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PLAB 1 Keys is for PLAB-1 and UKMLA-AKT (Based on the New MLA Content-Map)
With the Most Recent Recalls and the UK Guidelines
ATTENTION: This file will be updated online on our website frequently!
(example: Version 2.7 is more recent than Version 2.6, and so on)
Key (6P features of Acute Limb Ischemia) →
1
Pain (Sudden), Pallor, Pulselessness,
Paralysis, Paraesthesia (Numbness), Perishing cold.
◙ Acute limb ischemia is a surgical emergency that requires urgent
revascularisation (Angioplasty or Open surgery) in 4-8 hours to save a limb.
Thus, it needs to be referred urgently to a vascular surgeon.
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◙ In the presence of acute limb ischemia + Irregular pulse (likely due to
Arterial Fibrillation), the likely cause of this limb ischemia is → Embolus.
Key Painless, Pulsatile mass (swelling) → Aneurysm
2
e.g. painless pulsatile mass near the groin → Femoral artery aneurysm.
Key Renal cell carcinoma can cause
3
→ Varicocele
“Bluish, bag of worms sensation, dragging pain or painless scrotal swelling”
→ Reassure or do surgery if severe persistent pain or infertility
Renal Cell Carcinoma can also cause
→ Inferior Vena Cava Syndrome
“Occlusion of IVC → pitting, non-tender edema of the lower limbs + dilated
veins on the lower abdomen”.
Key Buerger’s disease [Thromboangiitis Obliterans]
4
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◙ A small and medium vessel vasculitis.
◙ Strongly associated with smoking – especially in Young men 25-45 YO.
◙ Features
√ Extremity ischaemia: intermittent claudication, rest pain, ischaemic ulcers.
√ Superficial thrombophlebitis
√ Raynaud’s phenomenon
◙ STOP SMOKING
Example,
A 29 YO male was admitted for severe right calf pain. This pain has been
increasing over the las 3 months. He is smoker but with no Hx of HTN or DM.
O/E → loss of dorsalis pedis and posterior tibial pulsation + Non-healing ulcer
over the right first metatarsophalangeal joint.
The likely Dx → Thromboangiitis Obliterans (Buerger’s Disease).
Do not get confused:
◘ Buerger’s → Vascular → Thromboangiitis Obliterans
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“Typically, a young man with a strong Hx of smoking presenting with chronic
limb ischemia e.g. no pulse, ischemic non healing ulcer, claudication and rest
leg pain”.
◘ Berger’s → IgA Nephropathy
“Typically, a young adult with haematuria 1-2 days after an URTI”.
Key A 66 YO smoker and hypertensive patient presents with a sudden onset
5 weakness of the right arm with dysphasia that resolved within 24 hours.
♦ The likely Dx → Transient Ischemic Attack (TIA). (Resolved within 24 hours)
♦ The best next modality → Carotid Doppler Scanning
Carotid duplex should be done within 2 weeks of admission to check for carotid
artery stenosis to assess for the need of carotid endarterectomy.
When to perform Carotid endarterectomy?
√ If internal carotid artery stenosis is ≥ 50% in ♂ (Men)
√ If internal carotid artery stenosis is ≥ 70% in ♀ (Women)
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