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Q: The LPN is about to give 100 mg of metoprolol to a patient. Before administering, which is
most important to check?
A) Respiratory rate
B) Blood sugar
C) Pulse
D) Temperature
Answer: C — Pulse
Rationale: Beta-blockers can cause bradycardia; hold medication and inform provider if HR is
below 60 bpm.
Q: A patient requires a high dose of a new antihypertensive with a significant first-pass effect.
What does “first-pass effect” mean?
A) Medication circulates multiple times before effect
B) It is excreted in urine before working
C) It is extensively metabolized in the liver
D) It becomes more effective after repeated doses
Answer: C — Extensively metabolized in the liver
Rationale: A strong first-pass effect means much of the drug is removed before reaching
systemic circulation.
Q: A patient asks how sulfamethoxazole-trimethoprim (SMZ/TMP) works. The nurse responds it:
A) Acts as an anesthetic with trimethoprim
B) Is protein-bound and displaces trimethoprim
C) Increases excretion to enhance bladder response
D) Has a synergistic effect against both G+ and G– organisms
Answer: D — Synergistic effect against gram-positive and negative organisms
Rationale: Sulfamethoxazole and trimethoprim work together to block bacterial folate
synthesis.
, 4. Opioid Side Effects
Q: What is the most common side effect of oxycodone?
A) Lower extremity paresthesia
B) Intracranial hypertension
C) Headaches
D) Drowsiness
Answer: D — Drowsiness
Rationale: Opioids frequently cause sedation and drowsiness in patients.
5. Electrolyte & Cardiac Effects – Furosemide
Q: A patient on furosemide for heart failure is at risk of which electrolyte imbalance?
A) Hyperkalemia
B) Hypernatremia
C) Hypokalemia
D) Hyponatremia
Answer: C — Hypokalemia
Rationale: Loop diuretics increase potassium excretion, leading to decreased serum levels.
6. Digoxin Administration
Q: Prior to a scheduled dose of digoxin, the patient’s apical pulse is 53 bpm. The nurse’s next
action should be:
A) Hold the dose
B) Administer as scheduled
C) Notify the charge nurse
D) Contact provider for dose adjustment
Answer: A — Hold the dose
Rationale: A low heart rate warrants withholding digoxin and notifying the provider.
7. Respiratory Medication Teaching
Q: A patient taking methylphenidate reports difficulty sleeping. The best nurse response is:
A) “Give the medication before 4 pm.”