Basic Immunology
,INTRODUCTION
◼ Immunology is the study of host
defence mechanisms.
◼ Immunity is the ability of the host to
protect itself against foreign organisms.
◼ The immune system comprises the
tissues, cells & molecules which mount
the immune response.
, Complement
Coagulation Cascade
Cascade Thrombin
Plasma Fibrinogen Fibrin
XIIa
Fibrinolytic Plasmin
Cascade
Bradykinin
Kinin Kallikrein MAC
PCV Cascade
Cellular mediators
, Immunology
◼ Natural (‘innate’) immune system
– Skin, tears, saliva, mucus, acids
– Property of all living creatures
◼ Adaptive (‘acquired’) immune system
– Specialist cells, cytokines, antibodies
– Specific and has ‘memory’
– Specialised mucosal lymphoid tissue
,INTRODUCTION
◼ Immunology is the study of host
defence mechanisms.
◼ Immunity is the ability of the host to
protect itself against foreign organisms.
◼ The immune system comprises the
tissues, cells & molecules which mount
the immune response.
, Complement
Coagulation Cascade
Cascade Thrombin
Plasma Fibrinogen Fibrin
XIIa
Fibrinolytic Plasmin
Cascade
Bradykinin
Kinin Kallikrein MAC
PCV Cascade
Cellular mediators
, Immunology
◼ Natural (‘innate’) immune system
– Skin, tears, saliva, mucus, acids
– Property of all living creatures
◼ Adaptive (‘acquired’) immune system
– Specialist cells, cytokines, antibodies
– Specific and has ‘memory’
– Specialised mucosal lymphoid tissue
