NR565 / NR565 ADVANCED PHARMACOLOGY FUNDAMENTALS
MIDTERM / FINAL EXAM| QUESTIONS AND 100 % CORRECT ANSWERS
| RATED A QUIZ BANK | LATEST, | CHAMBERLAIN
COLLEGE
Used in children aged 9-11 and 19-21, and adults every 5 years after 20, with greater
risk for those with diabetes and a risk score >7.5% - (answer)ASCVD Risk Score
Can be used in pregnancy/breastfeeding, as monotherapy or adjunct therapy with a
statin or fibrate - (answer)Ezetimibe Use
Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreasing absorption
from the small intestine, without affecting triglycerides - (answer)Ezetimibe
Non-drug measures to lower LDL, including diet, exercise, weight control, and smoking
cessation - (answer)Lifestyle Changes for High Cholesterol
Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for generally well-
tolerated side effects - (answer)Minimizing Side Effects
Direct relaxant effect on vascular smooth muscles, dilation of coronary vessels,
reduction of preload and afterload, and promotion of vasodilation - (answer)Organic
Nitrates Therapeutic Action
Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes, including
grapefruit juice, HIV protease inhibitors, macrolide antibiotics, azole antifungal drugs,
and some CCB - (answer)Ranolazine Contraindications
Avoid in children under 10 - (answer)Statin Prescription Age
Promotes relaxation of coronary artery spasm, increasing cardiac oxygen supply -
(answer)CCB Role in Variant Angina
Aldosterone antagonist that promotes myocardial remodeling and fibrosis to help with
symptoms - (answer)HF Worsening Symptoms Medication
Promotes relaxation of peripheral arterioles, decreasing afterload and reducing cardiac
oxygen demand - (answer)CCB Stable Angina
Prescribe a BB to help with increased heart rate - (answer)Nitro Patches Side Effect
Response
When not used correctly, they lead to increased side effects, adverse reactions, and
toxicity - (answer)CYP450 Inhibitors and Reducers
, In patients with infrequent flareups (less than three per year), NSAIDs are the first line
agent for relieving pain - (answer)Gouty Arthritis Treatment Decision
Prescribe a glucocorticoid (prednisone) or make dietary changes - (answer)Gouty
Arthritis NSAID Ineffectiveness
Considered for long term treatment if a person has three or more gouty attacks per year
- (answer)Colchicine Long Term Treatment
Should not be taken with statins or CYP3A4 inhibitors - (answer)Colchicine
Contraindications
Nausea, vomiting, diarrhea, myelosuppression, myopathy, and rhabdomyolysis -
(answer)Colchicine Adverse Effects
Can lead to severe cutaneous adverse reaction (SCAR) with symptoms like rash, fever,
eosinophilia, and liver and kidney function issues - (answer)Allopurinol Long Term
Effect
Should be co-administered with NSAIDs or colchicine - (answer)Febuxostat Co-
Administration
Erosion and irreversible joint damage, renal damage, and tophi formation -
(answer)Untreated Gout Complications
Minimize risk of esophagitis by swallowing the pill whole with a full glass of water, then
sitting up for at least 30 min, and taking the med 30 min prior to other intake -
(answer)Alendronate Patient Education
Interferes with calcium, magnesium, and iron absorption - (answer)Ibandronate Dietary
Supplement Interference
Alendronate is the first line treatment - (answer)Osteoporosis 1st Line Treatment
Safe to use in patients with renal dysfunction or who over produce uric acid -
(answer)Allopurinol Safety in Renal Dysfunction
Includes CBC with WBC differential, s/s of infection, malignancies, pregnancy rule out,
ALT, AST, serum creatinine, comprehensive history and physical exam, and
assessment of immunocompetence and liver and renal status - (answer)DMARDs
Baseline Diagnostics
Includes chest x-ray with emphasis on pulmonary and GI status - (answer)Methotrexate
Baseline Data
Hydroxychloroquine - (answer)DMARD Requiring Ophthalmologic and Cardiac Exam
MIDTERM / FINAL EXAM| QUESTIONS AND 100 % CORRECT ANSWERS
| RATED A QUIZ BANK | LATEST, | CHAMBERLAIN
COLLEGE
Used in children aged 9-11 and 19-21, and adults every 5 years after 20, with greater
risk for those with diabetes and a risk score >7.5% - (answer)ASCVD Risk Score
Can be used in pregnancy/breastfeeding, as monotherapy or adjunct therapy with a
statin or fibrate - (answer)Ezetimibe Use
Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreasing absorption
from the small intestine, without affecting triglycerides - (answer)Ezetimibe
Non-drug measures to lower LDL, including diet, exercise, weight control, and smoking
cessation - (answer)Lifestyle Changes for High Cholesterol
Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for generally well-
tolerated side effects - (answer)Minimizing Side Effects
Direct relaxant effect on vascular smooth muscles, dilation of coronary vessels,
reduction of preload and afterload, and promotion of vasodilation - (answer)Organic
Nitrates Therapeutic Action
Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes, including
grapefruit juice, HIV protease inhibitors, macrolide antibiotics, azole antifungal drugs,
and some CCB - (answer)Ranolazine Contraindications
Avoid in children under 10 - (answer)Statin Prescription Age
Promotes relaxation of coronary artery spasm, increasing cardiac oxygen supply -
(answer)CCB Role in Variant Angina
Aldosterone antagonist that promotes myocardial remodeling and fibrosis to help with
symptoms - (answer)HF Worsening Symptoms Medication
Promotes relaxation of peripheral arterioles, decreasing afterload and reducing cardiac
oxygen demand - (answer)CCB Stable Angina
Prescribe a BB to help with increased heart rate - (answer)Nitro Patches Side Effect
Response
When not used correctly, they lead to increased side effects, adverse reactions, and
toxicity - (answer)CYP450 Inhibitors and Reducers
, In patients with infrequent flareups (less than three per year), NSAIDs are the first line
agent for relieving pain - (answer)Gouty Arthritis Treatment Decision
Prescribe a glucocorticoid (prednisone) or make dietary changes - (answer)Gouty
Arthritis NSAID Ineffectiveness
Considered for long term treatment if a person has three or more gouty attacks per year
- (answer)Colchicine Long Term Treatment
Should not be taken with statins or CYP3A4 inhibitors - (answer)Colchicine
Contraindications
Nausea, vomiting, diarrhea, myelosuppression, myopathy, and rhabdomyolysis -
(answer)Colchicine Adverse Effects
Can lead to severe cutaneous adverse reaction (SCAR) with symptoms like rash, fever,
eosinophilia, and liver and kidney function issues - (answer)Allopurinol Long Term
Effect
Should be co-administered with NSAIDs or colchicine - (answer)Febuxostat Co-
Administration
Erosion and irreversible joint damage, renal damage, and tophi formation -
(answer)Untreated Gout Complications
Minimize risk of esophagitis by swallowing the pill whole with a full glass of water, then
sitting up for at least 30 min, and taking the med 30 min prior to other intake -
(answer)Alendronate Patient Education
Interferes with calcium, magnesium, and iron absorption - (answer)Ibandronate Dietary
Supplement Interference
Alendronate is the first line treatment - (answer)Osteoporosis 1st Line Treatment
Safe to use in patients with renal dysfunction or who over produce uric acid -
(answer)Allopurinol Safety in Renal Dysfunction
Includes CBC with WBC differential, s/s of infection, malignancies, pregnancy rule out,
ALT, AST, serum creatinine, comprehensive history and physical exam, and
assessment of immunocompetence and liver and renal status - (answer)DMARDs
Baseline Diagnostics
Includes chest x-ray with emphasis on pulmonary and GI status - (answer)Methotrexate
Baseline Data
Hydroxychloroquine - (answer)DMARD Requiring Ophthalmologic and Cardiac Exam
