GMS 6504 MODULE 1-3 Exam 1 Questions With Correct Answers

GMS 6504 MODULE 1-
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3
Exam
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1 Questions With Correct Answers
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What
/are /System /Independent /Parameters? /- /correct /answer(s) /✔✔ /Affinity



Efficacy



What
/are


/the


/parts


/of /


a
/system


/that


/are


/identified


/as


/System


/Dependent /Parameters? /- /correct /answer(s) /✔✔ /Number /of /receptors



Cellular /machinery /

Presence /of /other /drugs /

- /Competitive /

- /Noncompetitive



Affinity
/is /-

,/correct
/answer(s) /✔✔ /Thermokinetic /propensity /of /drug /to /bind /to /receptor /




Based /largely /on /ΔG



Efficacy
/is /-


/correct


/answer(s)


/✔✔


/Magnitude /of /change /of /receptor /shape/function /upon /drug /binding /




Based /on /atom/atom /interactions



What
/is


/the


/Occupancy


/Theory? /-


/correct


/answer(s)


/✔✔


/Response /is /proportional /to /fraction /of /receptors /that /are /occupied




100% /response /is /obtained /when /all /receptors /have /ligand



What /formula /do /we /use /to /predict /occupancy? /- /correct /answer(s) /✔✔
/Langmuir /equation



DR/Rt /= /r /= /D/D+Kd



How /do /we /define /response /effect? /- /correct /answer(s) /✔✔ /A+R /--
> /(AR)

, Intrinsic /activity /is /depicted /as /what /letter?

How /is /it /defined? /- /correct /answer(s) /✔✔ /Alpha



Multiplication
/factor /describing /ability /of /agonist /to /produce /a /stimulus




In /terms /of /intrinsic /activity, /what /is /determined /to /be /a /full /agonist? /-
/correct /answer(s) /✔✔ /α /= /1




In
/terms


/of


/intrinsic


/activity,


/what


/is


/determined /to /me /a /partial /agonist? /- /correct /answer(s) /✔✔ /0 /< /α /< /1




In
/terms


/of /intrinsic /activity, /what /is /determined /to /be /an /antagonist? /- /correct


/answer(s) /✔✔ /α /= /0




What
/is


/the


/formula


/for


/the /estimation /of /relative /efficacy? /- /correct /answer(s) /✔✔ /R /= /f /( /α /x /r


/x /Rt /)




f /= /stimulus /response /