NSG 531 Advanced Pharmacology
Exam 3 Questions With Correct
Answers Latest Updated
2024/2025 Graded A+.
Save
Terms in this set (99)
What are the Depolarization (0), partial
phases of a non- repolarization (1), plateau (2),
pacemaker repolarization (3), and resting
action membrane potential (4).
potential?
Resting membrane potential (-90 to
Phase 4 of a
-70mV). Cell is polarized with Na+
non-pacemaker
and Ca2+ channels closed and K+
action potential.
channels open.
, Depolarization caused by currents
Phase 0 of a from adjacent cells. When threshold
non-pacemaker (-40mV) is met, fast voltage-gated
action potential. Na+ channels open and K+ channels
close, causing rapid depolarization.
Partial repolarization. All channels
Phase 1 of a
are closed except for K+, which
non-pacemaker
starts the repolarization process as
action potential.
K+ leaves the cell.
Phase 2 of a Plateau. Influx of Ca2+ through L-
non-pacemaker type Ca2+ channels is electrically
action potential. balanced by K+ efflux.
Repolarization. Ca2+ channels are
Phase 3 of a closed but K+ channels remain
non-pacemaker open, making the inside of the
action potential. myocyte more and more negative
until the cell is fully repolarized.
During which Phases 0, 1, 2, and part of the Phase
phases of a non- 3. Refractory periods limit the
pacemaker frequency of cardiac contractions,
action potential prevent arrythmias, and allow of
is the myocyte adequate filling during diastole.
refractory to a
new stimulus?
,Compared to true resting potential; pacemaker
the non- cells generate regular, spontaneous
pacemaker action potentials through slow,
myocytes, cells inward Ca2+ currents.
within the SA
node have no
_________ .
What are the Depolarization (0), repolarization
phases of a (3), and slow depolarization (4)
pacemaker
action
potential?
Phase 0 of a Depolarization. Voltage-gated L-
pacemaker type Ca2+ channels are open, and
action potential. Ca2+ rushes in.
Repolarization. Voltage-gated K+
Phase 3 of a
channels open in response to the
pacemaker
positive current (+10mV) and K+
action potential.
leaves the cell.
, Slow depolarization. Funny voltage-
gated Na+ channels open for a
short time at a voltage of -60mV to
bring the voltage up to -50mV, at
Phase 4 of a which point they close and the T-
pacemaker type (transient) Ca2+ channel
action potential. opens. T-type Ca2+ channels cause
the influx of Ca2+ that brings to cell
up to about -40mV, and then
threshold is met again for
depolarization.
In states of hypoxia, when lack of
oxygen creates a "less negative"
When do non-
RMP (-50mV instead of -90mV)
pacemaker cells
through disruption of the Na+/K+
take over as
ATPase pump. Non-pacemaker cells
pacemaker
take over using Ca2+ to carry a
cells?
depolarizing current (fast Na+
channels close at -50mV).
Exam 3 Questions With Correct
Answers Latest Updated
2024/2025 Graded A+.
Save
Terms in this set (99)
What are the Depolarization (0), partial
phases of a non- repolarization (1), plateau (2),
pacemaker repolarization (3), and resting
action membrane potential (4).
potential?
Resting membrane potential (-90 to
Phase 4 of a
-70mV). Cell is polarized with Na+
non-pacemaker
and Ca2+ channels closed and K+
action potential.
channels open.
, Depolarization caused by currents
Phase 0 of a from adjacent cells. When threshold
non-pacemaker (-40mV) is met, fast voltage-gated
action potential. Na+ channels open and K+ channels
close, causing rapid depolarization.
Partial repolarization. All channels
Phase 1 of a
are closed except for K+, which
non-pacemaker
starts the repolarization process as
action potential.
K+ leaves the cell.
Phase 2 of a Plateau. Influx of Ca2+ through L-
non-pacemaker type Ca2+ channels is electrically
action potential. balanced by K+ efflux.
Repolarization. Ca2+ channels are
Phase 3 of a closed but K+ channels remain
non-pacemaker open, making the inside of the
action potential. myocyte more and more negative
until the cell is fully repolarized.
During which Phases 0, 1, 2, and part of the Phase
phases of a non- 3. Refractory periods limit the
pacemaker frequency of cardiac contractions,
action potential prevent arrythmias, and allow of
is the myocyte adequate filling during diastole.
refractory to a
new stimulus?
,Compared to true resting potential; pacemaker
the non- cells generate regular, spontaneous
pacemaker action potentials through slow,
myocytes, cells inward Ca2+ currents.
within the SA
node have no
_________ .
What are the Depolarization (0), repolarization
phases of a (3), and slow depolarization (4)
pacemaker
action
potential?
Phase 0 of a Depolarization. Voltage-gated L-
pacemaker type Ca2+ channels are open, and
action potential. Ca2+ rushes in.
Repolarization. Voltage-gated K+
Phase 3 of a
channels open in response to the
pacemaker
positive current (+10mV) and K+
action potential.
leaves the cell.
, Slow depolarization. Funny voltage-
gated Na+ channels open for a
short time at a voltage of -60mV to
bring the voltage up to -50mV, at
Phase 4 of a which point they close and the T-
pacemaker type (transient) Ca2+ channel
action potential. opens. T-type Ca2+ channels cause
the influx of Ca2+ that brings to cell
up to about -40mV, and then
threshold is met again for
depolarization.
In states of hypoxia, when lack of
oxygen creates a "less negative"
When do non-
RMP (-50mV instead of -90mV)
pacemaker cells
through disruption of the Na+/K+
take over as
ATPase pump. Non-pacemaker cells
pacemaker
take over using Ca2+ to carry a
cells?
depolarizing current (fast Na+
channels close at -50mV).
