d d
b. cells are liquefied by enzymes.
d d d d
c. dead cells form a thick cheesy substance.
d d d d d d
d. bacterial invasion has occurred. d d d
ANS: C d
15. Routine application of sun block to skin would be an example of
d d d d d d d d d d d
a. an iatrogenic cause of cancer.
d d d d
b. a preventive measure.
d d
c. a precipitating factor.
d d
d. a predisposing condition.
d d
ANS: B d
16. A circumstance that causes a sudden acute episode of a chronic disease to occur is termed
d d d d d d d d d d d d d d d
a. latent stage. d
b. predisposing factor. d
c. incidence.
d. precipitating factor. ANS: D d d d
17. The term homeostasis refers to
d d d d
a. the causative factors in a particular disease.
d d d d d d
b. maintenance of a stable internal environment. d d d d d
c. a condition that triggers an acute episode.
d d d d d d
d. a collection of signs and symptoms.
d d d d d
ANS: B d
18. Which term is used to describe a new and secondary or additional problem that arises after
d d d d d d d d d d d d d d d
the original disease has been established?
d d d d d d
a. Symptoms
b. Occurrence
c. Manifestations
d. Complication
ANS: D d
19. Pathophysiology involves the study of d d d d
