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First Aid USMLE STEP 1: Microbiology / Exam Q-Bank / Comprehensive Newest Updated Actual Questions & Answers (A+ Guide Solution)

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First Aid USMLE STEP 1: Microbiology / Exam Q-Bank / Comprehensive Newest Updated Actual Questions & Answers (A+ Guide Solution) Terms in this set (571) Quiz____? Cell Wall Overall Picture - Compare *Gram (+) to Gram (-)* - Answer Quiz____? *Flagellum* on bacteria is composed of what? What is the function? - Answer Composition: Proteins Function: motility Quiz____? *Pilus/Fimbria* on bacteria is composed of what? What is the function? - Answer Composition: Glycoprotein Function: Mediate adherence of bacteria to cell surface, sex plus during conjugation.

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First Aid USMLE STEP 1: Microbiology
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First Aid USMLE STEP 1: Microbiology

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Terms in this set (571)

Quiz____?

Cell Wall Overall Picture - Compare *Gram (+) to Gram (-)* -

Answer✓✓




Quiz____?

*Flagellum* on bacteria is composed of what? What is the function? -

Answer✓✓

Composition: Proteins

Function: motility




Quiz____?

*Pilus/Fimbria* on bacteria is composed of what? What is the function? -

Answer✓✓

Composition: Glycoprotein



1

, Function: Mediate adherence of bacteria to cell surface, sex plus during conjugation.




Quiz____?

*Spore* formation is ONLY possible is what type of bacteria? Why is the formation of spores

important/beneficial?

What is the composition of a spore? -

Answer✓✓

Gram Positive Only

Function: Resistant to dehydration, heat, and chemicals.



Composition: Keratin-like coat; dipicolinic acid; peptidoglycan.




Quiz____?

*Capsule* will be composed of what on bacteria? What is the benefit of a capsule? -

Answer✓✓

Function: Protects against phagocytosis



Composition: Organized, discrete polysaccharide layer (except Bacillus anthracis, which

contains d-glutamate)




2

, Quiz____?

Glycocalyx -

Answer✓✓

Function: Mediates adherance to surfaces, especially foreign surfaces (e.g., indwelling catheters)



Composition:Loose network of polysaccharides




Quiz____?

Periplasm -

Answer✓✓

Space between the cytoplasmic membrane and outer membrane in gram-negative bacteria

(peptidoglycan in the middle)



Gram Neg only

Accumulates components exiting gram neg cells, including hydrolytic enzymes (β-lactamases)




Quiz____?

Outer membrane (gram negatives) -

Answer✓✓

Gram Neg Only

Function:


3

, 1. Endotoxin: Lipid A induces TNF and IL-1; O polysaccharide is antigenic

2. Most OMPs are antigenic

Porins: transport across outer membrane



Composition:

1. Outer Leaflet: endotoxin lipopolysaccharide [LPS/LOS]

2. Embedded proteins: porins and other outer membrane proteins (OMPs)

3. Inner Leaflet: phospholipids




Quiz____?

Cell wall and Gram Stain -

Answer✓✓

Composition: Peptidoglycan is a sugar backbone with peptide chains cross-linked by

transpeptidase



Function: Net-like structure give rigid support, protects against osmotic pressure damage.



Gram Stain:

Thick peptidoglycan layer retains crystal violet = gram +



Thin peptidoglycan layer turns red or pink with counterstain = gram -




4

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First Aid USMLE STEP 1: Microbiology

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