1 | P a g e | © copyright 2024/2025 | Grade A+
UST ABSN Pathopharmacology 1
Questions & 100% Correct Answers
How do you define the word drug?
✓ ~~> A drug is any chemical that can affect living processes
Define pharmacology
✓ ~~> Pharmacology can be defined as the study of drugs and their
interaction with living things
Define clinical pharmacology
✓ ~~> study of effect of drugs in man (as compared to animals or
comparative pharmacology
what are pharmacotherapeutics?
✓ ~~> also known as therapeutics, pharmacotherapeutics emphasizes
the disease state and its characteristics including therapy for and use
of drugs in prevention and treatment of condition
what are chemotherapeutic agents?
Master01 | September, 2024/2025 | Latest update
, 2 | P a g e | © copyright 2024/2025 | Grade A+
✓ ~~> Drugs used to destroy or eliminate pathogenic cells or organisms.
The term is usually restricted to anti-infectives and cancer
chemotherapy.
what is toxicology and how do we measure a drugs toxicity?
✓ ~~> Toxicology deals with the effects of drugs. Toxicity is measured
through the Therapeutic Index.
What is the therapeutic index?
✓ ~~> therapeutic index is a ratio that measures toxicity. The ratio is
found by putting the dose *capable of killing 50% of animals (LD50)
over than required to acheive a beneficial effect in 50% of animals
(ED50).
In clinical practice the THERAPEUTIC INDEX is described as the ratio of the
dose that causes toxicity over the dose that provides therapeutic effect.
what is tolerance?
✓ ~~> Tolerance is the hyporeactivity that occurring from chronic
exposure to a drug. Achievement of the same effects of the drug
requires larger and larger doses.
Master01 | September, 2024/2025 | Latest update
, 3 | P a g e | © copyright 2024/2025 | Grade A+
What is cross tolerance and how does it occur?
✓ ~~> Cross tolerance may happen when tolerance occurs across
drugs of the same class or across drugs that have the same
pharmacological effects
what are some examples of neurological adaptation/ cellular tolerance to
drugs?
✓ ~~> Tolerance to opioids, barbiturates, and alcohol
What is metabolic drug tolerance?
✓ ~~> metabolic drug tolerance occurs when the body has an
increased rate of elimination of the drug.
what is the most common form of metabolic tolerance?
✓ ~~> enzyme induction which occurs when there is an increased
activity of enzymes (the drug transport system)
What is pharmacodynamics?
✓ ~~> pharmacodynamic processes determine the nature and intensity
of the response. It is essentially the effect of the drug ON the body.
Master01 | September, 2024/2025 | Latest update
UST ABSN Pathopharmacology 1
Questions & 100% Correct Answers
How do you define the word drug?
✓ ~~> A drug is any chemical that can affect living processes
Define pharmacology
✓ ~~> Pharmacology can be defined as the study of drugs and their
interaction with living things
Define clinical pharmacology
✓ ~~> study of effect of drugs in man (as compared to animals or
comparative pharmacology
what are pharmacotherapeutics?
✓ ~~> also known as therapeutics, pharmacotherapeutics emphasizes
the disease state and its characteristics including therapy for and use
of drugs in prevention and treatment of condition
what are chemotherapeutic agents?
Master01 | September, 2024/2025 | Latest update
, 2 | P a g e | © copyright 2024/2025 | Grade A+
✓ ~~> Drugs used to destroy or eliminate pathogenic cells or organisms.
The term is usually restricted to anti-infectives and cancer
chemotherapy.
what is toxicology and how do we measure a drugs toxicity?
✓ ~~> Toxicology deals with the effects of drugs. Toxicity is measured
through the Therapeutic Index.
What is the therapeutic index?
✓ ~~> therapeutic index is a ratio that measures toxicity. The ratio is
found by putting the dose *capable of killing 50% of animals (LD50)
over than required to acheive a beneficial effect in 50% of animals
(ED50).
In clinical practice the THERAPEUTIC INDEX is described as the ratio of the
dose that causes toxicity over the dose that provides therapeutic effect.
what is tolerance?
✓ ~~> Tolerance is the hyporeactivity that occurring from chronic
exposure to a drug. Achievement of the same effects of the drug
requires larger and larger doses.
Master01 | September, 2024/2025 | Latest update
, 3 | P a g e | © copyright 2024/2025 | Grade A+
What is cross tolerance and how does it occur?
✓ ~~> Cross tolerance may happen when tolerance occurs across
drugs of the same class or across drugs that have the same
pharmacological effects
what are some examples of neurological adaptation/ cellular tolerance to
drugs?
✓ ~~> Tolerance to opioids, barbiturates, and alcohol
What is metabolic drug tolerance?
✓ ~~> metabolic drug tolerance occurs when the body has an
increased rate of elimination of the drug.
what is the most common form of metabolic tolerance?
✓ ~~> enzyme induction which occurs when there is an increased
activity of enzymes (the drug transport system)
What is pharmacodynamics?
✓ ~~> pharmacodynamic processes determine the nature and intensity
of the response. It is essentially the effect of the drug ON the body.
Master01 | September, 2024/2025 | Latest update
