NURS 7430 Advanced Pharm - Exam 1
Questions With Correct Answers
Pharmacokinetics |- |CORRECT |ANSWER✔✔-The |process |by |which |drugs |are |absorbed, |
distributed |within |the |body, |metabolized, |and |excreted.
Pharmacodynamics |- |CORRECT |ANSWER✔✔-The |process |by |which |a |medication |works |on |the |
body.
Pharmacogenomics |- |CORRECT |ANSWER✔✔-The |study |of |how |genetic |inheritance |affects |the |
body's |response |to |drugs
What |is |the |role |of |lipid-soluble, |hydrophilic |drugs, |and |simple |diffusion |in |getting |medications
|into |cells? |- |CORRECT |ANSWER✔✔-
Explain |the |concept |of |drug: |potency, |efficacy, |side-effect, |onset |of |action, |minimum |effective |
concentration, |peak |level, |therapeutic |range, |duration |of |action, |therapeutic |index, |therapeutic
|effect, |mechanism |of |action, |and |steady |state. |- |CORRECT |ANSWER✔✔-
Four |processes |involved |when |a |drug |is |taken: |- |CORRECT |ANSWER✔✔-1. |absorption
2. |distribution
3. |metabolism
4. |elimination/excretion
Explain |the |relationship |of |the |Brain-blood |barrier |in |pharmacodynamics |of |medications. |- |
CORRECT |ANSWER✔✔-Blood |vessels |(capillaries) |selectively |let |certain |substances |enter |the |
brain |tissue |and |keep |other |substances |out. |uses |only |lipid |soluble |or |transport |system
, What |determines |the |degree |of |movement |of |a |drug |between |body |compartments? |- |
CORRECT |ANSWER✔✔-1. |degree |of |hydrophila
2. |degree |lipophilicity
3. |molecular |weight
Define |and |explain |the |purpose |of |synergistic |antibiotic |combination |of |antibiotics. |Give |
examples |of |this |practice. |- |CORRECT |ANSWER✔✔-Abx |that |work |in |tandem |to |increase |
efficacy.
Ex: |amoxicillin |+ |clavulanic |acid |(Augmentin) |or |piperacillin |+ |tazobactam |(Zosyn)
Explain |why |Clavulanic |acid |is |added |to |amoxicillin. |- |CORRECT |ANSWER✔✔-to |make |it |more |
effective |against |bacteria |that |produce |beta |lactamase
Explain |the |risk |of |prolonged |QT |syndrome |and |torsade |de |pointes |and |give |examples |of |
medications |that |may |cause |this |problem. |- |CORRECT |ANSWER✔✔-Macrolides |(azithromycin, |
clarithromycin, |erythromycin)
What |would |be |appropriate |therapy |to |treat |mycoplasma |pneumonia? |- |CORRECT |
ANSWER✔✔-tetracyclines:
What |are |the |primary |adverse |effects |associated |with |antibiotics? |- |CORRECT |ANSWER✔✔-
Define |selective |toxicity |in |terms |of |antibiotic |therapy. |- |CORRECT |ANSWER✔✔-The |ability |of |
antibiotics |to |kill |bacteria |while |not |damaging |human |cells
Define |"spectrum |of |activity" |and |how |it |would |be |expressed |in |terms |of |antibiotics? |- |
CORRECT |ANSWER✔✔-
Questions With Correct Answers
Pharmacokinetics |- |CORRECT |ANSWER✔✔-The |process |by |which |drugs |are |absorbed, |
distributed |within |the |body, |metabolized, |and |excreted.
Pharmacodynamics |- |CORRECT |ANSWER✔✔-The |process |by |which |a |medication |works |on |the |
body.
Pharmacogenomics |- |CORRECT |ANSWER✔✔-The |study |of |how |genetic |inheritance |affects |the |
body's |response |to |drugs
What |is |the |role |of |lipid-soluble, |hydrophilic |drugs, |and |simple |diffusion |in |getting |medications
|into |cells? |- |CORRECT |ANSWER✔✔-
Explain |the |concept |of |drug: |potency, |efficacy, |side-effect, |onset |of |action, |minimum |effective |
concentration, |peak |level, |therapeutic |range, |duration |of |action, |therapeutic |index, |therapeutic
|effect, |mechanism |of |action, |and |steady |state. |- |CORRECT |ANSWER✔✔-
Four |processes |involved |when |a |drug |is |taken: |- |CORRECT |ANSWER✔✔-1. |absorption
2. |distribution
3. |metabolism
4. |elimination/excretion
Explain |the |relationship |of |the |Brain-blood |barrier |in |pharmacodynamics |of |medications. |- |
CORRECT |ANSWER✔✔-Blood |vessels |(capillaries) |selectively |let |certain |substances |enter |the |
brain |tissue |and |keep |other |substances |out. |uses |only |lipid |soluble |or |transport |system
, What |determines |the |degree |of |movement |of |a |drug |between |body |compartments? |- |
CORRECT |ANSWER✔✔-1. |degree |of |hydrophila
2. |degree |lipophilicity
3. |molecular |weight
Define |and |explain |the |purpose |of |synergistic |antibiotic |combination |of |antibiotics. |Give |
examples |of |this |practice. |- |CORRECT |ANSWER✔✔-Abx |that |work |in |tandem |to |increase |
efficacy.
Ex: |amoxicillin |+ |clavulanic |acid |(Augmentin) |or |piperacillin |+ |tazobactam |(Zosyn)
Explain |why |Clavulanic |acid |is |added |to |amoxicillin. |- |CORRECT |ANSWER✔✔-to |make |it |more |
effective |against |bacteria |that |produce |beta |lactamase
Explain |the |risk |of |prolonged |QT |syndrome |and |torsade |de |pointes |and |give |examples |of |
medications |that |may |cause |this |problem. |- |CORRECT |ANSWER✔✔-Macrolides |(azithromycin, |
clarithromycin, |erythromycin)
What |would |be |appropriate |therapy |to |treat |mycoplasma |pneumonia? |- |CORRECT |
ANSWER✔✔-tetracyclines:
What |are |the |primary |adverse |effects |associated |with |antibiotics? |- |CORRECT |ANSWER✔✔-
Define |selective |toxicity |in |terms |of |antibiotic |therapy. |- |CORRECT |ANSWER✔✔-The |ability |of |
antibiotics |to |kill |bacteria |while |not |damaging |human |cells
Define |"spectrum |of |activity" |and |how |it |would |be |expressed |in |terms |of |antibiotics? |- |
CORRECT |ANSWER✔✔-
