6/27/25, 8:23
AM
NSG 533 ADVANCED PHARMACOLOGY TEST 1 WEEK 4 EXAM
QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS
VERIFIED LATEST UPDATE 2025/2026
Which of the following C
SSRIs requires up to a
5-week washout
period because of the
long half-life of its
potent active
metabolite?
A. Escitalopram
B. Fluvoxamine
C. Fluoxetine
D. Sertraline
Which of the following D
symptoms is most likely
to improve within
approximately 1 week
of starting treatment?
A. Depressed mood
B. Suicidal thoughts
C. Anhedonia
D. Sleep
Of the following B
combinations of
medications, which one
would you want to
avoid?
A. Fluoxetine-lithium
B. Fluoxetine-phenelzine
C. Citalopram-valproic acid
D. Citalopram-aripiprazole
1/32
,6/27/25, 8:23
AM
A 26-year-old man with a D
history of
depression has been
taking sertraline 200
mg/day for 12 weeks
with no response. The
patient has no other
complications. The
physician asks for your
recommendation.
The most reasonable
recommendation would
be to:
A. Increase sertraline
B. Add fluoxetine
C. Switch to amitriptyline
D. Change to venlafaxine
E. Decrease sertraline
Which of the following is C
a dangerous
combination?
A. MAOI-lorazepam
B. MAOI-acetaminophen
C. MAOI-meperidine
D. MAOI-ziprasidone
2/32
,6/27/25, 8:23
AM
A 23-year-old married B
white woman comes to
the outpatient
psychiatric clinic
complaining of
decreased sleep,
decreased appetite,
decreased
concentration,
depressed
mood, thoughts of death,
and lack of
interest in activities for 6
weeks' duration.
She has
no history of
psychiatric illness and
takes no medications
except for Ortho-Tri
Cyclen Lo
daily. Based upon the
patients symptoms,
choose the best
medication to treat
this patient.
A. Nefazodone 100 mg po
twice daily
B. Paroxetine 20 mg po
daily
C. St. John's wort 300
mg po three times
daily
D.Amitriptyline 25 mg at
bedtime
3/32
, 6/27/25, 8:23
AM
A 36-year-old man is D
admitted to the
hospital for a severe
methicillin-resistant
Staphylococcus
aureus diabetic foot
infection and is started
on linezolid 600 mg IV
every 12 hours. His
medication profile
includes paroxetine 40
mg every morning,
trazodone 100 mg at
bedtime as needed for
sleep, and metformin
1000 mg po twice daily.
After 3
days on these
medications, the patient
becomes agitated,
confused, and
diaphoretic and develops
myoclonic jerks.
Which of the following is
the most likely
diagnosis?
A. Overdose of
metformin
B. Bacterial meningitis
C. Neuroleptic malignant
syndrome
D. Serotonin syndrome
A 46-year-old woman B
presents to the
psychiatric outpatient
clinic for follow-up
4/32
AM
NSG 533 ADVANCED PHARMACOLOGY TEST 1 WEEK 4 EXAM
QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS
VERIFIED LATEST UPDATE 2025/2026
Which of the following C
SSRIs requires up to a
5-week washout
period because of the
long half-life of its
potent active
metabolite?
A. Escitalopram
B. Fluvoxamine
C. Fluoxetine
D. Sertraline
Which of the following D
symptoms is most likely
to improve within
approximately 1 week
of starting treatment?
A. Depressed mood
B. Suicidal thoughts
C. Anhedonia
D. Sleep
Of the following B
combinations of
medications, which one
would you want to
avoid?
A. Fluoxetine-lithium
B. Fluoxetine-phenelzine
C. Citalopram-valproic acid
D. Citalopram-aripiprazole
1/32
,6/27/25, 8:23
AM
A 26-year-old man with a D
history of
depression has been
taking sertraline 200
mg/day for 12 weeks
with no response. The
patient has no other
complications. The
physician asks for your
recommendation.
The most reasonable
recommendation would
be to:
A. Increase sertraline
B. Add fluoxetine
C. Switch to amitriptyline
D. Change to venlafaxine
E. Decrease sertraline
Which of the following is C
a dangerous
combination?
A. MAOI-lorazepam
B. MAOI-acetaminophen
C. MAOI-meperidine
D. MAOI-ziprasidone
2/32
,6/27/25, 8:23
AM
A 23-year-old married B
white woman comes to
the outpatient
psychiatric clinic
complaining of
decreased sleep,
decreased appetite,
decreased
concentration,
depressed
mood, thoughts of death,
and lack of
interest in activities for 6
weeks' duration.
She has
no history of
psychiatric illness and
takes no medications
except for Ortho-Tri
Cyclen Lo
daily. Based upon the
patients symptoms,
choose the best
medication to treat
this patient.
A. Nefazodone 100 mg po
twice daily
B. Paroxetine 20 mg po
daily
C. St. John's wort 300
mg po three times
daily
D.Amitriptyline 25 mg at
bedtime
3/32
, 6/27/25, 8:23
AM
A 36-year-old man is D
admitted to the
hospital for a severe
methicillin-resistant
Staphylococcus
aureus diabetic foot
infection and is started
on linezolid 600 mg IV
every 12 hours. His
medication profile
includes paroxetine 40
mg every morning,
trazodone 100 mg at
bedtime as needed for
sleep, and metformin
1000 mg po twice daily.
After 3
days on these
medications, the patient
becomes agitated,
confused, and
diaphoretic and develops
myoclonic jerks.
Which of the following is
the most likely
diagnosis?
A. Overdose of
metformin
B. Bacterial meningitis
C. Neuroleptic malignant
syndrome
D. Serotonin syndrome
A 46-year-old woman B
presents to the
psychiatric outpatient
clinic for follow-up
4/32
