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Exam 4 (RUSH NSG 531 Advanced Pharm) Save

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G1 Phase cellular content (not DNA) is duplicated

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Advanced Pharmacology - NSG 531 2025
Ginseng <correct answer>taken for:
Nervousness, Agitation, Insomnia, Diarrhea, Headaches, Heart Palpitation


Do not take with MAO inhibitors. Can alter affects with heart medications.
Can increase the risk of bleeding when taken with blood clotting drugs
CI: Neuro, Heart, MAO, bleeding, coag drugs


Ma Huang (Ephedra) <correct answer>Dangerously elevate blood
pressure, stimulate heart rate, and CNS
Associated with stroke, MI, and death
Banned > 10 mg in U.S. with exception of traditional Asian medicine
Metabolife
Used for weight loss, allergies, asthma, bronchitis, fever, headache


arginine <correct answer>Arginine is used for treatment of heart and blood
vessel conditions including congestive heart failure (CHF), chest pain, high
blood pressure, and coronary artery disease.


Don't use if:
excess body acid
high levels of potassium in the blood
sickle cell anemia
heart attack within the last 30 days
renal tubular acidosis
decreased kidney function

, Don't use with nitro


pt. education for herbs and nutrients <correct answer>1. herbs and
nutrients have bioactive properties and have the same safety issues as
drugs
2. always consult a reliable source before adding
3. consider when researching what are the credentials of the author of the
website, what evidence is there to support their claims, are there any
financial interests to influence the claims of the auther


biological basis of drug/herb/nutrient interactions <correct
answer>absorption (changing pH or motility of the GI tract)


Distribution (displacing agents that are bound to plasma proteins


Biotransformation (inducing or inhibiting CYP450 enzymes)


receptor binding (competitive and noncompetitive antagonism


Gompertzian Kinetics <correct answer>Cancer cells lack of normal
regulating factors leading to abnormal growth


You can go from 0 to 10^9 before symptoms
This bounces because you go on and off of chemo
That's why we do multiple rounds - so you initiate the next round of chemo
before you get back to where we started

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