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plab 1 (section3)

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PLAB Complete Guide & Study Pack – Your Passport to Practising Medicine in the UK Equip yourself for success in the Professional and Linguistic Assessments Board (PLAB) exams with this all‑in‑one, clinician‑curated resource. Whether you’re a fresh graduate or an experienced doctor seeking GMC registration, our pack distils everything you need into a single, high‑yield bundle.

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1 | P a g e [ V a s c u l a r ] © Copyright www.plab1keys.com (Constantly updated for online subscribers)




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Version 5.2
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Corrected, Updated, Lighter
PLAB 1 Keys is for PLAB-1 and UKMLA-AKT (Based on the New MLA Content-Map)

With the Most Recent Recalls and the UK Guidelines


ATTENTION: This file will be updated online on our website frequently!
(example: Version 2.7 is more recent than Version 2.6, and so on)




Key (6P features of Acute Limb Ischemia) →
1
Pain (Sudden), Pallor, Pulselessness,
Paralysis, Paraesthesia (Numbness), Perishing cold.


◙ Acute limb ischemia is a surgical emergency that requires urgent
revascularisation (Angioplasty or Open surgery) in 4-8 hours to save a limb.
Thus, it needs to be referred urgently to a vascular surgeon.

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◙ In the presence of acute limb ischemia + Irregular pulse (likely due to
Arterial Fibrillation), the likely cause of this limb ischemia is → Embolus.




Key Painless, Pulsatile mass (swelling) → Aneurysm
2

e.g. painless pulsatile mass near the groin → Femoral artery aneurysm.


Key Renal cell carcinoma can cause
3
→ Varicocele
“Bluish, bag of worms sensation, dragging pain or painless scrotal swelling”
→ Reassure or do surgery if severe persistent pain or infertility


Renal Cell Carcinoma can also cause
→ Inferior Vena Cava Syndrome
“Occlusion of IVC → pitting, non-tender edema of the lower limbs + dilated
veins on the lower abdomen”.


Key Buerger’s disease [Thromboangiitis Obliterans]
4



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◙ A small and medium vessel vasculitis.
◙ Strongly associated with smoking – especially in Young men 25-45 YO.


◙ Features
√ Extremity ischaemia: intermittent claudication, rest pain, ischaemic ulcers.
√ Superficial thrombophlebitis
√ Raynaud’s phenomenon


◙ STOP SMOKING


Example,
A 29 YO male was admitted for severe right calf pain. This pain has been
increasing over the las 3 months. He is smoker but with no Hx of HTN or DM.
O/E → loss of dorsalis pedis and posterior tibial pulsation + Non-healing ulcer
over the right first metatarsophalangeal joint.


The likely Dx → Thromboangiitis Obliterans (Buerger’s Disease).


Do not get confused:


◘ Buerger’s → Vascular → Thromboangiitis Obliterans


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“Typically, a young man with a strong Hx of smoking presenting with chronic
limb ischemia e.g. no pulse, ischemic non healing ulcer, claudication and rest
leg pain”.


◘ Berger’s → IgA Nephropathy
“Typically, a young adult with haematuria 1-2 days after an URTI”.


Key A 66 YO smoker and hypertensive patient presents with a sudden onset
5 weakness of the right arm with dysphasia that resolved within 24 hours.


♦ The likely Dx → Transient Ischemic Attack (TIA). (Resolved within 24 hours)


♦ The best next modality → Carotid Doppler Scanning


Carotid duplex should be done within 2 weeks of admission to check for carotid
artery stenosis to assess for the need of carotid endarterectomy.


When to perform Carotid endarterectomy?
√ If internal carotid artery stenosis is ≥ 50% in ♂ (Men)
√ If internal carotid artery stenosis is ≥ 70% in ♀ (Women)




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