MODULE 4 EXAM
Actual Questions and Verified Answers
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Portage Learning, Geneva College
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Updated Module 4 Exam
True & False Questions
Multiple Choice Questions and Answers
Expert-Verified Explanations
,### Ques on 1
The coagula on cascade involves each of the following except:
- Make thrombocytes
Verified Explana on:
The coagula on cascade is responsible for the conversion of soluble plasma
proteins into an insoluble fibrin clot. It includes ac va on of intrinsic and extrinsic
pathways, conversion of prothrombin to thrombin, and fibrinogen to fibrin.
Thrombocyte (platelet) forma on is a process called thrombopoiesis, primarily
taking place in the bone marrow, and is not a direct func on of the coagula on
cascade.
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Which of the following increases the chance of clo ng? Select all that apply.
- Protein C deficiency
Verified Explana on:
Protein C is a natural an coagulant that degrades factors Va and VIIIa. Its
deficiency results in a loss of inhibitory control of the coagula on cascade, thus
increasing clo*ng risk. In contrast, vitamin K deficiency, vWF deficiency, and
thrombocytopenia impair coagula on and increase bleeding risk.
,---
The three stages of hemostasis include each of the following except:
- Vascular dila on
Verified Explana on:
Hemostasis refers to the cessa on of bleeding and consists of: (1) vascular
constric on, (2) forma on of a platelet plug, and (3) blood coagula on. Vascular
dila on is not a component of hemostasis and would, in fact, promote rather than
prevent bleeding.
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### Ques on 2
Which of the following medica ons would decrease a person’s risk for clo ng?
Select all that apply.
- Heparin
- Warfarin
- Lovenox (enoxaparin)
Verified Explana on:
Heparin, warfarin, and Lovenox are an coagulants that interfere with different
aspects of coagula on. Heparin and Lovenox (a low-molecular-weight heparin)
enhance an thrombin III ac vity, while warfarin inhibits vitamin K-dependent
, synthesis of clo*ng factors. Vitamin K is needed for clo*ng factor synthesis and
could promote clo*ng if used in excess.
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A deficiency in which of the following would lead to a hypercoagulable state?
Select all that apply.
- Protein C
- Protein S
- An thrombin III
Verified Explana on:
Protein C, Protein S, and An thrombin III are endogenous an coagulants.
Deficiencies in these increase the risk for hypercoagulable states. Factors II, VII, IX,
X, and prothrombin deficiencies lead to bleeding disorders, not clo*ng.
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### Ques on 3
Which of the following is NOT a hypercoagulable state? Select all that apply.
- Hemophilia A
- Hemophilia B
- Thrombocytopenia