Test Bank for Lehne's Pharmacotherapeutics for Advanced
Practice Nurses and Physician Assistants 3rd Edition by
Resenthal and Burchum
,Chapter 1: Prescriptive Authority
MULTIPLE CHOICE
1. An APRN works at an orthopedic clinic where state law allows prescribing without physician
oversight. How should the APRN’s prescribing authority be classified?
a. Complete authority
b. Independent authority
c. Unrestricted authority
d. Restricted authority
Correct Answer: B
Rationale: The APRN is not legally required to be supervised by a physician, which constitutes
independent prescriptive authority. "Complete" and "unrestricted" are not standard legal
terms.
DIF: Comprehension
REF: p. 1
TOP: Nursing Process: Implementation
MSC: NCLEX Category: Physiologic Integrity; Pharmacological and Parenteral Therapies
Chapter 2: Pharmacokinetics & Pharmacodynamics
MULTIPLE CHOICE
2. A drug with a high first-pass effect will most likely require:
a. No dosage adjustment
b. Increased oral dose
,c. Decreased oral dose
d. Parenteral administration
Correct Answer: D
Rationale: A high first-pass effect significantly reduces bioavailability, often necessitating
parenteral routes to ensure adequate serum concentrations.
DIF: Application
REF: p. 25
TOP: Pharmacokinetics
MSC: NCLEX Category: Physiologic Integrity; Pharmacological and Parenteral Therapies
Chapter 3: Autonomic Nervous System Medications
MULTIPLE CHOICE
3. A patient on a nonselective β-blocker reports shortness of breath. The APRN should suspect:
a. Bronchoconstriction
b. Bradycardia
c. Hypotension
d. Hyperglycemia
Correct Answer: A
Rationale: Nonselective β-blockers block β2 receptors in the lungs, leading to
bronchoconstriction; bradycardia and hypotension may occur but do not explain dyspnea;
hyperglycemia is unrelated.
DIF: Application
REF: p. 72
, TOP: Pharmacodynamics
MSC: NCLEX Category: Physiologic Integrity; Pharmacological and Parenteral Therapies
Chapter 4: Anti-Infective Agents
MULTIPLE CHOICE
4. Which antibiotic requires therapeutic drug monitoring due to nephrotoxicity and
ototoxicity risk?
a. Azithromycin
b. Vancomycin
c. Amoxicillin
d. Ciprofloxacin
Correct Answer: B
Rationale: Vancomycin requires periodic serum level checks to avoid toxicity; other options
rarely necessitate monitoring.
DIF: Analysis
REF: p. 134
TOP: Nursing Process: Implementation
MSC: NCLEX Category: Physiologic Integrity; Pharmacological and Parenteral Therapies
Chapter 5: Cardiovascular Drugs
MULTIPLE CHOICE
Practice Nurses and Physician Assistants 3rd Edition by
Resenthal and Burchum
,Chapter 1: Prescriptive Authority
MULTIPLE CHOICE
1. An APRN works at an orthopedic clinic where state law allows prescribing without physician
oversight. How should the APRN’s prescribing authority be classified?
a. Complete authority
b. Independent authority
c. Unrestricted authority
d. Restricted authority
Correct Answer: B
Rationale: The APRN is not legally required to be supervised by a physician, which constitutes
independent prescriptive authority. "Complete" and "unrestricted" are not standard legal
terms.
DIF: Comprehension
REF: p. 1
TOP: Nursing Process: Implementation
MSC: NCLEX Category: Physiologic Integrity; Pharmacological and Parenteral Therapies
Chapter 2: Pharmacokinetics & Pharmacodynamics
MULTIPLE CHOICE
2. A drug with a high first-pass effect will most likely require:
a. No dosage adjustment
b. Increased oral dose
,c. Decreased oral dose
d. Parenteral administration
Correct Answer: D
Rationale: A high first-pass effect significantly reduces bioavailability, often necessitating
parenteral routes to ensure adequate serum concentrations.
DIF: Application
REF: p. 25
TOP: Pharmacokinetics
MSC: NCLEX Category: Physiologic Integrity; Pharmacological and Parenteral Therapies
Chapter 3: Autonomic Nervous System Medications
MULTIPLE CHOICE
3. A patient on a nonselective β-blocker reports shortness of breath. The APRN should suspect:
a. Bronchoconstriction
b. Bradycardia
c. Hypotension
d. Hyperglycemia
Correct Answer: A
Rationale: Nonselective β-blockers block β2 receptors in the lungs, leading to
bronchoconstriction; bradycardia and hypotension may occur but do not explain dyspnea;
hyperglycemia is unrelated.
DIF: Application
REF: p. 72
, TOP: Pharmacodynamics
MSC: NCLEX Category: Physiologic Integrity; Pharmacological and Parenteral Therapies
Chapter 4: Anti-Infective Agents
MULTIPLE CHOICE
4. Which antibiotic requires therapeutic drug monitoring due to nephrotoxicity and
ototoxicity risk?
a. Azithromycin
b. Vancomycin
c. Amoxicillin
d. Ciprofloxacin
Correct Answer: B
Rationale: Vancomycin requires periodic serum level checks to avoid toxicity; other options
rarely necessitate monitoring.
DIF: Analysis
REF: p. 134
TOP: Nursing Process: Implementation
MSC: NCLEX Category: Physiologic Integrity; Pharmacological and Parenteral Therapies
Chapter 5: Cardiovascular Drugs
MULTIPLE CHOICE
