NU 545 Advance Pathophysiology Comprehensive
Predictor Verified Multiple Choice and Conceptual
Actual Exam Questions With Reviewed 100%
Correct Detailed Answers
Guaranteed Pass!!Current Update
1. What is Nociceptive transmission? What type of nerves are involved? -
ANSWER Mechanical, Thermal, and chemical causes of damage to the
body. carried from the periphery to the CNS. Large myelinated A-delta fibers
and small unmyelinated C fibers terminate in the substantia gelatinosa.
2. What is non-nociceptive stimulation? What type of nerves are involved? -
ANSWER touch sensors in the skin; rubbing a painful area. low intensity
stimuli. closure of partial close of the spinal gates = decreased pain
perception.
Large A-beta fibers
3. What are Nociceptors? - ANSWER free nerve endings in the afferent
PNS that selectively respond to different chemical, mechanical, and thermal
stimuli. When stimulated they cause nociceptive pain.
4. What are the 4 phases of Nociception? - ANSWER 1. Transduction
2. Transmission
3. Perception
4. Modulation
,5. What are A-delta fibers? - ANSWER lightly myelinated medium-sized
fibers that are stimulated by severe mechanical deformation and/or
extremes of temperature.
• cause reflex withdrawal of affected body part BEFORE pain sensation
is perceived
*sharp, well-localized "fast" pain sensations
6. Unmyelinated C Fibers - ANSWER Smaller unmyelinated polymodal
fibers
*Stimulated by mechanical, thermal, and chemical nociceptors
*Slowly transmit dull, aching, or burning sensations that are poorly localized
and longer lasting
7. A Beta fibers - ANSWER Large myelinated fibers
*transmit touch and vibration sensations
*Do NOT normally transmit pain, but play a role in pain modulation
8. What are the two types of fibers that transmit the nerve action potentials
generated by excitation of any of the nociceptors? - ANSWER A-delta
and C fibers
*first order sensory afferents coming into the gate at the dorsal horn of the
spinal cord.
, 9. Explain Pain transmission - ANSWER conduction of pain impulses along
the A-delta and C fibers into the dorsal horn of the spinal cord and
brainstem, thalamus, and cortex
10.Where in the CNS does pain perception occur? - ANSWER Reticular and
limbic systems and the cerebral cortex. Conscious awareness of pain.
11.Describe the Sensory-discriminative system - ANSWER Mediated by the
somatosensory cortex
*responsible for identifying the presence, character, location, and intensity of
pain
12.Describe the Affective-motivational system - ANSWER mediated
through the reticular formation, limbic system, and brainstem with
projections to the prefrontal cortex
13.*determines an individual's condition avoidance behaviors and emotional
responses to pain
14.Describe Cognitive evaluative system - ANSWER mediated through the
cerebral cortex.
*overlies the individual's learned behavior concerning the experience of pain
and can modulate perception of pain
15.Describe pain threshold - ANSWER point at which a stimulus is
perceived as pain and it does not vary significantly among people or in the
same person over time
Predictor Verified Multiple Choice and Conceptual
Actual Exam Questions With Reviewed 100%
Correct Detailed Answers
Guaranteed Pass!!Current Update
1. What is Nociceptive transmission? What type of nerves are involved? -
ANSWER Mechanical, Thermal, and chemical causes of damage to the
body. carried from the periphery to the CNS. Large myelinated A-delta fibers
and small unmyelinated C fibers terminate in the substantia gelatinosa.
2. What is non-nociceptive stimulation? What type of nerves are involved? -
ANSWER touch sensors in the skin; rubbing a painful area. low intensity
stimuli. closure of partial close of the spinal gates = decreased pain
perception.
Large A-beta fibers
3. What are Nociceptors? - ANSWER free nerve endings in the afferent
PNS that selectively respond to different chemical, mechanical, and thermal
stimuli. When stimulated they cause nociceptive pain.
4. What are the 4 phases of Nociception? - ANSWER 1. Transduction
2. Transmission
3. Perception
4. Modulation
,5. What are A-delta fibers? - ANSWER lightly myelinated medium-sized
fibers that are stimulated by severe mechanical deformation and/or
extremes of temperature.
• cause reflex withdrawal of affected body part BEFORE pain sensation
is perceived
*sharp, well-localized "fast" pain sensations
6. Unmyelinated C Fibers - ANSWER Smaller unmyelinated polymodal
fibers
*Stimulated by mechanical, thermal, and chemical nociceptors
*Slowly transmit dull, aching, or burning sensations that are poorly localized
and longer lasting
7. A Beta fibers - ANSWER Large myelinated fibers
*transmit touch and vibration sensations
*Do NOT normally transmit pain, but play a role in pain modulation
8. What are the two types of fibers that transmit the nerve action potentials
generated by excitation of any of the nociceptors? - ANSWER A-delta
and C fibers
*first order sensory afferents coming into the gate at the dorsal horn of the
spinal cord.
, 9. Explain Pain transmission - ANSWER conduction of pain impulses along
the A-delta and C fibers into the dorsal horn of the spinal cord and
brainstem, thalamus, and cortex
10.Where in the CNS does pain perception occur? - ANSWER Reticular and
limbic systems and the cerebral cortex. Conscious awareness of pain.
11.Describe the Sensory-discriminative system - ANSWER Mediated by the
somatosensory cortex
*responsible for identifying the presence, character, location, and intensity of
pain
12.Describe the Affective-motivational system - ANSWER mediated
through the reticular formation, limbic system, and brainstem with
projections to the prefrontal cortex
13.*determines an individual's condition avoidance behaviors and emotional
responses to pain
14.Describe Cognitive evaluative system - ANSWER mediated through the
cerebral cortex.
*overlies the individual's learned behavior concerning the experience of pain
and can modulate perception of pain
15.Describe pain threshold - ANSWER point at which a stimulus is
perceived as pain and it does not vary significantly among people or in the
same person over time
