MLS 045 LAB UNIT TEST 1
On which organism or sample was the term enzyme literally associated? *
rice
wheat
meat
yeast
Who gave the word “enzymes” to catalytic molecules? *
Pasteur
Kuhne
Buchner
Harden
Which enzymes are used to diagnose liver diseases? *
ACP & ALP
AST & ALT
AMS & LPS
CK & LDH
Kernicterus is an abnormal accumulation of bilirubin in: *
Heart tissue
Brain tissue
Liver tissue
Kidney tissue
A physician suspects his patient has pancreatitis. Which test(s) would be most
indicative of this disease? *
Creatinine
LD isoenzymes
B-hydroxybutyrate
amylase
When myocardial infarction occurs, the first enzyme to become elevated is: *
CK
LD
AST
, MLS 045 -Clinical Chemistry 2 (LABORATORY)
ALT
Which vitamin is required for the normal absorption of dietary calcium: *
Vitamin
Vitamin B12
Vitamin C
Vitamin D
It has bromide as its common interferent in its analysis *
Iodide
Chromium
Zinc
Magnesium
The metal deficient in hypochromic microcytic anemia that forms a complex with TPTZ
(sulfonated bathophenanthroline 2,4,6- tripyridyl-S-triazine) is: *
copper
magnesium
iron
cobalt
A person suspected of having dual case of alkalosis would have which of the following
laboratory findings? *
CO2 content and PCO2 elevated, pH decreased
CO2 content decreased and pH elevated
CO2 content PCO2, and pH decreased
CO2 content and pH elevated
Which of these is NOT a liver function test: *
Thymol turbidity test
TP A/G ratio & BCG test
hemoglobin electrophoresis
Lipid profile
Respiratory acidosis is described as an a (n): *
Increase in CO2 content and PCO2 with a decreased pH
Decrease in CO2 content with an increased pH
Increase in CO2 content with an increased pH
Decrease in CO2 content and PCO2 with decreased pH
What is a coenzyme? *
organic molecules derived from vitamins
organic molecules containing metals
transport molecules
all of these
, MLS 045 -Clinical Chemistry 2 (LABORATORY)
In the bilirubin oxidase method, bilirubin is oxidized to a colorless compound which
is: *
diazotized sulfanilic acid
urobilinogen
biliverdin
bilierythrin
An electrophoretic separation of lactate dehydrogenase isoenzymes that demonstrates
an elevation in LD-1 and LD-2 in a “flipped” pattern is consistent with: *
Myocardial infarction
Viral hepatitis
Pancreatitis
Renal failure
In the determination of lactate dehydrogenase at 340nm, using pyruvate as the
substrate, one actually measures the: *
Decrease in pyruvate
Decrease in NADH
Increase in NADH
Increase in coenzyme
Total lactic dehydrogenase (LD) activity, confirmed to fraction 4 and 5 , is most likely
to be associated with: *
Pulmonary infarction
Hemolytic anemia
Myocardial infarction
Acute viral hepatitis
The aldehyde transport coenzyme is derived from: *
Vitamin A
Vitamin C
Niacin
Thiamine
A critically ill patient becomes comatose. The physician believes the coma is due to
hepatic failure. The assay most helpful in this diagnosis is: *
Ammonia
ALT
AST
GCT
Enzymes that differ in structure and origin but same reaction catalyzed are called: *
Holoenzyme
Apoenzyme
Prosthetic group
, MLS 045 -Clinical Chemistry 2 (LABORATORY)
Isoenzyme
It is one of the best tests for bilirubin: *
Reitman and Frankel
Isaacson – Jensey
Biuret
Jendrassik – Grof
The polarity and water solubility of bile acids are increased upon conjugated with: *
Glycine
Either glycine or taurine
Neither glycine not taurine
Taurine
In early 19the century, which scientist studied fermentation of sugar to alcohol using a
cell-free extract? *
Edward Buchner
Louis Pasteur
Alfred Joseph
Willy Kuhne
Which method uses sulfanilic acid, HCl and sodium nitrite? *
Jaffe
Diazo
Zimmerman
Lowry
Which of the following parameters using ISE does not require a glass membrane
(oxides of Si, Al and Na) ? *
Sodium
Chloride
pH
Calcium
The transport material associated with bilirubin in the liver is? *
alpha 1-globulin
beta-globulin
albumin
ligandin
Which of the following functions as a transport protein for bilirubin in the blood? *
alpha1-globulin
gamma-globulin
beta-globulin
albumin