NCLEX PHARMACOLOGY 2025
TESTBANK
NCLEX Pharmacology 2025 – High-Yield Drug
Guide with Mechanisms, Side Effects, Antidotes &
Rationales | NCLEX-RN/PN Exam Medication
Review with Flashcards & NGN Practice Questions
,NCLEX Pharmacology 2025
SECTION ONE
The client diagnosed with active tuberculosis has been prescribed isoniazid 300 mg by mouth
every day. What should the nurse teach this client?
Select all that apply
1. "Notify your healthcare provider if your urine turns dark."
2. "Your healthcare provider has prescribed B6 along with the isoniazid to prevent neuritis."
3. "You should avoid eating aged cheeses and smoked fish."
4. "Eat foods such as tuna twice a week."
5. "Rise slowly from lying to sitting, or sitting to standing."
1. "Notify your healthcare provider if your urine turns dark."
2. "Your healthcare provider has prescribed B6 along with the isoniazid to prevent neuritis."
3. "You should avoid eating aged cheeses and smoked fish."
5. "Rise slowly from lying to sitting, or sitting to standing."
(1., 2., 3., & 5 Correct: Signs of hepatotoxicity from this medication include dark urine, jaundice,
and clay-colored stool. Isoniazide- induced pyridoxine (Vitamin B6) depletion causes neurotoxic
effects. Vitamin B6 supplementation of 10-50 mg usually accompanies isoniazid use. Aged
cheeses and smoked fish are high in tyramine which may cause palpitations, flushing, and blood
pressure elevation while taking isoniazid. Avoid these foods during treatment. Isoniazid should
be taken on an empty stomach, one hour before or two hours after food. Some clients experience
orthostatic hypotension while taking isoniazid, so caution against rapid positional changes.
4. Incorrect: Histamine containing foods such as tuna and yeast extracts may cause exaggerated
drug response (H/A, hypotension, palpitations sweating, itching, flushing, diarrhea).)
A client diagnosed with new onset atrial fibrillation has been prescribed dabigatran. What should
the nurse teach this client?
Select all that apply
1. Place medication in a weekly pill organizer so that medication is not forgotten.
,2. Do not take with clopidogrel.
3. Dabigatran decreases the risk of stroke associated with atrial fibrillation.
4. Take this medication with food.
5. aPTT and INR levels will be drawn monthly.
2. Do not take with clopidogrel.
3. Dabigatran decreases the risk of stroke associated with atrial fibrillation.
4. Take this medication with food.
(2., 3., & 4. Correct: Do not take dabigatran with any other anticoagulants, including clopidogrel
due to increased bleeding risk. Dabigatran decreases the risk of stroke and systemic embolism in
clients with atrial fibrillation that is not associated with a cardiac valve problem. Take this
medication with food to decrease gastric side effects such as dyspepsia and gastritis. Proton
pump inhibitors and histamine 2 recepter blockers may also decrease gastric side effects.
1. Incorrect: After container is opened, medication should be used within 30 days. It is sensitive
to moisture and should not be stored in weekly pill organizers. To maintain efficacy, keep
medication in manufacturer- supplied bottle.
5. Incorrect: This medication does not require monitoring of INR levels. However, the client
should be informed about the risk of bleeding and to monitor for signs of bleeding.)
A client has a prescription for nitroglycerin gr 1/400 SL prn for angina pain. How many tablets
should the nurse give the client? Use numbers and decimals only.
Nitroglycerin tablets, USP
Rx Only
0.3 mg (1/200 gr)
100 Sublingual Tablets
Ans:______
0.5
(Rationale:
, (0.0025 gr ÷ 1) × (0.3 mg ÷ 0.005 gr) × (1 tab ÷ 0.3 mg) = (0.00075 ÷ 0.0015) = 0.5 tab
Ans: 0.5 tab)
A client has been started on intravenous gentamicin for osteomyelitis. The nurse informs the
client frequent blood work will be done to monitor the amount of medication in the body. The
nurse knows what labs are a priority to check every three days for the client?
1. BUN and creatinine.
2. Liver function studies.
3. Hemoglobin and hematocrit.
4. Peak and trough levels.
4. Peak and trough levels.
(4. Correct: Peak and trough levels help to determine the amount of medication in the body
system at specific times. Gentamicin is a very potent antibiotic; therefore, it is crucial to keep
track of blood levels of this medication. Too low a level of this drug would be ineffective against
the bacteria while too high a level increases the potential for severe side effects or toxicity from
this antibiotic.
1. Incorrect: Because aminoglycosides such as gentamicin can lead to nephrotoxicity, checking
BUN and creatinine levels periodically is important. However, it would not be necessary to
check those values every three days.
2. Incorrect: Aminoglycosides like gentamicin rarely affect the liver; therefore, liver function
studies would not be needed frequently.
3. Incorrect: Hemoglobin and hematocrit levels are rarely impacted by aminoglycosides such as
gentamicin. Although an initial level may be obtained prior to treatment, additional levels are not
necessary.)
The nurse is preparing to give a client's prescribed furosemide dose. How many mL will the
nurse give to the client? Answer to the first decimal place. Answer with numbers and decimal
only.
Perscription:
Furosemide 25 mg by mouth daily
TESTBANK
NCLEX Pharmacology 2025 – High-Yield Drug
Guide with Mechanisms, Side Effects, Antidotes &
Rationales | NCLEX-RN/PN Exam Medication
Review with Flashcards & NGN Practice Questions
,NCLEX Pharmacology 2025
SECTION ONE
The client diagnosed with active tuberculosis has been prescribed isoniazid 300 mg by mouth
every day. What should the nurse teach this client?
Select all that apply
1. "Notify your healthcare provider if your urine turns dark."
2. "Your healthcare provider has prescribed B6 along with the isoniazid to prevent neuritis."
3. "You should avoid eating aged cheeses and smoked fish."
4. "Eat foods such as tuna twice a week."
5. "Rise slowly from lying to sitting, or sitting to standing."
1. "Notify your healthcare provider if your urine turns dark."
2. "Your healthcare provider has prescribed B6 along with the isoniazid to prevent neuritis."
3. "You should avoid eating aged cheeses and smoked fish."
5. "Rise slowly from lying to sitting, or sitting to standing."
(1., 2., 3., & 5 Correct: Signs of hepatotoxicity from this medication include dark urine, jaundice,
and clay-colored stool. Isoniazide- induced pyridoxine (Vitamin B6) depletion causes neurotoxic
effects. Vitamin B6 supplementation of 10-50 mg usually accompanies isoniazid use. Aged
cheeses and smoked fish are high in tyramine which may cause palpitations, flushing, and blood
pressure elevation while taking isoniazid. Avoid these foods during treatment. Isoniazid should
be taken on an empty stomach, one hour before or two hours after food. Some clients experience
orthostatic hypotension while taking isoniazid, so caution against rapid positional changes.
4. Incorrect: Histamine containing foods such as tuna and yeast extracts may cause exaggerated
drug response (H/A, hypotension, palpitations sweating, itching, flushing, diarrhea).)
A client diagnosed with new onset atrial fibrillation has been prescribed dabigatran. What should
the nurse teach this client?
Select all that apply
1. Place medication in a weekly pill organizer so that medication is not forgotten.
,2. Do not take with clopidogrel.
3. Dabigatran decreases the risk of stroke associated with atrial fibrillation.
4. Take this medication with food.
5. aPTT and INR levels will be drawn monthly.
2. Do not take with clopidogrel.
3. Dabigatran decreases the risk of stroke associated with atrial fibrillation.
4. Take this medication with food.
(2., 3., & 4. Correct: Do not take dabigatran with any other anticoagulants, including clopidogrel
due to increased bleeding risk. Dabigatran decreases the risk of stroke and systemic embolism in
clients with atrial fibrillation that is not associated with a cardiac valve problem. Take this
medication with food to decrease gastric side effects such as dyspepsia and gastritis. Proton
pump inhibitors and histamine 2 recepter blockers may also decrease gastric side effects.
1. Incorrect: After container is opened, medication should be used within 30 days. It is sensitive
to moisture and should not be stored in weekly pill organizers. To maintain efficacy, keep
medication in manufacturer- supplied bottle.
5. Incorrect: This medication does not require monitoring of INR levels. However, the client
should be informed about the risk of bleeding and to monitor for signs of bleeding.)
A client has a prescription for nitroglycerin gr 1/400 SL prn for angina pain. How many tablets
should the nurse give the client? Use numbers and decimals only.
Nitroglycerin tablets, USP
Rx Only
0.3 mg (1/200 gr)
100 Sublingual Tablets
Ans:______
0.5
(Rationale:
, (0.0025 gr ÷ 1) × (0.3 mg ÷ 0.005 gr) × (1 tab ÷ 0.3 mg) = (0.00075 ÷ 0.0015) = 0.5 tab
Ans: 0.5 tab)
A client has been started on intravenous gentamicin for osteomyelitis. The nurse informs the
client frequent blood work will be done to monitor the amount of medication in the body. The
nurse knows what labs are a priority to check every three days for the client?
1. BUN and creatinine.
2. Liver function studies.
3. Hemoglobin and hematocrit.
4. Peak and trough levels.
4. Peak and trough levels.
(4. Correct: Peak and trough levels help to determine the amount of medication in the body
system at specific times. Gentamicin is a very potent antibiotic; therefore, it is crucial to keep
track of blood levels of this medication. Too low a level of this drug would be ineffective against
the bacteria while too high a level increases the potential for severe side effects or toxicity from
this antibiotic.
1. Incorrect: Because aminoglycosides such as gentamicin can lead to nephrotoxicity, checking
BUN and creatinine levels periodically is important. However, it would not be necessary to
check those values every three days.
2. Incorrect: Aminoglycosides like gentamicin rarely affect the liver; therefore, liver function
studies would not be needed frequently.
3. Incorrect: Hemoglobin and hematocrit levels are rarely impacted by aminoglycosides such as
gentamicin. Although an initial level may be obtained prior to treatment, additional levels are not
necessary.)
The nurse is preparing to give a client's prescribed furosemide dose. How many mL will the
nurse give to the client? Answer to the first decimal place. Answer with numbers and decimal
only.
Perscription:
Furosemide 25 mg by mouth daily
