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What is physiological jaundice? - (answers)-occurs when baby accumulates bilirubin
-secondary to immature liver in newborns
-common first 2-4 days of life and resolves by 2 weeks
What level is conjugated hyperbilirubinemia? - (answers)serum conjugated bilirubin
concentration greater than 1 mg/dL if the total bilirubin is less than 5.0 mg/dL or more than 20%
of the total bilirubin if the the total bilirubin is greater than 5 mg/dL (p. 862 AAP book)
What is breastfeeding jaundice? - (answers)-due to poor intake that causes lack of stools and
urine output
-common in first week and resolves once milk comes in and infant is feeding well-more stools
and urinary output
-peaks around 2-3 weeks
How do you diagnose jaundice? - (answers)-dx with a bili level of 5 mg/dL
,-12 mg/dL threshold for all newborns having jaundiced appearance
-direct/indirect bili levels
-CBC
-reticulocyte count
How do you treat jaundice? - (answers)increased intake
indirect sunlight
phototherapy
IV fluids
What are other causes of jaundice? - (answers)abnormal blood cell shapes (like sickle cell)
Rh incompatibility
cephalohematoma
polycythemia (increased RBCs, SGA infants, twins)
infection
specific enzyme disorders
What is biliary atresia? - (answers)-life-threatening condition causing a blockage of bile ducts
inside or outside of liver
,-leads to build-up of toxins (like bilirubin)
-malabsorption of fat-soluble vitamins A,D,E,K
-scaring of the liver, loss of tissue, cirrhosis
-not inherited
What are the two types of biliary atresia? - (answers)fetal- noted in womb (other defects like
heart, spleed, intestines)
perinatal- appears 2-4 weeks after birth
What causes biliary atresia? - (answers)-infection after birth (cytomegalovirus or rotavirus)
-autoimmune disorder
-developmental issue in womb
-exposure to toxic substances
What are symptoms of biliary atresia? - (answers)jaundice
dark urine
light to white stools
poor wt gain and growth
, How do you diagnose biliary atresia? - (answers)any infant with jaundice present 2-3 weeks after
birth
-direct and indirect serum bilirubin
-LFTs
-abdominal x-ray
-abdominal US
-liver bx
How do you treat biliary atresia? - (answers)surgery (Kasai procedure)
liver transplant
What are risk factors for dehydration? - (answers)GI virus
vomiting/diarrhea
What are s/sx of dehydration? - (answers)sunken anterior fontanel
tachycardia and decrease cap refill
decrease urine output is sensitive but nonspecific
increase in urine specific gravity
decrease BP- late finding=more than 10% fluid loss