Exam 2 Latest Update 2025-2026 150 Questions
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Aminoglycosides block protein production and consist of which antibiotics? - CORRECT
ANSWER: gentamicin, streptomycin, tobramycin
Anti-depressant that is to be used with caution in cardiac patients due to behaving like
class 1 anti-arrythmics? - CORRECT ANSWER: TCAs
Are cephalosporins bactericidal or bacteriostatic? - CORRECT ANSWER: Bacteriocidal
Are PCNs bactericidal or bactriostatic? - CORRECT ANSWER: Bactericidal
Are sulfonamides bacteriocidal or bacteriostatic? - CORRECT ANSWER: Bacteriostatic
Are tetracyclines bacteriostatic or bacteriocidal? - CORRECT ANSWER: bacteriostatic
Are tetracyclines broad or narrow in spectruM? - CORRECT ANSWER: Broad and they
have a lot of resistance issues
Benzodiazepines affect what neurotransmitter and how? - CORRECT ANSWER:
Increases the effects of GABA
Can valproate (Depakote) be used during pregnancy? - CORRECT ANSWER: It is a
known teratogen. If needed, must be used after 1st trimester.
,Do cephalosporins become more broad or narrow in spectrum as you go up in
generation? - CORRECT ANSWER: More broad spectrum
Does Lithium have a broad or narrow therapeutic range? - CORRECT ANSWER:
Narrow therapeutic range; toxicity may show nausea and drowsiness
How and when is silver sulfadiazine used? - CORRECT ANSWER: Used for burns, but
its usefulness is poor
How are acyclovir and valcyclovir metabolized? - CORRECT ANSWER: 10% by the
liver and 90% by the kidneys
How are sexual side effects linked to SSRIs? - CORRECT ANSWER: Sexual side
effects may start after 1 month; especially common in Paxil
How do anti-TB drugs work? - CORRECT ANSWER: They inhibit the formation of
mycolic acids which are an important part of the cell wall
How do anti-virals (neuramidase inhibitors) work? - CORRECT ANSWER: These
medications break the bond that attaches the viral particles to the host cell and keeps
them from replicating
How do anti-virals for HSV and VZV work? - CORRECT ANSWER: They block an
enzyme that is essential in the production of new viruses so they can't replicate
How do SSRIs work? - CORRECT ANSWER: They block the reuptake of serotonin at
the synaptic cleft so there is more serotonin around
How do you discontinue an SSRI? - CORRECT ANSWER: Taper by reducing the dose
by 50% for 3-4 days
, How does antibiotic resistance occur? - CORRECT ANSWER: 1. Natural by genetic
mutations
2. Spontaneous by random mutations
3. Build up over time or by misuse of antibiotics
How does carbamazepine work? - CORRECT ANSWER: Works by decreasing nerve
impulses that cause seizures and pain
How does doxycline affect OCPs? - CORRECT ANSWER: Little evidence has shown
that it does affect OCPs, but a second method of protection should be used
How does ethambutol work as an anti-TB drug? - CORRECT ANSWER: It inhibits the
sythesis of mycelic acids which is an important part of the cell wall
How does Lithium act as a mood stabilizer? - CORRECT ANSWER: It replaces sodium
during depolarization so it stops the transmission of electrical impulses
How does phentermine work? - CORRECT ANSWER: Treats obesity by decreasing the
hunger perception and releases NE an EPI which breaks down stored fat = lose weight
How does pyrazinamide (PZA) act on bacteria? - CORRECT ANSWER: It is largely
bacteriostatic, but can be bacteriocidal in actively replicating bacteria
How is clarithromycin excreted? - CORRECT ANSWER: It is excreted by BOTH the liver
and the kidneys so dose adjustments are not required in patients with impaired liver
function
How is the gram coverage in Cephalosporins? - CORRECT ANSWER: 1st generation
are gram positive and as you go up in generations, you lose gram positive coverage
and more gram negative