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What is a reliable indicator of rate erythropoiesis? - ANSWER RPI- reticulocyte
production index
Bronze elliptocyte - ANSWER Most typical finding in sickle cell anemia
Red cell shape- In vivo-neonatal liver disease, McLeod pheno-type (Kx) - ANSWER
Crenated cell
Red cell shape- microangiopathic hemolytic anemia (DIC, TTP,HUS) - ANSWER
Schistocytes
Macroovalocyte - ANSWER Deficiency of B12 folate
Acanthocyte (spur cell) - ANSWER Alcoholic cirrhosis
What red cell shape is indicative of Rh null syndrome? - ANSWER Stomatocyte
Lepocyte (target cell) - ANSWER Hb-C, Hb-E disease, thalassemias, liver disease,
postsplenectomy
Cabot ring - ANSWER DNA remnant
Heinz bodies - ANSWER Ppt Hb or G6PD deficiency
DNA (aberrant chromosomes)-presence usually signifies a damaged spleen -
ANSWER Howell-Jolly Bodies
Flat blue-gray pieces-nonheme Fe - ANSWER Pappenheimer bodies
Sideroblastic anemia - ANSWER Disease in which the bone marrow produces ringed
sideroblasts; the body has iron available but cannot incorporate it into hemoglobin;
granules of iron accumulated in perinuclear mitochondria
Most easily confused with IDA on peripheral smear but not an iron deficiency -
ANSWER Thalassemia minor
High serum iron, normal TIBC, low Hb,Common in Mediterranean area - ANSWER
Beta thalassemia