Test Bank for Psychopharmacology: Drugs, the Brain and Behavior 3rd Edition by Jerrold S. Meyer & Linda F. Quenzer|9781605355559| All Chapters 1-20| LATEST

TEST BANK
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PSYCHOPHARMACOLOGY DRUGS
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THE BRAIN AND BEHAVIOR 3rd
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EDITION
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, Chapter 1: Principles of Pharmacology
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Multiple iChoice

1. refer(s) ito ispecific imolecular ichanges ithat ioccur iwhen ia idrug ibinds ito ia
iparticular itarget isite ior ireceptor, iwhile are ithe iresulting iwidespread ialterations
iin ifunction.

a. Drug iaction; itherapeutic ieffects
b. Side ieffects; idrug ieffects
c. Therapeutic ieffects; iside ieffects
d. Drug iaction; idrug ieffects
Answer: id
Textbook iReference: iPharmacology: iThe iScience iof iDrug iAction

2. After idrug iadministration ihas ioccurred, ithe iamount iof idrug iin ithe iblood ithat iis ifree
ito ibind iat ispecific itarget isites iis ireferred ito ias

a. the itherapeutic idose.
b. first-pass ieffects.
c. bioavailability.
d. ED50.
Answer: ic
Textbook iReference: iPharmacokinetic iFactors iDetermining iDrug iAction

3. The ispecific imolecular ichanges ithat ioccur iwhen ia idrug ibinds ito ia iparticular itarget
isite ior ireceptor iare ireferred ito ias

a. drug ieffects.
b. drug iaction.
c. side ieffects.
d. placebo ieffects.
Answer: ib
Textbook iReference: iPharmacology: iThe iScience iof iDrug iAction

4. Which iof ithe ifollowing iis inot ia ipossible iexplanation ifor iplacebo ieffects?
a. Pavlovian iconditioning
b. Genetic ivariation
c. Drug icompetition
d. Expectation iof ioutcome
Answer: ic
Textbook iReference: iPharmacology: iThe iScience iof iDrug iAction




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,5. The administration iof ioxytocin ihas ibeen iproposed ias ia itreatment ifor iautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: ic
Textbook iReference: iPharmacokinetic iFactors iDetermining iDrug iAction

6. Which ifactor idoes inot iaffect ithe ipharmacokinetics iof ia idrug?
a. Route iof iadministration
b. Lipid isolubility
c. Depot ibinding
d. Drug iaction
Answer: id
Textbook iReference: iPharmacokinetic iFactors iDetermining iDrug iAction

7. First-pass imetabolism ioccurs iwhen idrugs iare itaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: ia
Textbook iReference: iPharmacokinetic iFactors iDetermining iDrug iAction

8. The iarea ipostrema iis ione iarea iin ithe ibrain iwhere ithe is inot icomplete.
a. cerebrospinal ifluid
b. blood–brain ibarrier
c. choroid iplexus
d. phospholipid imembrane
Answer: ib
Textbook iReference: iPharmacokinetic iFactors iDetermining iDrug iAction

9. First-pass imetabolism ioccurs iwith iorally iadministered idrugs ibecause
a. their iabsorption iis islowed iby ifood.
b. drugs iabsorbed iinto ithe ibloodstream ifrom ithe istomach igo ito ithe iliver ion ithe iway
ito igeneral icirculation.

c. drugs imust ifirst isurvive ithe iacidic ienvironment iof ithe istomach.
d. salivary ienzymes iin ithe imouth ibegin ithe iprocess iof imetabolism.
Answer: ib
Textbook iReference: iPharmacokinetic iFactors iDetermining iDrug iAction

10. Toxic isubstances iin ithe iblood itrigger ia ivomiting iresponse iby iactivating ithe
a. blood–brain ibarrier.
b. choroid iplexus.
c. area ipostrema.
d. median ieminence.




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, Answer: ic
Textbook iReference: iPharmacokinetic iFactors iDetermining iDrug iAction

11. Drugs iadministered i_ have ithe imost irapid ionset iof iaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: id
Textbook iReference: iPharmacokinetic iFactors iDetermining iDrug iAction

12. Ionization iof ia idrug idepends ion ithe of ithe isolution iand ithe ofithe
idrug.

a. pH; ipKa
b. pKa; ipH
c. concentration; ilipid isolubility
d. pH; iconcentration
Answer: ia
Textbook iReference: iPharmacokinetic iFactors iDetermining iDrug iAction

13. The iabsorption iof ia idrug idepends ion iall iof ithe ifollowing iexcept
a. lipid isolubility.
b. ionization.
c. body itemperature.
d. the iconcentration iof ithe idrug.
Answer: ic
Textbook iReference: iPharmacokinetic iFactors iDetermining iDrug iAction

14. Drugs ithat iare should ibe iavoided iby iwomen iof ichildbearing iage.
a. teratogenic
b. able ito icross ithe iplacental ibarrier
c. psychoactive
d. highly ilipid-soluble
Answer: ia
Textbook iReference: iPharmacokinetic iFactors iDetermining iDrug iAction

15. Agents ithat iinduce idevelopmental iabnormalities iin ia ifetus iare iknown ias
a. psychoactive idrugs.
b. illicit idrugs.
c. teratogens.
d. placental idrugs.
Answer: ic
Textbook iReference: iPharmacokinetic iFactors iDetermining iDrug iAction

16. Depot ibinding iis isaid ito ioccur iwhen idrugs
a. bind ito itheir itarget isites.




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