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Real NCLEX-RN & HESI Exit Exam 2025 Practice | Authentic Critical Thinking Questions with Rationales

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This expertly curated NCLEX-RN study resource features critical-thinking practice questions aligned with the latest HESI/NCLEX exam standards. Every question includes detailed rationales to boost clinical judgment, nursing prioritization, and patient safety decision-making. Updated for the 2025–2026 testing cycle, this content covers essential nursing domains—medical-surgical, pharmacology, maternity, pediatrics, mental health, and leadership. Ideal for nursing students preparing for the NCLEX-RN, HESI Exit Exam, ATI, or other professional exams.

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1




Page | 1




NCLEX-Style Comprehensive Practice Test

Bank Updated for 2025–2026 |

HESI/NCLEX RN Format | Critical

Thinking Focused

, 2




QUESTION 1

Page | 2 A nurse is caring for a postoperative client who underwent abdominal surgery 2 hours ago.

The client is alert and oriented but reports increasing pain at the surgical site. Vital signs are:

BP 136/84 mmHg, HR 110 bpm, RR 22/min, Temp 99.4°F. The nurse notes the abdominal

dressing is dry and intact. Which of the following actions should the nurse take first?


A) Notify the healthcare provider of the increased pain

B) Reassess the client's pain level in 30 minutes

✔✔✔ Correct Answer > C) Perform a full pain assessment including location, quality, and

intensity

D) Administer a PRN dose of acetaminophen for pain


Rationale: Before intervening or notifying the provider, the nurse must perform a complete

pain assessment to determine appropriate interventions and evaluate whether the pain is

expected or a sign of complication.




QUESTION 2

A nurse is reviewing lab results for a client receiving chemotherapy for leukemia. The

client’s WBC count is 2,000/mm³, platelets are 75,000/mm³, and hemoglobin is 8.5 g/dL. The

nurse should implement which of the following precautions based on this data?


A) Seizure precautions

B) Contact precautions

, 3


✔✔✔ Correct Answer > C) Neutropenic precautions

D) Droplet precautions


Page | 3 Rationale: A WBC count of 2,000/mm³ indicates severe neutropenia, placing the client at

high risk for infection. Neutropenic precautions, including reverse isolation and limiting

visitors, are required.




QUESTION 3

A nurse is assessing a client admitted with acute pancreatitis. The client reports severe

abdominal pain radiating to the back, nausea, and vomiting. The abdomen is tender and

distended. Which laboratory value is most indicative of this condition?


A) Elevated BUN

B) Decreased albumin

✔✔✔ Correct Answer > C) Elevated serum lipase

D) Increased bilirubin


Rationale: Serum lipase is the most specific and sensitive marker for pancreatitis. Elevated

levels confirm the diagnosis.




QUESTION 4

A nurse is caring for a 78-year-old client with Alzheimer’s disease who is frequently

wandering at night and attempting to leave the facility. Which of the following is the most

appropriate nursing intervention?

, 4


A) Restrain the client to prevent injury

B) Keep the client in bed with all four side rails up

C) Administer a sedative at bedtime
Page | 4
✔✔✔ Correct Answer > D) Implement a motion sensor and frequent rounds during the

night


Rationale: Using non-restrictive safety measures such as motion sensors and close

monitoring preserves dignity and reduces fall/injury risk. Restraints and sedation should be

avoided unless all alternatives fail.




QUESTION 5

A nurse is preparing to administer furosemide 40 mg IV to a client with congestive heart

failure. Which of the following assessments is most important to perform before

administration?


A) Respiratory rate

B) Pupillary reaction

C) Skin turgor

✔✔✔ Correct Answer > D) Serum potassium level


Rationale: Furosemide is a loop diuretic that can cause hypokalemia. Monitoring serum

potassium prior to administration is critical to avoid life-threatening arrhythmias.

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Welcome to HealthStudyPro – Your 24/7 Partner for Nursing & Healthcare Exam Success! At HealthStudyPro, we provide premium, A+ rated study materials to help nursing and healthcare students excel in their exams. Whether you're preparing for the HESI RN Exit Exam, ATI, NCLEX, or other critical assessments, we’ve got you covered with accurate, up-to-date, and verified resources.

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