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WGU D027 OBJECTIVE ASSESSMENT ACTUAL EXAM 2025/2026 ACCURATE QUESTIONS AND CORRECT DETAILED ANSWERS WITH RATIONALES || 100% GUARANTEED PASS BRAND NEW VERSION

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WGU D027 OBJECTIVE ASSESSMENT ACTUAL EXAM 2025/2026 ACCURATE QUESTIONS AND CORRECT DETAILED ANSWERS WITH RATIONALES || 100% GUARANTEED PASS BRAND NEW VERSION 1. What organ does cystic fibrosis affect? - ANSWER Affects the pancreas causing secretions into the lungs 2. What is Klinefelter syndrome? - ANSWER An extra X chromosome for males so example XXY causing female-like qualities 3. What is Turner Syndrome? - ANSWER females. missing or deformed x chromosome. right hemisphere dysfunction, hearing loss, ear infection, language and articulation disorders, visual spatial and attentional problems 4. What is beta thalassemia? - ANSWER a condition in which the synthesis of the beta-globin chains is decreased or absent. Causes low hemoglobin. 5. Which medication is contraindicated in a patient with Beta Thalassemia? - ANSWER Ferrous Sulfate 6. What causes vasodilation, bronchoconstriction, and helps with memory and sleep? - ANSWER histamine- 1 7. What are side effects of antihistamines? - ANSWER sedation (only H-1), dry mucus membranes, urinary hesitancy, and constipation. 8. Which medication is given after an MI? - ANSWER Beta blocker is given for 6 months to prevent another MI 9. When should medication reconciliation be done? - ANSWER Within 30 days of discharge 10. Which drug class is used as the first line of treatment for depression? - ANSWER SSRIs because of the low side effects and effectiveness. 11. What is the first line of treatment for uncomplicated otitis media in pediatric patient without comorbidities? - ANSWER Amoxicillin 12. How do you test for postural orthostatic tachycardia syndrome? - ANSWER Tilt test 13. What is Florinef (corticosteroid) used for? - ANSWER Used to treat postural hypotension and adrenal insufficiency. 14. What are the side effects of Florinef? - ANSWER Nausea, headache, sleep problems, and mood changes. 15. What is the off label use for prazosin/minipress (alpha- 1 blocker)? - ANSWER Sleep aid for patients diagnosed with PTSD 16. Which medications are used to treat myasthenia gravis? - ANSWER Corticosteroids and cholinesterase inhibitors. 17. Side effects of cholinesterase inhibitors (neostigmine): - ANSWER Excessive salvation, urinary urgency, sweating, spasm, bradycardia 18. What is the first line of treatment for uncomplicated hypertension? - ANSWER Hydrochlorothiazide(thiazide diuretic) orally with lifestyle changes. 19. What might cause ataxia in a pediatric patient? - ANSWER - Fragile X syndrome - Prader Willie Syndrome by deletion of chromosome 15 from father 20. Combined ___________ are contraindicated when breast feeding. - ANSWER Oral contraceptives 21. Which antibiotic would you use for treatment of UTI during pregnancy? - ANSWER One-time dose of Fosfomycin and cephalexin. NO PENCILLINS 22. How to treat pediatric UTI with no comorbidities? - ANSWER Trimethoprim/sulfamethoxazole (Bactrim, Septra) Augmentin Cephalosporins 23. Which parent does color blindness come from? - ANSWER X-linked so mother. 50% chance of getting it. Gene OPN1MW on chromosome 23 is mutated causing color blindness. 24. What is the first treatment for sickle cell crisis? - ANSWER Hydration 25. Parental care of the newborn with sickle cell anemia: - ANSWER - Infant will be anemic - Increased risk for infection - May have spleen or liver damage causing jaundice - May have crying episodes from pain and swelling of extremities - Hydrate, administer vaccines, antibiotics when necessary, folic acid administration, and regular eye exams 26. Should you admit or monitor a young athletic patient with bradycardia? - ANSWER Monitor as it is normal. 27. Which part of the GI tract does Crohn's disease effect? - ANSWER Affects all GI tract and has skip lesions 28. Which patients have an increased risk of inflammatory bowel disease? - ANSWER Patients with atopic dermatitis and eczema 29. What diagnostic labs will be drawn for ulcerative colitis? - ANSWER CBC, CRP, ESR, LFT, electrolyte panel, and ANA 30. A Japanese male present with hypertension and chronic kidney disease, which antihypertensive would you give? - ANSWER ACE inhibitor or ARB. Next course of action is to reduce amount of salt in diet. 31. Which medications are given PRN for anxiety? - ANSWER Benzodiazepines (Diazepam), Vistaril (antihistamine), Seroquel (antipsychotic effects), SSRIs (Prozac, Paxil, Zoloft), and Wellbutrin (antidepressant), and Risperidone (side effect is neutropenia) 32. Which medication can be given to treat schizophrenia? - ANSWER Chlorpromazine (antipsychotic) 33. Which medications could be alternatives to treat neuropathic pain? - ANSWER Cymbalta (Duloxetine) and Lyrica (pregabalin) 34. What should be avoided if a patient has a G6PD deficiency? - ANSWER Mothballs (naphthalene), fava beans, red wine, all beans, blueberries, soya products, tonic water, and camphor. 35. G6PD deficiency - ANSWER - Low NADPH leads to hemolytic anemia (free radicals) - X-linked recessive 36. What should you do for a mild reaction to IgM? - ANSWER If fast, slow the infusion. Administer acetaminophen, diphenhydramine, and steroids. 37. What is the most common type of lung cancer? - ANSWER Small cell lung carcinomas (SCLCs) 38. How do you diagnose lung cancer? - ANSWER - Chest X-ray - Test for mutation in epidermal growth factor receptor (EFGR) 39. Name an adrenocortical steroid indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome - ANSWER Florinef 40. What medications should you avoid if taking Ginkgo Biloba or garlic - ANSWER Anticoagulants or antiplatelets - increases risk of bleeding 41. What time of contraceptive should be avoided when breastfeeding? - ANSWER combined contraceptives 42. What is cinnamon used for? - ANSWER Diabetes 43. First line treatment for uncomplicated otitis media in pediatric patient without comorbidities? - ANSWER amoxicillin 44. What is the treatment for addisons disease or for the treatment of salt losing adrenogenital syndrome? - ANSWER Florinef 45. Side Effects of florinef? - ANSWER GI, Headache, menstrual changes, skin changes(appearance, color, thinning, easy bruising/bleeding), dizziness, bone/muscle pain, eye problems or mood changes 46. Off label use for BPH or sleep aid for PTSD? - ANSWER Prazosin/Minipress 47. What med to give diabetic patient for hypertension? - ANSWER ACE Inhibitor the "prils" 48. Common Side Effect of ACE Inhibitor - ANSWER dry cough, inc K level, fatigue, headaches, loss of taste 49. What should be avoided when on ACE Inhibitors? - ANSWER NSAIDS 50. 1st line treatment asthma - ANSWER SABA PRN 51. step 2 of asthma - ANSWER start low dose ICS (when interupting sleep at night) 52. 3rd step asthma - ANSWER low dose ICS + LABA or medium dose ICS 53. 4th step asthma - ANSWER medium dose ICS + LABA 54. 5th step asthma - ANSWER high dose ICS + LABA 55. Step 6 asthma - ANSWER high dose ICS + LABA + oral corticosteroid 56. occurs when the body's immune system produces antibodies that block the chemical needed for muscles to contract - ANSWER Myasthenia Gravis 57. Myasthenia Gravis treatment - ANSWER cholinesterase inhibtors and autoimmune treatments like coritcosteroids 58. side effects of cholinesterase inhibitors - ANSWER NVD, muscle cramps, weigh loss, headaches, insomnia, abnormal dreams rare but dangerous worsening of the thyrotoxic state, in which death can occur within 48 hours without treatment. The condition may develop spontaneously, but it usually occurs in individuals who have undiagnosed or partially treated severe hyperthyroidism and who are subjected to excessive stress from other causes. These causes may include infection, pulmonary or cardiovascular disorders, trauma, burns, seizures, surgery (especially thyroid surgery), obstetric complications, emotional distress, or dialysis - ANSWER Thyrotoxicosis/Thyrotoxic crisis (thyroid storm) 59. Symptoms of thyroid storm are caused by? - ANSWER The symptoms of thyroid crisis are caused by the sudden release and increased action of thyroxine (T4) and triiodothyronine (T3) exceeding metabolic demands. 60. hypothyroidism - ANSWER High TSH, low T3 61. Which one of the following meds is used to prevent recurrence of chronic migraines? -Propranolol -Dihydroergotamine -Naproxen -Sumitriptan - ANSWER Propranolol 62. Which of the following is not a function involving the kidneys? -Regulation of anti-diuretic hormone -Release of erythropoietin -Release of renin -Release of oxytocin - ANSWER Release of oxytocin 63. Which vaccine should be avoided in a 30-week pregnant female? -Tdap -Influenza -Hepatitis B -Varicella - ANSWER Varicella 64. Which HTN meds should the RN avoid when treating a pt with emphysema? -Calcium channel blocker -ACE inhibitor -Beta blockers -Diuretics - ANSWER Beta blockers 65. Short-acting Beta 2 agonists reduce symptoms of asthma by causing; -Decrease airway sensitivity -Bronchiole smooth muscle relaxation -Bronchiole smooth muscle constriction -Decrease immune hypersensitivity - ANSWER Bronchiole smooth muscle relaxation 66. Which vitamin may be used as a concomitant tx in managing a pt with schizophrenia? B1 C D E - ANSWER B1 67. Which endocrine hormone is responsible for the regulation of calcium? Epinephrine Parathyroid hormone Thyroid hormone Insulin - ANSWER Parathyroid hormone 68. The MOA of radioactive iodine in the treatment of Graves' disease is to: Destroy the overactive thyroid tissue Alter thyroid metabolic rate Reduce the production of TSH 69. Relieve distress caused by increased thyroid size - ANSWER Destroy the overactive thyroid tissue 70. Drugs used to manage a pt with peripheral artery disease and type 1 DM may include all of the following except: Daily aspirin use Lipid lowering with an HMG-CoA reductase inhibitor (statin) Gabapentin Insulin - ANSWER Gabapentin 71. What is the intended therapeutic action of ICS when used to treat COPD? A reversal of fixed airway obstruction Reduction of airway inflammation Improvement of central respiratory drive Mucolytic activity - ANSWER Reduction of airway inflammation 72. Which of the following medications is an adrenergic antagonist? Atenolol Metoprolol Propranolol Dopamine - ANSWER Dopamine 73. Unstable Angina - ANSWER frequent, severe and prolonged chest pressure or pain. Triggers not predictable, sx with activity or during rest. 74. A female who is a carrier of a sex-linked trait will have a ____chance of passing the trait to her male offspring. 25% 50% 75% 100% - ANSWER 50% 75. Which lab helps dx Celiac disease, and which pathology often coexists with Celiacs disease? ALT; POTS AST; pancreatitis TTG; migraines CBC; renal failure - ANSWER TTG; migraines Rationale: Tissue transport glutaminase-antibody formed by body. 76. Hypothalamic hamartoma - ANSWER may be caused by GL13 mutation Rare, benign gelastic seizures, precocious puberty, problems w/ mood/cognition/behavior 77. Step 2 of the stepwise approach for asthma mgmt adds which of the following meds? Low dose inhaled corticosteroid High dose inhaled corticosteroid Long-acting beta agonist Leukotriene receptor antagonist - ANSWER Low dose inhaled corticosteroid Rationale: 1-PRN albuterol inhaler. 2-low-dose inhaled corticosteroid 78. Crohn's disease - ANSWER -a chronic autoimmune disorder that can occur anywhere in the digestive tract; however, it is most often found in the ileum and in the colon -Skip lesions -Cobble-stoning -antibody test: ASCA protein -Low residue diet, avoid caffeine, ETOH, diuretics, large grains 79. Ulcerative Colitis - ANSWER -a chronic condition of unknown cause in which repeated episodes of inflammation in the rectum and large intestine cause ulcers and irritation -pANCA antibody -limit dairy, small meals 80. Which antibiotic is contraindicated in the tx of UTI during pregnancy? Fosfomycin Ciprofloxacin Penicillin Nitrofurantoin - ANSWER Ciprofloxacin Rationale: it affects muscular skeletal connective tissues, especially tendons. In pregnancy, you can actually cause those muscular skeletal connective tissues to form incorrectly, causing the fetus to be greatly impacted. Use with caution or not at all in kids-especially those growing or in sports, It can cause tendon rupture. Fluoroquinolones: Cipro, levofloxacin, ofloxacin 81. myasthenia gravis - ANSWER a chronic autoimmune disease that affects the neuromuscular junction and produces serious weakness of voluntary muscles (eyelids, arms, legs) 82. Hashimoto's disease - ANSWER -an autoimmune disease in which the body's own antibodies attack and destroy the cells of the thyroid gland -hypothyroid slows everything down -anti-TPO, anti-Tg, TBII 83. cor pulmonale, right ventricular failure - ANSWER enlargement of the right ventricle, resulting from chronic disease within the lungs (pulmonary HTN), that causes congestion within the pulmonary circulation and resistance of blood flow to the lungs 84. Left sided heart failure - ANSWER prolonged HTN, MI, valvular disorder then causing pulmonary issues-Pulmonary edema Sx: SOB, Crackles, Oliguria, Frothy Sputum, Displaced Apical Pulse (Hypertrophy) Tx: Diuretics, ACE inhib, BBlocker, Dig 85. Ejection Fraction (EF) - ANSWER = 55% is normal 50-54% is preserved 50% is reduced 86. _____ should be assessed before alpha1/beta 1 & 2 antagonist administration, & off-label indications may include _____. Heart rate; treatment of insomnia & or anxiety Urinary output; tx for fluid overload Blood glucose level; tx for overeating RR; treatment for asthma - ANSWER Heart rate; treatment of insomnia & or anxiety Rationale: alpha blockers can be used for treatment of insomnia, especially insomnia related to PTSD

Meer zien Lees minder
Instelling
WGU D027 Advanced Pathopharmacological Foundation
Vak
WGU D027 Advanced Pathopharmacological Foundation

Voorbeeld van de inhoud

WGU D027 OBJECTIVE ASSESSMENT ACTUAL
EXAM 2025/2026 ACCURATE QUESTIONS AND
CORRECT DETAILED ANSWERS WITH
RATIONALES || 100% GUARANTEED PASS
<BRAND NEW VERSION>




1. What organ does cystic fibrosis affect? - ANSWER ✔ Affects the pancreas
causing secretions into the lungs

2. What is Klinefelter syndrome? - ANSWER ✔ An extra X chromosome for
males so example XXY causing female-like qualities

3. What is Turner Syndrome? - ANSWER ✔ females. missing or deformed x
chromosome. right hemisphere dysfunction, hearing loss, ear infection,
language and articulation disorders, visual spatial and attentional problems

4. What is beta thalassemia? - ANSWER ✔ a condition in which the synthesis
of the beta-globin chains is decreased or absent. Causes low hemoglobin.

5. Which medication is contraindicated in a patient with Beta Thalassemia? -
ANSWER ✔ Ferrous Sulfate

6. What causes vasodilation, bronchoconstriction, and helps with memory and
sleep? - ANSWER ✔ histamine- 1

7. What are side effects of antihistamines? - ANSWER ✔ sedation (only H-1),
dry mucus membranes, urinary hesitancy, and constipation.

8. Which medication is given after an MI? - ANSWER ✔ Beta blocker is given
for 6 months to prevent another MI

,9. When should medication reconciliation be done? - ANSWER ✔ Within 30
days of discharge

10.Which drug class is used as the first line of treatment for depression? -
ANSWER ✔ SSRIs because of the low side effects and effectiveness.

11.What is the first line of treatment for uncomplicated otitis media in pediatric
patient without comorbidities? - ANSWER ✔ Amoxicillin

12.How do you test for postural orthostatic tachycardia syndrome? - ANSWER
✔ Tilt test

13.What is Florinef (corticosteroid) used for? - ANSWER ✔ Used to treat
postural hypotension and adrenal insufficiency.

14.What are the side effects of Florinef? - ANSWER ✔ Nausea, headache,
sleep problems, and mood changes.

15.What is the off label use for prazosin/minipress (alpha- 1 blocker)? -
ANSWER ✔ Sleep aid for patients diagnosed with PTSD

16.Which medications are used to treat myasthenia gravis? - ANSWER ✔
Corticosteroids and cholinesterase inhibitors.

17.Side effects of cholinesterase inhibitors (neostigmine): - ANSWER ✔
Excessive salvation, urinary urgency, sweating, spasm, bradycardia

18.What is the first line of treatment for uncomplicated hypertension? -
ANSWER ✔ Hydrochlorothiazide(thiazide diuretic) orally with lifestyle
changes.

19.What might cause ataxia in a pediatric patient? - ANSWER ✔ - Fragile X
syndrome
- Prader Willie Syndrome by deletion of chromosome 15 from father

20.Combined ___________ are contraindicated when breast feeding. -
ANSWER ✔ Oral contraceptives

,21.Which antibiotic would you use for treatment of UTI during pregnancy? -
ANSWER ✔ One-time dose of Fosfomycin and cephalexin.
NO PENCILLINS

22.How to treat pediatric UTI with no comorbidities? - ANSWER ✔
Trimethoprim/sulfamethoxazole (Bactrim, Septra)
Augmentin
Cephalosporins

23.Which parent does color blindness come from? - ANSWER ✔ X-linked so
mother. 50% chance of getting it. Gene OPN1MW on chromosome 23 is
mutated causing color blindness.

24.What is the first treatment for sickle cell crisis? - ANSWER ✔ Hydration

25.Parental care of the newborn with sickle cell anemia: - ANSWER ✔ - Infant
will be anemic
- Increased risk for infection
- May have spleen or liver damage causing jaundice
- May have crying episodes from pain and swelling of extremities
- Hydrate, administer vaccines, antibiotics when necessary, folic acid
administration, and regular eye exams

26.Should you admit or monitor a young athletic patient with bradycardia? -
ANSWER ✔ Monitor as it is normal.

27.Which part of the GI tract does Crohn's disease effect? - ANSWER ✔
Affects all GI tract and has skip lesions

28.Which patients have an increased risk of inflammatory bowel disease? -
ANSWER ✔ Patients with atopic dermatitis and eczema

29.What diagnostic labs will be drawn for ulcerative colitis? - ANSWER ✔
CBC, CRP, ESR, LFT, electrolyte panel, and ANA

30.A Japanese male present with hypertension and chronic kidney disease,
which antihypertensive would you give? - ANSWER ✔ ACE inhibitor or
ARB. Next course of action is to reduce amount of salt in diet.

, 31.Which medications are given PRN for anxiety? - ANSWER ✔
Benzodiazepines (Diazepam), Vistaril (antihistamine), Seroquel
(antipsychotic effects), SSRIs (Prozac, Paxil, Zoloft), and Wellbutrin
(antidepressant), and Risperidone (side effect is neutropenia)

32.Which medication can be given to treat schizophrenia? - ANSWER ✔
Chlorpromazine (antipsychotic)

33.Which medications could be alternatives to treat neuropathic pain? -
ANSWER ✔ Cymbalta (Duloxetine) and Lyrica (pregabalin)

34.What should be avoided if a patient has a G6PD deficiency? - ANSWER ✔
Mothballs (naphthalene), fava beans, red wine, all beans, blueberries, soya
products, tonic water, and camphor.

35.G6PD deficiency - ANSWER ✔ - Low NADPH leads to hemolytic anemia
(free radicals)
- X-linked recessive

36.What should you do for a mild reaction to IgM? - ANSWER ✔ If fast, slow
the infusion. Administer acetaminophen, diphenhydramine, and steroids.

37.What is the most common type of lung cancer? - ANSWER ✔ Small cell
lung carcinomas (SCLCs)

38.How do you diagnose lung cancer? - ANSWER ✔ - Chest X-ray
- Test for mutation in epidermal growth factor receptor (EFGR)

39.Name an adrenocortical steroid indicated as partial replacement therapy for
primary and secondary adrenocortical insufficiency in Addison's disease and
for the treatment of salt-losing adrenogenital syndrome - ANSWER ✔
Florinef

40.What medications should you avoid if taking Ginkgo Biloba or garlic -
ANSWER ✔ Anticoagulants or antiplatelets - increases risk of bleeding

Geschreven voor

Instelling
WGU D027 Advanced Pathopharmacological Foundation
Vak
WGU D027 Advanced Pathopharmacological Foundation

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Aantal pagina's
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Geschreven in
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