NUR 521 ADV PHARM EXAM 1 NEWEST 2025 COMPLETE
QUESTIONS AND CORRECT ANSWERS (VERIFIED ANSWERS)
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What is the prototype drug of decongestants? - ANSWER-Pseudoephedrine (Sudafed) - don't
take if abrasion in nasal mucosa
What is the PT for antihistamines? - ANSWER-Seasonal allergies
What is the PD for antihistamines? - ANSWER-Selectively blocks the effects of histamine at the
H1 receptor sites, competitively binds
What is the PK for antihistamines? - ANSWER-Oral, peak 2-6 hrs
What are the contraindications of antihistamines? - ANSWER-1st Gen create drowsiness, Preg
Class C, grapefruit juice, rifampin will decrease effects
What are the nursing roles for antihistamines? - ANSWER-Drink one glass of water, avoid
grapefruit and alcohol, CNS affects, dehumidifier, renal clearance to determine ability
What are some adverse effects of antihistamines? - ANSWER-Increased risk for viral infections,
nausea, vomiting
List some 1st gen antihistamines - ANSWER-Chlorpheniramine, clemastine, diphenhydramine
List some second gen. antihistamines - ANSWER-Cetirizine, loratadine, desloratidine
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, NUR 521 ADV PHARM EXAM 1
What is the PT for expectorants? - ANSWER-Relieves dry nonproductive cough, loosens
secretions
What is the PD for expectorants? - ANSWER-Enhance output of respiratory tract secretions by
reducing adhesiveness and surface tension in mucous
What is the PK for expectorants? - ANSWER-Oral, onset 30 min, duration 4-6 hrs
What are some adverse effects of expectorants? - ANSWER-GI symptoms, headache, dizziness
What are some contraindications of expectorants? - ANSWER-Preg Class C, smoking, alcohol
What are drug interactions of expectorants? - ANSWER-ACE-I
What is the nursing role with expectorants? - ANSWER-Drink 8 glasses of water per day, monitor
cough, humidifier, teach cough etiquette
What is the prototype drug of expectorants? - ANSWER-Guaifenisin (mucinex)
What is the PT of mucolytics? - ANSWER-Liquefy mucous -- primary CF drug!!
What is the PD of mucolytics? - ANSWER-Splits disulfide bonds that hold mucous together
What is the PK for myucolytics? - ANSWER-Administer by inhalation, VERY FAST ACTING
What are some adverse effects of mucolytics? - ANSWER-Bronchospasms, bronchoconstriction,
chest tightness, burning
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, NUR 521 ADV PHARM EXAM 1
List some contraindications of mucolytics - ANSWER-Hypersensitivity, no major drug interactions
What is the nursing role with mucolytics? - ANSWER-Ensure suction equipment, nebulizer
smells bad and need a resp. therapist there
What is the prototype drug of mucolytics? - ANSWER-Acetylcysteine (mucomyst)
What is the PT of Beta2 agonists? - ANSWER-Asthma, COPD, CAL
What is the PD of Beta2 agonists? - ANSWER-Activate beta 2 receptors in SMCs of lungs; depress
histamine release
What is the PK for beta2 agonists? - ANSWER-SABA: short acting (rescue inhaler) peakd 30-60
min, not for prophylaxis
LABA: long acting, IV, oral, inhalers, can be in combination with steroid (black box warning)
What are the rules for using MDI's with beta2 agonists? - ANSWER-Separate each puff by 1 min,
3 min in between two different medications, 2 inches away from mouth or with a spacer, wash
mouth immediately after use
What are some adverse effects of beta2 agonists? - ANSWER-Normally well tolerated but can
cause tachycardia, palpations, angina, tremors (activating beta2 receptors in skeletal muscle)
List some contraindications for beta2 agonists - ANSWER-Decongestants, cardiac disorders, Htn
What are the nursing roles with beta2 agonists? - ANSWER-Wash mouth after use
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, NUR 521 ADV PHARM EXAM 1
List the main prototype beta2 agonists and one other example. - ANSWER-Albuterol
Solemederol
What is the PT for anticholinergics? - ANSWER-COPD/CAL
What is the PD for anticholinergics? - ANSWER-Blocks receptors that normally house
acetylcholine
What is the PK for anticholinergics? - ANSWER-30 min after dose, peak 3 hrs, persists 24 hours
What are some adverse effects of anticholinergics? - ANSWER-Minimal systemic effects, dry
mouth, CV events can occur
What are contraindications of anticholinergics? - ANSWER-Peanut allergy after combivent
List the main Bronchodilators. - ANSWER-B-Beta2 agonists
A-Anticholinergic agents
M-Methylxanthine Derivatives
List the main Anti-Inflammatories - ANSWER-S-Sys. Glucocorticoids/Corticosteriods
L-Leukotriene Modifiers
M-Mast Cell Stabilizers
List the categories of Upper Resp. drugs - ANSWER-D-Decongestants
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