2025
AANP Family Nurse Practitioner Exam Questions 2025 –
200+ Verified Practice Questions with Rationales |
Primary Care, Health Promotion, Pharmacology &
Clinical Scenarios | AANP FNP Board Exam Prep Guide
,AANP Exam Questions
A patient tells the nurse practitioner that she recently started taking the supplement St. John's
wort after reading about its benefits online. Which of the following medications, if being actively
consumed, must be immediately stopped?
A. Benadryl
B. Famotidine (Pepcid)
C. Metformnin (Glucophage)
D. Sumatriptan (Imitrex)
CORRECT ANSWER ✔✔ D. Sumatriptan (imitrex)
Sumatriptan (Imitrex) (D) is a medication used to treat migraines and belongs to a drug class
known as serotonin agonists. When used in conjunction with St. John's wort, it may increase the
risk of serotonin syndrome, a potentially life-threatening condition.
Which of the following is not a symptom of both major depressive disorder and post-traumatic
stress disorder?
A. Difficulty concentrating
B. Hypervigilance
C. Insomnia
D. Irritabilty
CORRECT ANSWER ✔✔ B. Hypervigilance
In addition to difficulty concentrating, insomnia, and irritability, major depressive disorder
(MDD) may also include symptoms of depressed mood, anhedonia, weight loss or gain, and low
energy. However, hypervigilance (B) is not a symptom associated with this diagnosis.
,A patient with type 1 diabetes presents for a follow-up visit. He has been stable on his
medication regimen but is worried because he is between jobs and will be without health
insurance coverage for a few months. He asks if there are less expensive insulin options to get
him through this time. Which of the following would be good options for this patient, given his
circumstance?
Incorrect
A.
Insulin aspart 70/30
B.
Insulin detemir
C.
Insulin isophane
D.
Insulin degludec
CORRECT ANSWER ✔✔ Insulin Isophane
The least expensive insulin type listed in this question is insulin isophane (C) (neutral protamine
Hagedorn insulin). There are also often pharmacy-specific coupons that can be used on insulin,
so helping patients apply for and navigate these programs can be instrumental in managing their
diabetes. Another inexpensive option is regular insulin.Insulin analogs (glargine, detemir,
degludec, lispro, and aspart) are significantly more expensive than human insulin (isophane,
regular). Insulins modified by manufacturers, especially when sold as brand-name medications,
tend to be more expensive due to this modification. While analogs offer alternate lengths of
action and convenience, there is no well-documented clinical evidence that patient outcomes are
improved with differing brands. Therefore, maintaining a patient's blood glucose level through
outcome-focused treatment is more valuable than a process-focused plan based on medication.
, A 40-year-old woman with type 2 diabetes presents to the clinic with concerns of spiking blood
sugar between lunch and dinner. She states she is on a rapid-acting insulin sliding scale and long-
acting insulin. Which change should be implemented to help prevent or curb this glycemic spike?
A.
Add a dose of mealtime insulin aspart (Novolog) at lunch
B.
Add insulin detemir (Levemir) at night
C.
Increase her insulin glargine (Lantus)
D.
Prescribe a dose of neutral protamine Hagedorn insulin with dinner
CORRECT ANSWER ✔✔ A. Add a dose of mealtime insulin aspart (Novolog) at lunch
Insulin aspart (Novolog) (A) is a rapid acting insulin that is commonly dosed with meals and as a
sliding scale regimen based on a patient's glucose prior to eating (preprandial). It is the
appropriate insulin to add as a mealtime dose when patients experience blood glucose spikes
between meals because of its short-acting properties. Peak time action of insulin aspart is 2 hours
with initial effect within the first 30 minutes, making it an ideal choice to control expected
postprandial glycemic spikes
Which of the following conditions is associated with an increased risk for conductive hearing
loss?
A.
Acoustic neuroma