EXAM 3 REVIEW 2025 QUESTIONS AND
ANSWERS
Low-dose colchine - ANS 1.2 mg at first sign of flare, followed by 0.6 mg one hour later for a
total dose of 1.8 mg. Used for gout
High-dose colchine - ANS 1.2 mg followed by 0.6 mg every 4-6 hours totaling 4.8 mg.- not
recommended/ used for gout
Gout - ANS Uric acid, liver and kidney lab, BUN, creatinine, and creatinine clearance should
be monitored in the treatment of this disease, CBC if colchicine is used
Colchine - ANS This medication treats gout, can cause severe diarrhea, nausea, vomiting,
abdominal pain
Febuxostat (Uloric) - ANS When prescribing this medication, patients should be taught that
gout may worsen before it improves. Can use NSAID or colchicine with treatment for up to 6
months. Preventative therapy
Corticosteroids adverse effects - ANS These medications can cause the following adverse
effects if taken for six months or more: Osteoporosis and poor diabetic control. Patients should
report black, tarry stools or abdominal pain...more
Corticosteroids - ANS These medications should be tapered to avoid recurrent activity of the
underlying disease and possible cortisol deficiency resulting from the hypothalamic-pituitary-
adrenal axis suppression during the period of steroid therapy.
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, Black Box Warning on NSAIDS - ANS Increased risk of serious cardiovascular thrombotic
events, such as myocardial infarction and stroke. These medications can also cause serious GI
events such as bleeding, ulceration or perforation of stomach or intestines, which can be fatal.
Pain management - ANS Non-opioid first choice- especially for inflammatory pain (NSAID).
May use Tylenol for non-inflammatory pain
Ibuprofen - ANS Non-selective COX-2 inhibitor, inhibits COX-2 which decreases prostaglandin
synthesis in mediating inflammation, pain, fever, and swelling
Acetaminophen - ANS Liver failure / renal failure
Symptoms of hypoglycemia - ANS Decreased LOC, hunger, diaphoresis, weakness, dizziness
and tachycardia
Symptoms of hyperglycemia - ANS Polyuria, polydipsia and polyphagia (weight loss)
Symptoms of DKA - ANS Kussmaul's respiration, ketone odor of the breath (fruity breath),
vomiting, dehydration, abdominal pain, and neurologic symptoms such as lethargy; can
progress to coma in later stages if left untreated.
Metformin - ANS This medication decreases hepatic glucose output inhibiting
gluconeogenesis. It also increases insulin mediated glucose utilization in peripheral tissues. This
medication decreases intestinal absorption of glucose. This medication may also be used in
diabetics to decrease cholesterol and triglyceride levels.
Metformin - ANS When patients are prescribed this medication, the primary care provider
should assess serum creatinine, renal function, and creatinine clearance initially and annually.
Gliptins (DPP4 inhibitors) - ANS These medications increase the incretin levels, which inhibit
glucagon release; this subsequently increases insulin secretion, decreases gastric emptying and
decreases blood glucose levels.
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