IHS 340 Practice Exam Revision Questions And Answers Verified 100% Correct

IHS 340 Practice Exam Revision Questions And Answers Verified 100% Correct The specific molecular structure on an antigen that is specifically bound by an antibody is called _________. (A) an immunoglobulin (B) a heavy chain (C) an epitope (D) a cross-reactive ligand (E) a MAMP (or PAMP) - ANSWER C) epitope The cell surface receptors that bind the constant region of an antibody molecule and provides additional functions to an antibody molecule are called ___________. (A) cytokine receptors (B) Fc receptors (C) co-stimulatory molecules (D) degenerate receptors (E) MHC molecules - ANSWER B) Fc receptors 13. B cells are a type of _________ cell. (A) lymphoid (B) myeloid (C) erythroid - ANSWER A) lymphoid cell 14. A leukocyte is a ___________. (A) Cell (B) Receptor (C) Signal molecule (D) Gene - ANSWER A) cell 15. Which of the following statements is/are TRUE? I. Many airborne allergens possess enzymatic activity that damage the epithelium II. Epithelial damage can lead to the production of IL-33 or IL-25 by the epithelium that can activate ILC2 cells in the underlying tissue (A) Only I is true. (B) Only II is true. (C) Both I & II are true. (D) Both I & II are false. - ANSWER (C) Both I & II are true. Which of the following statements is/are TRUE? I. Mast cells are activated by antigen cross-linking of the IgE bound by FceR on their surface. II. Mast cell activation results in the rapid release of its granules which contain vasoactive amines such as histamine. (A) Only I is true. (B) Only II is true. (C) Both I & II are true. (D) Both I & II arefalse. - ANSWER (C) Both I & II are true. Which one of the following cytokines are NOT produced in significant amounts by Th2 cells? (A) IL-4 (B) IL-5 (C) IL-12 (D) IL-13 - ANSWER C) IL-12 Which one of the following types of cells cause allergy symptoms and inflammation by degranulation? A) dendritic cells B) lymphocytes C) macrophage D) mast cells - ANSWER D) mast cells 19. Anaphylaxis is the most severe form of an allergic response because __________. (A) it is mediated by IgE (B) peanuts are the allergen (C) it involves activation and degranulation of mast cells throughout the body (D) it can never be slowed/stopped by injectable epinephrine or intravenous fluids - ANSWER (C) it involves activation and degranulation of mast cells throughout the body Omalizumab is an IgE-specific monoclonal antibody that is being used a biotherapeutic in treating allergic diseases. It functions by ___________. (A) binding to the constant region of IgE molecules and preventing interactions with the high affinity IgE FcR on mast cells, basophils and eosinophils (B) binding to the variable region of allergen-specific IgE molecules and blocking the allergen from binding , (C) killing cells in the body that express the high affinity IgE FcR, such as mast cells basophils and eosinophils - ANSWER (A) binding to the constant region of IgE molecules and preventing interactions with the high affinity IgE FcR on mast cells, basophils and eosinophils Dendritic cells present extracellular-acquired antigen to which type of cell? A) epithelial cells B) mast cell C) B cell D) T cell E) macrophage - ANSWER D) t cell Which of the following is NOT a characteristic of a cytokine? (A) it is a protein produced by infectious agents, such as bacteria (B) it binds to a specific receptor on host cells (C) it is an intercellular signaling molecule (D) it can act locally or systemically (E) it can have multiple effects, depending on the target cell - ANSWER (A) it is a protein produced by infectious agents, such as bacteria Which one of the following cells is the primary source of cytokine signals to activate B cells for isotype switching? (A) Dendritic cell (B) Tc cell (C) Th cell (D) Macrophage (E) Monocyte - ANSWER C) Th cell How many biochemically distinct types of epitopes will a single IgE antibody molecule bind to?