1 Exampromax - Stuvia US 2025/2026
Biochemistry Final Exam: UNE CHEM 1005
Questions and Answers (100% Correct
Answers) Already Graded A+
Quiz: Control of Fatty Acid Synthesis vs. Oxidation - ⼀Answer: When
Insulin is HIGH --> fatty acid synthesis occurs
When Glucagon is HIGH --> lipolysis, fatty acid B-oxidation, ketogenesis
occur
© 2025 Assignment Expert
Exampromax - Stuvia US
**These never happen at the same time!
Quiz: Lipolysis - ⼀Answer: Process of releasing free fatty acids from
triacylglycerols stored in the adipose IN THE FASTED STATE
Quiz: Steps of lipolysis - ⼀Answer: 1) Hormone Sensitive Lipase:
activated by glucagon and epinephrine
TAGs are hydrolyzed into FFAs and glycerol (inhibited by insulin)
2) Long chain FFAs travel bound to albumin to peripheral tissues to be used
as energy source
3) Glycerol travels to liver to be used as gluconeogenesis substrate
4) Acyl-CoA Synthetase: can reconvert FFAs to acyl-CoA to be used for re-
esterification in the adipose (continuous cycle of lipolysis & re-esterification)
Quiz: Beta Oxidation - ⼀Answer: Process of generating acetyl-CoA,
NADH, and FADH2 from the oxidation of FFAs taken up by peripheral
tissues (mostly liver & skel. muscle tissue).
, 2 Exampromax - Stuvia US 2025/2026
Happens in mitochondria. Long chain FFAs cannot cross the mito
membrane, so a transport system is in place.
Quiz: Ketogenesis - ⼀Answer: Process of generating ketones from
excess acteyl-CoA produced from Beta-Oxidation
Mitochondrial pathway
Quiz: Ketones can be used as fuel by other tissues but cannot be oxidized
by... - ⼀Answer: The liver.
© 2025 Assignment Expert
Exampromax - Stuvia US
Skeletal muscle can oxidize ketones.
The brain will oxidize ketones when starving.
Quiz: Ketogenesis is regulated by... - ⼀Answer: 1) Activity of lipolysis
2) Cytosolic levels of malonyl-CoA (which inhibit CPTI)
3) Flux through the TCA depending on NADH levels & concentration of
intermediates (especially OAA)
Quiz: Ketoacidosis can occur from prolonged ketogenesis, such as... - ⼀
Answer: During starvation and uncontrolled diabetes
Quiz: Important connections between Beta-Oxidation and other
pathways - ⼀Answer: 1) It supplies high levels of ATP in the fasted state
2) ATP is required for both process of glucose synthesis via gluconeogenesis
& nitrogen disposal via the urea cycle
3) deficiencies in beta-oxidation can result in hypoglycemia due to inability
to support glucose synthesis (such as CPTI deficiency, or medium chain
acyl-dehydrogenase deficiency)
, 3 Exampromax - Stuvia US 2025/2026
Quiz: Fatty Acid Synthesis: Activators & Inhibitors - ⼀Answer:
Activated by insulin
Inhibited by glucagon
Quiz: Fatty acid synthesis takes place in the... - ⼀Answer: Cytosol
Quiz: Fatty acid synthesis: what occurs in the mitochondria? - ⼀Answer:
Substrates need to be shuttled out of the mitochondria
© 2025 Assignment Expert
Exampromax - Stuvia US
In the mito:
-Acetyl-CoA and OAA in the mito --> citrate
-Tricarboxylate transporter --> removes excess citrate from the mito
Quiz: Fatty acid elongation - ⼀Answer: Requires malonyl-CoA, fatty
acyl-CoA and NADPH.
This pathway determines the chain length for fatty acids (medium, long,
etc.)
Quiz: Fatty acid synthesis connection to the PPP - ⼀Answer: PPP
provides glycerol (for TAG synthesis) and NADPH (for fatty acid synthesis)
Quiz: Fate of newly synthesized fatty acids - ⼀Answer: -Fatty acids are
NOT stored in the liver
-instead, they're packaged into VLDL particles as TAGs (along with
cholesterol) and are transported to adipose for storage
Biochemistry Final Exam: UNE CHEM 1005
Questions and Answers (100% Correct
Answers) Already Graded A+
Quiz: Control of Fatty Acid Synthesis vs. Oxidation - ⼀Answer: When
Insulin is HIGH --> fatty acid synthesis occurs
When Glucagon is HIGH --> lipolysis, fatty acid B-oxidation, ketogenesis
occur
© 2025 Assignment Expert
Exampromax - Stuvia US
**These never happen at the same time!
Quiz: Lipolysis - ⼀Answer: Process of releasing free fatty acids from
triacylglycerols stored in the adipose IN THE FASTED STATE
Quiz: Steps of lipolysis - ⼀Answer: 1) Hormone Sensitive Lipase:
activated by glucagon and epinephrine
TAGs are hydrolyzed into FFAs and glycerol (inhibited by insulin)
2) Long chain FFAs travel bound to albumin to peripheral tissues to be used
as energy source
3) Glycerol travels to liver to be used as gluconeogenesis substrate
4) Acyl-CoA Synthetase: can reconvert FFAs to acyl-CoA to be used for re-
esterification in the adipose (continuous cycle of lipolysis & re-esterification)
Quiz: Beta Oxidation - ⼀Answer: Process of generating acetyl-CoA,
NADH, and FADH2 from the oxidation of FFAs taken up by peripheral
tissues (mostly liver & skel. muscle tissue).
, 2 Exampromax - Stuvia US 2025/2026
Happens in mitochondria. Long chain FFAs cannot cross the mito
membrane, so a transport system is in place.
Quiz: Ketogenesis - ⼀Answer: Process of generating ketones from
excess acteyl-CoA produced from Beta-Oxidation
Mitochondrial pathway
Quiz: Ketones can be used as fuel by other tissues but cannot be oxidized
by... - ⼀Answer: The liver.
© 2025 Assignment Expert
Exampromax - Stuvia US
Skeletal muscle can oxidize ketones.
The brain will oxidize ketones when starving.
Quiz: Ketogenesis is regulated by... - ⼀Answer: 1) Activity of lipolysis
2) Cytosolic levels of malonyl-CoA (which inhibit CPTI)
3) Flux through the TCA depending on NADH levels & concentration of
intermediates (especially OAA)
Quiz: Ketoacidosis can occur from prolonged ketogenesis, such as... - ⼀
Answer: During starvation and uncontrolled diabetes
Quiz: Important connections between Beta-Oxidation and other
pathways - ⼀Answer: 1) It supplies high levels of ATP in the fasted state
2) ATP is required for both process of glucose synthesis via gluconeogenesis
& nitrogen disposal via the urea cycle
3) deficiencies in beta-oxidation can result in hypoglycemia due to inability
to support glucose synthesis (such as CPTI deficiency, or medium chain
acyl-dehydrogenase deficiency)
, 3 Exampromax - Stuvia US 2025/2026
Quiz: Fatty Acid Synthesis: Activators & Inhibitors - ⼀Answer:
Activated by insulin
Inhibited by glucagon
Quiz: Fatty acid synthesis takes place in the... - ⼀Answer: Cytosol
Quiz: Fatty acid synthesis: what occurs in the mitochondria? - ⼀Answer:
Substrates need to be shuttled out of the mitochondria
© 2025 Assignment Expert
Exampromax - Stuvia US
In the mito:
-Acetyl-CoA and OAA in the mito --> citrate
-Tricarboxylate transporter --> removes excess citrate from the mito
Quiz: Fatty acid elongation - ⼀Answer: Requires malonyl-CoA, fatty
acyl-CoA and NADPH.
This pathway determines the chain length for fatty acids (medium, long,
etc.)
Quiz: Fatty acid synthesis connection to the PPP - ⼀Answer: PPP
provides glycerol (for TAG synthesis) and NADPH (for fatty acid synthesis)
Quiz: Fate of newly synthesized fatty acids - ⼀Answer: -Fatty acids are
NOT stored in the liver
-instead, they're packaged into VLDL particles as TAGs (along with
cholesterol) and are transported to adipose for storage
