PHARMACOLOGY D441 QUESTIONS
WITH CORRECT ANSWERS
Medication Administration
Principles of Drug Reconstitution - CORRECT ANSWER --process of adding a liquid dilute
(SOLVENT) to a powdered med (SOLUTE) to make a solution (w med now in liquid form)
-necessary bc certain meds doesn't stay stable long enough to be distributed in a solution type
of form so its sent in as a powder to be reconstituted with a liquid before drug administration
-read directions on insert / label: will tell you the type and ain't of solvent to add (ex. Water,
sterile water, saline)
-use syringe and needle to draw solvent-> powdered med
-roll vial between hands to mix (making sure the med dissolves completely in the solution)
-single dose (discard after admin) multi dose (stored and used later, document)
Pediatric Dosing - CORRECT ANSWER -- more sensitive than adults and may need to calculate
(wt, ht, physical condition, immature systems, and metabolism)
-make sure abiding by the 6 rights of drug admin
-pediatric doses are often less than 1 mL and require a tuberculin syringe for accurate dosing
-pediatric meds are calculated using infant or child's Kg weight
CONVERTING LBS-> KG - CORRECT ANSWER -2.2 lb = 1 kg
X Kg= 1 kg/2.2 lb x 24 lb/ 1
Converting grams to kilograms - CORRECT ANSWER -1000 g = 1 KG
X kg = 1 kg/1000g x 2300 g / 1
,Calculating safe dose range pediatric with given wt - CORRECT ANSWER -Example (DA version)
1. Convert wt in lb->kg
2. Note the recommended dose range
3. Calculate the minimum dose first:
Xmg/dose=10mg/kg/dose X 1 kg/2.2lb x 22lb/1
4. Calculate maximum dose:
X mg/dose= 15mg/kg/dose X 1kg/2.2lb x 22lb/1
5. Child may receive #-# mg of med as a single dose
Obstetric Nursing - CORRECT ANSWER -came from the word "obstetric" means "midwife".
-commonly used IV meds to prevent seizures in pregnant woman (Mg Sulfatem CNS depressant)
CNS Depressants
Function - CORRECT ANSWER --promote relaxation
-relieve anxiety
-help or induce sleep
-moderate sedation (before and during invasive procedures like colonoscopies
CNS Depressant
DRUG Types/ MOA - CORRECT ANSWER --Benzodiazepines (diazePAM, midazolAM, lorazePAM,
chlordiazepoxide)
Long acting: clonazepam (Klonopin), Diazeopam (Valium), Flurazepam (Dalmane)
MOA:
,-enhances the GABA effect of the CNS which is what promotes the sedation effect
Contraindications;
Benzodiazapines can induce daytime sleeping in few cases so to reduce that possibility,
Zolpidem is prescribed (non-benzo). Zolpidem is known to cause sleep walking
Midazolam (Versed) Indications - CORRECT ANSWER --mainly used for moderate sedation
-helps for amnesia /sedation
-helps to reduce anxiety
Route: IV
Temaxepam (Restoril) - CORRECT ANSWER --intermediate acting Benzo (induces sleep within 30
mins)
-take 1 hr before bed because it has a long onset of action
Eszopiclone (Lunesta)
NON-BENZODIAZAPINE/MISC Hypnotic - CORRECT ANSWER --long term use
-provides a full 8 hrs of sleep
Ramelteon (Rozerem)
NON-BENZO/ MISC Hypnotic - CORRECT ANSWER --structurally similar to melatonin (Which
regulates circadian rhythm)
-agonist at melatonin receptors in the CNS
-used as a hypnotic
-used for pts who have trouble sleeping
, Contraindications:
-people with severe liver dysfunction
Drug Interactions:
-fluconazole
-ketaconazole
-rifampin
Zolpidem (Ambien)
NON BENZO/MISC Hypnotic - CORRECT ANSWER --short-acting non Benzo hypnotic
Adverse Effects:
-somnambulation (sleep walking)
Barbiturates MOA/ INDICATIONS - CORRECT ANSWER --Barbiturates are CNS depressants that
act on the brain stem in the area called 'reticular formation'.. they act by reducing the nerve
impulses traveling to the cerebral Cortex
-can also help to treat seizures because it inhibits the GABA neurotransmitters in the CNS
INDICATIONS:
-Sedation/ hypnotic
-*the use of these are no longer used for sleep induction*
-ultrashort acting: used for anesthesia for short surgery
-short acting:sedation, seizures
Barbiturates
Contraindications, Adverse Effects - CORRECT ANSWER -Contraindications:
WITH CORRECT ANSWERS
Medication Administration
Principles of Drug Reconstitution - CORRECT ANSWER --process of adding a liquid dilute
(SOLVENT) to a powdered med (SOLUTE) to make a solution (w med now in liquid form)
-necessary bc certain meds doesn't stay stable long enough to be distributed in a solution type
of form so its sent in as a powder to be reconstituted with a liquid before drug administration
-read directions on insert / label: will tell you the type and ain't of solvent to add (ex. Water,
sterile water, saline)
-use syringe and needle to draw solvent-> powdered med
-roll vial between hands to mix (making sure the med dissolves completely in the solution)
-single dose (discard after admin) multi dose (stored and used later, document)
Pediatric Dosing - CORRECT ANSWER -- more sensitive than adults and may need to calculate
(wt, ht, physical condition, immature systems, and metabolism)
-make sure abiding by the 6 rights of drug admin
-pediatric doses are often less than 1 mL and require a tuberculin syringe for accurate dosing
-pediatric meds are calculated using infant or child's Kg weight
CONVERTING LBS-> KG - CORRECT ANSWER -2.2 lb = 1 kg
X Kg= 1 kg/2.2 lb x 24 lb/ 1
Converting grams to kilograms - CORRECT ANSWER -1000 g = 1 KG
X kg = 1 kg/1000g x 2300 g / 1
,Calculating safe dose range pediatric with given wt - CORRECT ANSWER -Example (DA version)
1. Convert wt in lb->kg
2. Note the recommended dose range
3. Calculate the minimum dose first:
Xmg/dose=10mg/kg/dose X 1 kg/2.2lb x 22lb/1
4. Calculate maximum dose:
X mg/dose= 15mg/kg/dose X 1kg/2.2lb x 22lb/1
5. Child may receive #-# mg of med as a single dose
Obstetric Nursing - CORRECT ANSWER -came from the word "obstetric" means "midwife".
-commonly used IV meds to prevent seizures in pregnant woman (Mg Sulfatem CNS depressant)
CNS Depressants
Function - CORRECT ANSWER --promote relaxation
-relieve anxiety
-help or induce sleep
-moderate sedation (before and during invasive procedures like colonoscopies
CNS Depressant
DRUG Types/ MOA - CORRECT ANSWER --Benzodiazepines (diazePAM, midazolAM, lorazePAM,
chlordiazepoxide)
Long acting: clonazepam (Klonopin), Diazeopam (Valium), Flurazepam (Dalmane)
MOA:
,-enhances the GABA effect of the CNS which is what promotes the sedation effect
Contraindications;
Benzodiazapines can induce daytime sleeping in few cases so to reduce that possibility,
Zolpidem is prescribed (non-benzo). Zolpidem is known to cause sleep walking
Midazolam (Versed) Indications - CORRECT ANSWER --mainly used for moderate sedation
-helps for amnesia /sedation
-helps to reduce anxiety
Route: IV
Temaxepam (Restoril) - CORRECT ANSWER --intermediate acting Benzo (induces sleep within 30
mins)
-take 1 hr before bed because it has a long onset of action
Eszopiclone (Lunesta)
NON-BENZODIAZAPINE/MISC Hypnotic - CORRECT ANSWER --long term use
-provides a full 8 hrs of sleep
Ramelteon (Rozerem)
NON-BENZO/ MISC Hypnotic - CORRECT ANSWER --structurally similar to melatonin (Which
regulates circadian rhythm)
-agonist at melatonin receptors in the CNS
-used as a hypnotic
-used for pts who have trouble sleeping
, Contraindications:
-people with severe liver dysfunction
Drug Interactions:
-fluconazole
-ketaconazole
-rifampin
Zolpidem (Ambien)
NON BENZO/MISC Hypnotic - CORRECT ANSWER --short-acting non Benzo hypnotic
Adverse Effects:
-somnambulation (sleep walking)
Barbiturates MOA/ INDICATIONS - CORRECT ANSWER --Barbiturates are CNS depressants that
act on the brain stem in the area called 'reticular formation'.. they act by reducing the nerve
impulses traveling to the cerebral Cortex
-can also help to treat seizures because it inhibits the GABA neurotransmitters in the CNS
INDICATIONS:
-Sedation/ hypnotic
-*the use of these are no longer used for sleep induction*
-ultrashort acting: used for anesthesia for short surgery
-short acting:sedation, seizures
Barbiturates
Contraindications, Adverse Effects - CORRECT ANSWER -Contraindications:
