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Basic Immunology

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1-Which of the following molecules presents on all T cells? a. CD1 b. CD3 c. CD20 d. CD2 2-Which of the following molecules is expressed on the surface of B cells? a. CD4 b. CD3 c. CD19 d. CD28 3-Which of the following cells forming the largest % in WBC differential count in adult? a. Lymphocyte b. Mast cell c. Macrophage d. Neutrophil 4- Which of the following cells in antigen presenting cell? a. Basophil b. Mast cell c. Macrophage d. Neutrophil 5- Which of the following organs consider primary lymphoid organ? a. Lymph nodes b. Spleen c. Tonsils d. Thymus 6- As regard T cell maturation, which of the following organs consider primary lymphoid organ? a. Bone marrow b. Spleen c. Tonsils d. Thymus 7- Which of the following cells consider phagocytic cell? a. Basophil b. Mast cell c. Neutrophil

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1. Which of the following molecules presents on all T cells?
a. CD1
b. CD3
c. CD20
d. CD16

2. Which of the following molecules is expressed on the surface of B cells?
a. CD4
b. CD3
c. CD19
d. CD28

3. Which of the following cells is professional antigen presenting cell?
a. Basophil
b. Mast cell
c. Macrophage
d. Neutrophil.

4. Which of the following organs consider primary lymphoid organ?
a. Lymph nodes
b. Spleen
c. Tonsils
d. Thymus

5. Which of the following cells forming the largest % in WBC differential count
in adult?
a. Basophil
b. Mast cell
c. Macrophage
d. Neutrophil

6. As regard chemical nature of antigen, what is the most potent antigen?
a. Lipids
b. Nucleic acids
c. Proteins
d. Polysaccharides

7. Which of the following chemical component consider T- independent
antigens?
a. Lipids
b. Nucleic acids
c. Proteins
d. Polysaccharides

, 8. As regard T- dependent antigens, what is\are the Stimulated cell (s)
and antibody class (es) produced?
a. Both T & B cells- IgM only
b. Both T & B cells- All antibody classes
c. B cells only - All antibody classes
d. B cells only - IgM only

9. As regard Superantigens, it is …….antigen and activate T cell with
production ……….
a. Processed - monoclonal activation
b. Processed - polyclonal activation
c. Not processed - polyclonal activation
d. Not processed - monoclonal activation

10. Which of the following cells have the ability of killing by production of
granzymes?
a. Neutrophils
b. Macrophages
c. Natural killer
d. Mast cells

11. What is the first step in phagocytosis?
a. Engulfment
b. Killing
c. Attachment
d. Chemotaxis

12. In Chronic granulomatous disease (CGD), there is defect in NADPH oxidase
inside macrophage lead to defect in which of the following functions?
a. Killing mechanism
b. Opsonization
c. Antigen presentation
d. Cytokine production

13. Which one of the following cells is responsible about production of Pro-
inflammatory cytokines: IL-1, IL-6 and TNF-α?
a. Neutrophils
b. Macrophages
c. Natural killer
d. Mast cells


14. One of the most Therapeutic Use of Interferons (IFNs) is elimination of
which one of the following pathogens?

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