PHARMACOLOGICAL BASIS OF THERAPEUTICS EXAM LATEST
UPDATES -2025/2026- ACTUAL QUESTIONS WITH VERIFIED
ANSWERS ALREADY GRADED A+ GUARANTEED SUCCESS
FDA
Food and Drug Administration
2PAM
Pralidoxime
BChE
Butyrylcholinesterase
ChE
Cholinesterase
CNS
Central nervous system
CYP
Cytochrome P450
DFP
Diisopropyl fluorophosphate (diisopropyl phosphorofluoridate)
EPA
Environmental Protection Agency
PON1
, Paraoxonase isoform 1
TOCP
Triorthocresyl phosphate
Acetylcholinesterase
Enzyme that terminates the action of acetylcholine at nerve endings, inhibiting
both AChE and BChE
Physostigmine
Alkaloid obtained from the Calabar bean, historically used as an ordeal poison
Neostigmine
Compound introduced for its stimulant action on the GI tract and treatment of
myasthenia gravis
Parathion
Phosphorothioate compound widely used as an insecticide
Malathion
Insecticide containing the thionophosphorus bond found in parathion
Sarin, soman, tabun
Compounds of much greater toxicity than parathion, used as chemical warfare
agents
Acetylcholinesterase Structure
Exists in homomeric and heteromeric forms, with different molecular associations
and locations
Molecular Cloning of AChEs
A single gene encodes vertebrate AChEs, with multiple gene products differing in
carboxyl termini
Butyrylcholinesterase
UPDATES -2025/2026- ACTUAL QUESTIONS WITH VERIFIED
ANSWERS ALREADY GRADED A+ GUARANTEED SUCCESS
FDA
Food and Drug Administration
2PAM
Pralidoxime
BChE
Butyrylcholinesterase
ChE
Cholinesterase
CNS
Central nervous system
CYP
Cytochrome P450
DFP
Diisopropyl fluorophosphate (diisopropyl phosphorofluoridate)
EPA
Environmental Protection Agency
PON1
, Paraoxonase isoform 1
TOCP
Triorthocresyl phosphate
Acetylcholinesterase
Enzyme that terminates the action of acetylcholine at nerve endings, inhibiting
both AChE and BChE
Physostigmine
Alkaloid obtained from the Calabar bean, historically used as an ordeal poison
Neostigmine
Compound introduced for its stimulant action on the GI tract and treatment of
myasthenia gravis
Parathion
Phosphorothioate compound widely used as an insecticide
Malathion
Insecticide containing the thionophosphorus bond found in parathion
Sarin, soman, tabun
Compounds of much greater toxicity than parathion, used as chemical warfare
agents
Acetylcholinesterase Structure
Exists in homomeric and heteromeric forms, with different molecular associations
and locations
Molecular Cloning of AChEs
A single gene encodes vertebrate AChEs, with multiple gene products differing in
carboxyl termini
Butyrylcholinesterase
