NURS 5220/ NURS5220 EXAM 3 |
COMPLETE 2025 ACTUAL EXAM WITH
CORRECT VERIFIED ANSWERS |
GUARANTEED A+ EXAM EXCELLENCE
What is ACHE? - ✔✔✔ Correct Answer > Acetylcholine esterase is an
enzyme that metabolizes ACh.
What are the active metabolites of benzodiazepines? - ✔✔✔
Correct Answer > Diazepam (with a half-life exceeding 100 hours)
and midazolam (rapidly metabolized to an α-hydroxylated
compound with biologic activity).
What effect do high doses of benzodiazepines have on CMR02 & CBF?
-
✔✔✔ Correct Answer > They reduce CMR02 & CBF.
,What are the adverse effects of midazolam? - ✔✔✔ Correct
Answer > Prolonged sedation, impaired cognition and
psychomotor performance, unwanted amnesia, potential for
delirium, increased risk of accidents and falls, dependence and
withdrawal effects
What effect do benzodiazepines have on the threshold to local
anesthetic-induced seizures? - ✔✔✔ Correct Answer > They
increase the threshold to local anesthetic-induced seizures.
Which benzodiazepines have no active metabolites? - ✔✔✔ Correct
Answer > Oxazepam, lorazepam, and temazepam.
What factors can alter the metabolism of benzodiazepines? - ✔✔✔
Correct Answer > Disease and age.
,What is the duration of action of benzodiazepines primarily
determined by? - ✔✔✔ Correct Answer > The α phase (distribution-
redistribution from CNS) dynamics rather than the rate of
elimination.
What are the pharmacodynamic effects of benzodiazepines on the
CNS? - ✔✔✔ Correct Answer > CNS depressant effects including
anxiolysis, sedation, sleep, anticonvulsant, amnesia, muscle
relaxation, and inhibition of alcohol withdrawal symptoms.
What is the dose-related effect of benzodiazepines on anterograde
amnesia? - ✔✔✔ Correct Answer > They cause anterograde
amnesia at high doses.
What are the potential drawbacks of benzodiazepine use? - ✔✔✔
Correct Answer > Awareness regarding addiction, withdrawal,
, recreational abuse, and the development of other drug classes has
led to a decline in their use.
Which CYP enzyme is primarily responsible for the metabolism of
benzodiazepines? - ✔✔✔ Correct Answer > CYP3A4.
Which benzodiazepine has a half-life exceeding 100 hours? - ✔✔✔
Correct Answer > Diazepam.
Which benzodiazepine is rapidly metabolized to an α-hydroxylated
compound with biologic activity? - ✔✔✔ Correct Answer >
Midazolam.
Which benzodiazepines have no active metabolites? - ✔✔✔ Correct
Answer > Oxazepam, lorazepam, and temazepam.
COMPLETE 2025 ACTUAL EXAM WITH
CORRECT VERIFIED ANSWERS |
GUARANTEED A+ EXAM EXCELLENCE
What is ACHE? - ✔✔✔ Correct Answer > Acetylcholine esterase is an
enzyme that metabolizes ACh.
What are the active metabolites of benzodiazepines? - ✔✔✔
Correct Answer > Diazepam (with a half-life exceeding 100 hours)
and midazolam (rapidly metabolized to an α-hydroxylated
compound with biologic activity).
What effect do high doses of benzodiazepines have on CMR02 & CBF?
-
✔✔✔ Correct Answer > They reduce CMR02 & CBF.
,What are the adverse effects of midazolam? - ✔✔✔ Correct
Answer > Prolonged sedation, impaired cognition and
psychomotor performance, unwanted amnesia, potential for
delirium, increased risk of accidents and falls, dependence and
withdrawal effects
What effect do benzodiazepines have on the threshold to local
anesthetic-induced seizures? - ✔✔✔ Correct Answer > They
increase the threshold to local anesthetic-induced seizures.
Which benzodiazepines have no active metabolites? - ✔✔✔ Correct
Answer > Oxazepam, lorazepam, and temazepam.
What factors can alter the metabolism of benzodiazepines? - ✔✔✔
Correct Answer > Disease and age.
,What is the duration of action of benzodiazepines primarily
determined by? - ✔✔✔ Correct Answer > The α phase (distribution-
redistribution from CNS) dynamics rather than the rate of
elimination.
What are the pharmacodynamic effects of benzodiazepines on the
CNS? - ✔✔✔ Correct Answer > CNS depressant effects including
anxiolysis, sedation, sleep, anticonvulsant, amnesia, muscle
relaxation, and inhibition of alcohol withdrawal symptoms.
What is the dose-related effect of benzodiazepines on anterograde
amnesia? - ✔✔✔ Correct Answer > They cause anterograde
amnesia at high doses.
What are the potential drawbacks of benzodiazepine use? - ✔✔✔
Correct Answer > Awareness regarding addiction, withdrawal,
, recreational abuse, and the development of other drug classes has
led to a decline in their use.
Which CYP enzyme is primarily responsible for the metabolism of
benzodiazepines? - ✔✔✔ Correct Answer > CYP3A4.
Which benzodiazepine has a half-life exceeding 100 hours? - ✔✔✔
Correct Answer > Diazepam.
Which benzodiazepine is rapidly metabolized to an α-hydroxylated
compound with biologic activity? - ✔✔✔ Correct Answer >
Midazolam.
Which benzodiazepines have no active metabolites? - ✔✔✔ Correct
Answer > Oxazepam, lorazepam, and temazepam.
