WGU D116 Unit 8 OA Review with correct answers 2025
A nursing student asks for clarification on the differences between the mechanisms of
spontaneous mutation and conjugation in acquired resistance of microbes.
Which statement is correct? - correct answerSpontaneous mutation leads to resistance to only
one antimicrobial agent
A patient receiving a cephalosporin develops a secondary intestinal infection caused by
Clostridium difficile.
What is an appropriate treatment for this patient? - correct answerDiscontinuing the
cephalosporin and beginning flagyl
A patient is diagnosed with a lung infection caused by Pseudomonas aeruginosa. The culture
and sensitivity report shows sensitivity to all aminoglycosides. The provider knows that the rate
of resistance to gentamicin is common in this hospital.
Which medication should the provider be expected to order? - correct answerAmikacin
When resistance to gentamicin and tobramycin is common, amikacin is the drug of choice for
the initial treatment of aminoglycoside-sensitive infections
A child with otitis media has had three ear infections in the past year. The child has just
completed a ten-day course of amoxicillin with no improvement. The parent asks the provider
why this drug is not working because it has worked in the past.
What should the provider tell the patient? - correct answer"The bacteria have synthesized
penicillinase"
Beta-lactamases are enzymes that cleave the beta-lactam ring and render the PCN inactive
(amoxicillin)
Pt will need to start augmentin
, A patient who is taking acetaminophen for pain wants to know why it does not cause
gastrointestinal upset as other over-the-counter pain medications do.
Which property of acetaminophen is the most likely explanation for this? - correct answerIt has
minimal effects at peripheral sites
Tylenol central effects
NSAIDs peripheral effects
A patient who has arthritis has been taking ibuprofen and a glucocorticoid medication. The
patient reports having tarry stools but denies gastric pain.
Which action by the provider is correct? - correct answerPrescribing an antiulcer medication
Glucocorticoid therapy, especially when combined with NSAIDs, can increase the risk of gastric
ulcer and possibly bleeding
A patient will begin taking hydroxychloroquine for rheumatoid arthritis. The patient is currently
taking high-dose NSAIDs and methotrexate.
What should the patient be taught about hydroxychloroquine? - correct answerAn eye exam is
necessary at the beginning of therapy with this drug
Can cause retinal damage - eye exam at the onset of treatment as well as every 6 months during
treatment
A patient with gout who has increasingly frequent acute gouty attacks will begin receiving
allopurinol and colchicine.
Which statement should be included when teaching the patient about this drug regimen? -
correct answer"You will take both drugs initially and then stop taking colchicine"
Colchicine is used for prophylaxis when urate-lowering drugs (allopurinal) are initiated because
gouty episodes often increase during this time.
A nursing student asks for clarification on the differences between the mechanisms of
spontaneous mutation and conjugation in acquired resistance of microbes.
Which statement is correct? - correct answerSpontaneous mutation leads to resistance to only
one antimicrobial agent
A patient receiving a cephalosporin develops a secondary intestinal infection caused by
Clostridium difficile.
What is an appropriate treatment for this patient? - correct answerDiscontinuing the
cephalosporin and beginning flagyl
A patient is diagnosed with a lung infection caused by Pseudomonas aeruginosa. The culture
and sensitivity report shows sensitivity to all aminoglycosides. The provider knows that the rate
of resistance to gentamicin is common in this hospital.
Which medication should the provider be expected to order? - correct answerAmikacin
When resistance to gentamicin and tobramycin is common, amikacin is the drug of choice for
the initial treatment of aminoglycoside-sensitive infections
A child with otitis media has had three ear infections in the past year. The child has just
completed a ten-day course of amoxicillin with no improvement. The parent asks the provider
why this drug is not working because it has worked in the past.
What should the provider tell the patient? - correct answer"The bacteria have synthesized
penicillinase"
Beta-lactamases are enzymes that cleave the beta-lactam ring and render the PCN inactive
(amoxicillin)
Pt will need to start augmentin
, A patient who is taking acetaminophen for pain wants to know why it does not cause
gastrointestinal upset as other over-the-counter pain medications do.
Which property of acetaminophen is the most likely explanation for this? - correct answerIt has
minimal effects at peripheral sites
Tylenol central effects
NSAIDs peripheral effects
A patient who has arthritis has been taking ibuprofen and a glucocorticoid medication. The
patient reports having tarry stools but denies gastric pain.
Which action by the provider is correct? - correct answerPrescribing an antiulcer medication
Glucocorticoid therapy, especially when combined with NSAIDs, can increase the risk of gastric
ulcer and possibly bleeding
A patient will begin taking hydroxychloroquine for rheumatoid arthritis. The patient is currently
taking high-dose NSAIDs and methotrexate.
What should the patient be taught about hydroxychloroquine? - correct answerAn eye exam is
necessary at the beginning of therapy with this drug
Can cause retinal damage - eye exam at the onset of treatment as well as every 6 months during
treatment
A patient with gout who has increasingly frequent acute gouty attacks will begin receiving
allopurinol and colchicine.
Which statement should be included when teaching the patient about this drug regimen? -
correct answer"You will take both drugs initially and then stop taking colchicine"
Colchicine is used for prophylaxis when urate-lowering drugs (allopurinal) are initiated because
gouty episodes often increase during this time.
