2026 50 Questions and 100% Verified Correct
Answers Guaranteed A+
How is glycolysis controlled in the liver? - CORRECT ANSWER: - store glucose as
glycogen
- release glucose into blood
- generate reducing power of biosynthesis
- synthesize biochemicals
In phosphofructokinase, activity is enhanced by high levels of AMP and ADP. Why
AMP? - CORRECT ANSWER: very sensitive to small changes in ATP concentration
Is glycolysis aerobic or anaerobic? - CORRECT ANSWER: anaerobic
Metabolically, it's logical for phosphofructokinase activity to be... - CORRECT ANSWER:
increased as AMP levels rise
Properties of glucokinase? - CORRECT ANSWER: - not inhibited by G-6P
- 50 fold lower affinity for glucose
Regulation of glycolysis: hexokinase in muscles - CORRECT ANSWER: - inhibited by
product (G6P)
- hexokinase is inhibited when phosphofructokinase is inhibited because F6P builds up
causing G6P to build up (1st irreversible step)
Regulation of glycolysis: hexokinase in the liver - CORRECT ANSWER: - inhibited by
product (G6P)
, Regulation of glycolysis: phosphofructokinase in muscles (what enhances and inhibits
the activity?) - CORRECT ANSWER: - activity is inhibited by high levels of ATP (plenty
of energy supply, don't burn glucose to make more!)
- affinity for F6P is lowered
- activity is enhanced by high levels of AMP and ADP (energy supply is low, burn
glucose and make more ATP!)
- reverses the action of ATP
- activity is inhibited by low pH (Whoa, pH is dropping fast under the current metabolic
conditions - slow down glycolysis!)
Regulation of glycolysis: phosphofructokinase in the liver
(what is it enhanced by?) - CORRECT ANSWER: activity is enhanced by fructose 2,6-
bisphosphate (glucose and fructose are high, let's store some energy) (F2, 6BP is a
measure of blood glucose levels)
Regulation of glycolysis: phosphofructokinase in the liver - CORRECT ANSWER: - have
lower ATP
- increased AMP/ADP
- pH is not really a factor
Regulation of glycolysis: phosphofructokinase in the liver (what is it inhibited by?) -
CORRECT ANSWER: activity is inhibited by citrate (in conjunction with ATP)
Regulation of glycolysis: pyruvate kinase in the liver - CORRECT ANSWER: - lower ATP
- increased AMP
- increased F-1, 6-BP
- decreased alanine