Patho FHEA Midterm Exam Version
Patho FHEA Midterm Exam Version Newest 2025 Actual
Exam Complete 100 Questions And Correct Detailed
Answers(Verified Answers)|Already Graded A+
Based upon knowledge of the physiology of iron deficiency anemia, the clinician knows that
when an adult presents with microcytic anemia and no apparent cause of blood loss,
evaluation, and management should include: - ANSWER-Gastrointestinal endoscopic evaluation
Division of red blood cells and subsequent development of an adequate red blood cell count
relies on the presence of----- in the maturation stages - ANSWER-A nucleus
Hemoglobin synthesis occurs during the reticulocyte stage of red blood cell production. It is a
product of the assembly of: - ANSWER-Four protein chains-- two alpha and two beta.
In order to absorb vitamin B12, the patient must be able to produce intrinsic factor from a
healthy : - ANSWER-Gastric parietal cell
Mature red blood cell development is best described by the following progression: - ANSWER-
Bursting form unit, pro-erythroblast, reticulocyte
The predominant form of healthy hemoglobin in a healthy individual is - ANSWER-Hemoglobin
A1
When evaluating causes of common anemias, the clinician recognizes that the majority of iron
heme synthesis comes from: - ANSWER-Recycled red blood cells
which of the following anemias is characterized by a single amino acid substitution? - ANSWER-
Sickle cell anemia
1|Page
, Patho FHEA Midterm Exam Version
while evaluating the potential causes of macrocytic anemia in a patient, the clinician recognizes
that a history of gastrointestinal surgery is suspicious for which type of anemia - ANSWER-
Pernicious anemia
A fibrin clot is formed to arrest bleeding and prevent exsanguination. Control of the size of the
clot is maintained with which of the following mechanisms - ANSWER-Activation of protein C
Adhesion, aggregation, and secretion are all characteristics of: - ANSWER-Platelet functional
activity
Hemostasis and subsequent arrest of bleeding after vessel injury is a two-step process. Intrinsic
and extrinsic pathway activation are mechanisms of clotting that share which common feature?
- ANSWER-Activation of factor x
In the cell-based model of clotting, thrombin activates all of the following except - ANSWER-
plasminogen
The cell- based model of clotting highlights the role of thrombin as---- activation which results in
positive feedback cycle of clot extension. - ANSWER-Platelet
The cell-based model of clotting is a relatively new theory and offers a different approach to the
relationship between primary and secondary clotting. The defining feature of this theory is that
it: - ANSWER-Reflects the interrelated role that thrombin plays in both fibrinogen and platelet
activation
The primary function of plasmin is to: - ANSWER-Degrade the clot.
The three phases of the cell-based model of clotting are: - ANSWER-Initiation, amplification,
propagation.
2|Page
, Patho FHEA Midterm Exam Version
Clotting disorders include all of the following except: - ANSWER-Peripheral arterial disease.
The majority of cases of hemophilia are due to a deficiency of: - ANSWER-Factor VIII.
The type of leukocyte responsible for fighting bacterial infections is: - ANSWER-Neutrophils
The type of leukocyte responsible for responding to allergic events and parasitic infection is: -
ANSWER-Eosinophils
Vitamin K is required for all of the following clotting factors except: - ANSWER-Plasminogen
For a patient with thrombocytopenia, the risk of appreciable bleeding is negligible until the
platelet count reaches: - ANSWER-<50,000/mm³.
Which of the following is consistent with a "left shift" differential? - ANSWER-Neutrophils at
82%
In a healthy individual, the highest proportion of leukocytes will consist of - ANSWER-
Neutrophils
Treatment of a patient with excessive bleeding caused by disseminated intravascular
coagulation can include the use of: - ANSWER-Heparin
Rate-setting slow response cardiac tissue will depolarize independent of autonomic influence.
However, in the presence of sympathetic stimulation, what is the physiologic process that
increases heart rate? - ANSWER-Lower depolarization threshold
3|Page
Patho FHEA Midterm Exam Version Newest 2025 Actual
Exam Complete 100 Questions And Correct Detailed
Answers(Verified Answers)|Already Graded A+
Based upon knowledge of the physiology of iron deficiency anemia, the clinician knows that
when an adult presents with microcytic anemia and no apparent cause of blood loss,
evaluation, and management should include: - ANSWER-Gastrointestinal endoscopic evaluation
Division of red blood cells and subsequent development of an adequate red blood cell count
relies on the presence of----- in the maturation stages - ANSWER-A nucleus
Hemoglobin synthesis occurs during the reticulocyte stage of red blood cell production. It is a
product of the assembly of: - ANSWER-Four protein chains-- two alpha and two beta.
In order to absorb vitamin B12, the patient must be able to produce intrinsic factor from a
healthy : - ANSWER-Gastric parietal cell
Mature red blood cell development is best described by the following progression: - ANSWER-
Bursting form unit, pro-erythroblast, reticulocyte
The predominant form of healthy hemoglobin in a healthy individual is - ANSWER-Hemoglobin
A1
When evaluating causes of common anemias, the clinician recognizes that the majority of iron
heme synthesis comes from: - ANSWER-Recycled red blood cells
which of the following anemias is characterized by a single amino acid substitution? - ANSWER-
Sickle cell anemia
1|Page
, Patho FHEA Midterm Exam Version
while evaluating the potential causes of macrocytic anemia in a patient, the clinician recognizes
that a history of gastrointestinal surgery is suspicious for which type of anemia - ANSWER-
Pernicious anemia
A fibrin clot is formed to arrest bleeding and prevent exsanguination. Control of the size of the
clot is maintained with which of the following mechanisms - ANSWER-Activation of protein C
Adhesion, aggregation, and secretion are all characteristics of: - ANSWER-Platelet functional
activity
Hemostasis and subsequent arrest of bleeding after vessel injury is a two-step process. Intrinsic
and extrinsic pathway activation are mechanisms of clotting that share which common feature?
- ANSWER-Activation of factor x
In the cell-based model of clotting, thrombin activates all of the following except - ANSWER-
plasminogen
The cell- based model of clotting highlights the role of thrombin as---- activation which results in
positive feedback cycle of clot extension. - ANSWER-Platelet
The cell-based model of clotting is a relatively new theory and offers a different approach to the
relationship between primary and secondary clotting. The defining feature of this theory is that
it: - ANSWER-Reflects the interrelated role that thrombin plays in both fibrinogen and platelet
activation
The primary function of plasmin is to: - ANSWER-Degrade the clot.
The three phases of the cell-based model of clotting are: - ANSWER-Initiation, amplification,
propagation.
2|Page
, Patho FHEA Midterm Exam Version
Clotting disorders include all of the following except: - ANSWER-Peripheral arterial disease.
The majority of cases of hemophilia are due to a deficiency of: - ANSWER-Factor VIII.
The type of leukocyte responsible for fighting bacterial infections is: - ANSWER-Neutrophils
The type of leukocyte responsible for responding to allergic events and parasitic infection is: -
ANSWER-Eosinophils
Vitamin K is required for all of the following clotting factors except: - ANSWER-Plasminogen
For a patient with thrombocytopenia, the risk of appreciable bleeding is negligible until the
platelet count reaches: - ANSWER-<50,000/mm³.
Which of the following is consistent with a "left shift" differential? - ANSWER-Neutrophils at
82%
In a healthy individual, the highest proportion of leukocytes will consist of - ANSWER-
Neutrophils
Treatment of a patient with excessive bleeding caused by disseminated intravascular
coagulation can include the use of: - ANSWER-Heparin
Rate-setting slow response cardiac tissue will depolarize independent of autonomic influence.
However, in the presence of sympathetic stimulation, what is the physiologic process that
increases heart rate? - ANSWER-Lower depolarization threshold
3|Page
