Microbiology Chapter 13 Test Questions
with Verified Answers
We sometimes are able to generate antibodies (immune system proteins) that bind to and
cover up some of the proteins on the outermost portion of a virus while it is in the
bloodstream. This renders the virus unable to reproduce. Which step of viral replication are
antibodies directly preventing?
synthesis
uncoating
assembly
attachment - Ans -attachment
Enveloped viruses have a layer of lipids surrounding their capsid. This envelope is made
mostly of host cell membrane. In which step does the virus acquire this envelope?
release
attachment
synthesis
assembly - Ans -release
What occurs during viral uncoating?
The nucleic acid breaks apart, allowing for translation.
The capsid breaks apart, releasing the viral genome.
The viral envelope is released.
The viral proteins are synthesized. - Ans -The capsid breaks apart, releasing the viral
genome.
The normal function of the PrP protein in mammals is believed to be:
1
Page
assisting in normal membrane development and function.
, assisting proteins in forming beta-pleated sheets.
assisting in normal synaptic development and function.
assisting proteins in forming alpha-helices. - Ans -assisting in normal synaptic
development and function.
How do normal prion proteins (PrP) differ from the infectious prion proteins?
Normal PrP are found in all mammals; infectious PrP are found in only cows.
Normal PrP lack nucleic acid; infectious PrP have nucleic acid.
Normal PrP have alpha-helices; infectious PrP have beta-pleated sheets.
Normal PrP are found on mammals; infectious PrP are found on reptiles. - Ans -
Normal PrP have alpha-helices; infectious PrP have beta-pleated sheets.
How does the number of infectious prions increase?
Prions transform normal proteins into the misfolded beta-pleated sheet configuration;
therefore, prions multiply by conversion.
Prions form multimers which can then form more single copies of the prion protein.
Prions reproduce by binary fission.
Prions reproduce by mitosis. - Ans -Prions transform normal proteins into the
misfolded beta-pleated sheet configuration; therefore, prions multiply by conversion.
Why are the beta-pleated multimers of PrP potentially pathogenic?
They are found on the surface of immune cells, resulting in damage to the immune system.
They are not detected by other organisms.
The multimers are more stable and resistant to protease.
They repress the immune system. - Ans -The multimers are more stable and resistant
to protease.
2
Page
with Verified Answers
We sometimes are able to generate antibodies (immune system proteins) that bind to and
cover up some of the proteins on the outermost portion of a virus while it is in the
bloodstream. This renders the virus unable to reproduce. Which step of viral replication are
antibodies directly preventing?
synthesis
uncoating
assembly
attachment - Ans -attachment
Enveloped viruses have a layer of lipids surrounding their capsid. This envelope is made
mostly of host cell membrane. In which step does the virus acquire this envelope?
release
attachment
synthesis
assembly - Ans -release
What occurs during viral uncoating?
The nucleic acid breaks apart, allowing for translation.
The capsid breaks apart, releasing the viral genome.
The viral envelope is released.
The viral proteins are synthesized. - Ans -The capsid breaks apart, releasing the viral
genome.
The normal function of the PrP protein in mammals is believed to be:
1
Page
assisting in normal membrane development and function.
, assisting proteins in forming beta-pleated sheets.
assisting in normal synaptic development and function.
assisting proteins in forming alpha-helices. - Ans -assisting in normal synaptic
development and function.
How do normal prion proteins (PrP) differ from the infectious prion proteins?
Normal PrP are found in all mammals; infectious PrP are found in only cows.
Normal PrP lack nucleic acid; infectious PrP have nucleic acid.
Normal PrP have alpha-helices; infectious PrP have beta-pleated sheets.
Normal PrP are found on mammals; infectious PrP are found on reptiles. - Ans -
Normal PrP have alpha-helices; infectious PrP have beta-pleated sheets.
How does the number of infectious prions increase?
Prions transform normal proteins into the misfolded beta-pleated sheet configuration;
therefore, prions multiply by conversion.
Prions form multimers which can then form more single copies of the prion protein.
Prions reproduce by binary fission.
Prions reproduce by mitosis. - Ans -Prions transform normal proteins into the
misfolded beta-pleated sheet configuration; therefore, prions multiply by conversion.
Why are the beta-pleated multimers of PrP potentially pathogenic?
They are found on the surface of immune cells, resulting in damage to the immune system.
They are not detected by other organisms.
The multimers are more stable and resistant to protease.
They repress the immune system. - Ans -The multimers are more stable and resistant
to protease.
2
Page
