BCH 4053 FINAL EXAM QUIZLET
COMBINED QUESTIONS
At which pH value would histidine (pKa of 1.8, 6.0, and 9.2) be found with a net negative charge?
a. 1.0
b. 8.0
c. 12.0
d. 11.0
e. none of the above ANS: d. 11.0
All are structural and functional advantages to quaternary structure EXCEPT:
A. Cooperativity
B. Stability
C. Brining catalytic sites together
D. Genetic economy and efficiency
E. All are true ANS: E. All are true
Which of the following lipids is correctly defined?
A. Triacylglycerol: formed from glycerol and 3 fatty acids, primary lipid of membranes
,B. Phospholipid: contains glycerol with 2 fatty acids and a phosphate, very often forms bilayers
C. Cholesterol: the primary component of "saturated" fats
D. Palmitic acid: the most commonly produced unsaturated fatty acid in animals ANS: B. Phospholipid:
contains glycerol with 2 fatty acids and a phosphate, very often forms bilayers
The amino acid residue most likely to be found in a beta turn is:
A. glycine
B. alanine
C. valine
D. glutamic acid
E. leucine ANS: A. Glycine
Why should the core of most globular and membrane proteins consist almost entirely of alpha helices
and beta sheets?
A. Hydrogen bonded structures must be kept away from the water solvent
B. Highly polar N-H and C=O moieties of the peptide backbone must be neutralized in the hydrophobic
core of the protein
C. Hydrogen bonding only occurs in the core of proteins
D. Trapped water stabilizes the helix and sheet structures
,E. None are true ANS: B. Highly polar N-H and C=O moieties of the peptide backbone must be
neutralized in the hydrophobic core of the protein
Bacteria in a colder environment would have membranes with
A. More unsaturated fatty acids
B. More saturated fatty acids
C. Higher rates of metabolism
D. Higher sphingolipid content
E. Higher cholesterol content ANS: A. More unsaturated fatty acids
To make a buffer at pH 7.4, which two compounds would you choose? (pKa for phosphoric acid are 2.1,
6.9, 12.4)
A. Phosphoric acid and disodium hydrogen phosphate
B. HCl and disodium hydrogen phosphate
C. Disodium hydrogen phosphate and NaOH
D. Disodium hydrogen phosphate and trisodium phosphate
E. Disodium hydrogen phosphate and sodium hydrogen phosphate ANS: E. Disodium hydrogen
phosphate and sodium hydrogen phosphate
The ∆Gº for ATP hydrolysis and PEP hydrolysis are -30.5 kJ/mole and -61.9 kJ/mole, respectively. Find ∆G
of:
PEP + ADP ATP + pyruvate
A. -92.4 kJ/mole
, B. -31.4 kJ/mole
C. -2.4 kJ/mole
D. +2.4 kJ/mole
E. Cannot answer the question ANS: B. -31.4 kJ/mole
All of the following are true except:
A. Asp and Asn are acidic amino acids
B. Ala and val are neutral, nonpolar amino acids
C. Ser and gln are polar, uncharged amino acids
D. Lys and arg are basic amino acids
E. Tyr and phe are aromatic amino acids ANS: A. Asp and Asn are acidic amino acids
Which of the following has more than one chiral carbon?
A. ser
B. lys
C. thr
D. cys
E. asp ANS: C. thr
COMBINED QUESTIONS
At which pH value would histidine (pKa of 1.8, 6.0, and 9.2) be found with a net negative charge?
a. 1.0
b. 8.0
c. 12.0
d. 11.0
e. none of the above ANS: d. 11.0
All are structural and functional advantages to quaternary structure EXCEPT:
A. Cooperativity
B. Stability
C. Brining catalytic sites together
D. Genetic economy and efficiency
E. All are true ANS: E. All are true
Which of the following lipids is correctly defined?
A. Triacylglycerol: formed from glycerol and 3 fatty acids, primary lipid of membranes
,B. Phospholipid: contains glycerol with 2 fatty acids and a phosphate, very often forms bilayers
C. Cholesterol: the primary component of "saturated" fats
D. Palmitic acid: the most commonly produced unsaturated fatty acid in animals ANS: B. Phospholipid:
contains glycerol with 2 fatty acids and a phosphate, very often forms bilayers
The amino acid residue most likely to be found in a beta turn is:
A. glycine
B. alanine
C. valine
D. glutamic acid
E. leucine ANS: A. Glycine
Why should the core of most globular and membrane proteins consist almost entirely of alpha helices
and beta sheets?
A. Hydrogen bonded structures must be kept away from the water solvent
B. Highly polar N-H and C=O moieties of the peptide backbone must be neutralized in the hydrophobic
core of the protein
C. Hydrogen bonding only occurs in the core of proteins
D. Trapped water stabilizes the helix and sheet structures
,E. None are true ANS: B. Highly polar N-H and C=O moieties of the peptide backbone must be
neutralized in the hydrophobic core of the protein
Bacteria in a colder environment would have membranes with
A. More unsaturated fatty acids
B. More saturated fatty acids
C. Higher rates of metabolism
D. Higher sphingolipid content
E. Higher cholesterol content ANS: A. More unsaturated fatty acids
To make a buffer at pH 7.4, which two compounds would you choose? (pKa for phosphoric acid are 2.1,
6.9, 12.4)
A. Phosphoric acid and disodium hydrogen phosphate
B. HCl and disodium hydrogen phosphate
C. Disodium hydrogen phosphate and NaOH
D. Disodium hydrogen phosphate and trisodium phosphate
E. Disodium hydrogen phosphate and sodium hydrogen phosphate ANS: E. Disodium hydrogen
phosphate and sodium hydrogen phosphate
The ∆Gº for ATP hydrolysis and PEP hydrolysis are -30.5 kJ/mole and -61.9 kJ/mole, respectively. Find ∆G
of:
PEP + ADP ATP + pyruvate
A. -92.4 kJ/mole
, B. -31.4 kJ/mole
C. -2.4 kJ/mole
D. +2.4 kJ/mole
E. Cannot answer the question ANS: B. -31.4 kJ/mole
All of the following are true except:
A. Asp and Asn are acidic amino acids
B. Ala and val are neutral, nonpolar amino acids
C. Ser and gln are polar, uncharged amino acids
D. Lys and arg are basic amino acids
E. Tyr and phe are aromatic amino acids ANS: A. Asp and Asn are acidic amino acids
Which of the following has more than one chiral carbon?
A. ser
B. lys
C. thr
D. cys
E. asp ANS: C. thr
