Verified Answers (100% Correct Answers) Already
Graded A+
Quiz: cancer is the ______ leading cause of death in the, Ans: second ; behind
heart disease
Quiz: most common type of cancer in men?, Ans: prostate
Quiz: most common type of cancer in women?, Ans: breast
Quiz: T or F: plants can have tumors, Ans: TRUE
Quiz: two types of DNA damage that can lead to mutations that can lead to
cancer:, Ans: 1. internal : intermediates of metabolism (free radicals), DNA
replication errors
2. external : sunlight, carcinogens, ionizing radiation
Quiz: about how many cells at any point are actively undergoing mitosis?,
Ans: approx. 20%
Quiz: different checkpoints for cell cycle:, Ans: 1. cell growth checkpoint
(during the end of phase G1; checks that cell has grown enough & has made
the proper proteins for the synthesis phase) if not cell goes to G0 phase
© 2025 Get it right Stuvia US All rights reserved
, 2. DNA synthesis checkpoint: occurs during synthesis (S phase); checks
whether DNA has been correctly replicated
3. mitosis checkpoint: occurs during mitosis phase (M phase); checks whether
mitosis is complete, if so cell divides and then works to repeat the whole
process
Quiz: what is notable about the START checkpoint?, Ans: once cells have
passed START, they are committed to enter the S phase and replicate their
DNA
Quiz: T or F: progression thru the cell cycle is regulated by external and
internal signals, Ans: TRUE
Quiz: what does ERKs stand for?, Ans: Extracellular signal-Regulated protein
Kinases
Quiz: how does the MAPK/Ras pathway work?, Ans: ultimately ERK-1 enters
the nucleus and activates transcription factors that lead to the expression of
Cyclin D-1
Quiz: what goes wrong in the MAPK/Ras pathway that leads to cancer?, Ans:
- can be a loss of control over cell division --> a mutation in the pathway can
lead to the pathway always being on, which results in cells dividing indefinitely
; cyclin D-1 is continuously made which activates the cell cycle to occur
© 2025 Get it right Stuvia US All rights reserved