Development of Mandible
,• The first structure to develop in the primordium of the
lower jaw is the mandibular division of trigeminal nerve
that preceeded the mesenchymal condensation forming
the first arch (mandibular).
• The prior presence of nerve has been postulated as
being necessary to induce osteogenesis by the
production of neutrotrophic factors
, MECKEL’S CARTILAGE
• In human beings, Meckel's cartilage has a close positional
relationship to the developing mandible.
• Meckel’s cartilage is derived from the first branchial arch around the
41st-45th day of intra uterine life.
• It extends from the cartilaginous otic capsule to the midline or
symphysis and provides a template for guiding the growth of the
mandible.
• The two cartilages of each side do not meet at the midline but are
separated by a thin band of mesenchyme.
• The mandibular branch of the trigeminal nerve (the nerve of the first
arch) has a close relationship to Meckel's cartilage, beginning two
thirds of the way along the length of the cartilage.
• At this point the mandibular nerve divides into lingual and inferior
alveolar branches, which run along the medial and lateral aspects of
the cartilage, respectively.
• The inferior alveolar nerve further divides into incisor and mental
branches more anteriorly.
,• The first structure to develop in the primordium of the
lower jaw is the mandibular division of trigeminal nerve
that preceeded the mesenchymal condensation forming
the first arch (mandibular).
• The prior presence of nerve has been postulated as
being necessary to induce osteogenesis by the
production of neutrotrophic factors
, MECKEL’S CARTILAGE
• In human beings, Meckel's cartilage has a close positional
relationship to the developing mandible.
• Meckel’s cartilage is derived from the first branchial arch around the
41st-45th day of intra uterine life.
• It extends from the cartilaginous otic capsule to the midline or
symphysis and provides a template for guiding the growth of the
mandible.
• The two cartilages of each side do not meet at the midline but are
separated by a thin band of mesenchyme.
• The mandibular branch of the trigeminal nerve (the nerve of the first
arch) has a close relationship to Meckel's cartilage, beginning two
thirds of the way along the length of the cartilage.
• At this point the mandibular nerve divides into lingual and inferior
alveolar branches, which run along the medial and lateral aspects of
the cartilage, respectively.
• The inferior alveolar nerve further divides into incisor and mental
branches more anteriorly.
