FINAL VERSION 1 EXAM 2025/2026 WITH
ACTUAL CORRECT QUESTIONS AND
VERIFIED DETAILED ANSWERS
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What are some uses in research of guinea pigs?
Cancer
Toxicities
Behavior
Dematologcal
pharmaceuticals
What is pregnancy toxemia? How can it be treated?
Pregnancy toxemia is a condition when the mother is in an negative energy balance due to the
pups developing. The mother is not getting enough energy through food and metabolism to
keep up. We treat this with glucose/nutrition supplementation.
How do we sex mice?
By the anogenital distance, males are 1 ½ X longer than that of females
Guinea Pig IM injection
Restrain the animal appropriately. Place thumb of non-dominant hand on the vertebrae and
index finger just behind the most caudal rib. Find the epaxial muscle and lift it against your
thumb. With dominant hand, place syringe perpendicular to the muscle. You will need to move
your hand slightly to look for blood when aspirating.
Mouse SQ Injection
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,Restrain the animal appropriately
Place the needle, using a cranial to caudal approach at a 40-45 degree angle into the scruff
between the ears.
What type of ovulator is a mouse?
Spontaneous
Is a mouse covered by the AWA?
No
What is a mouse used in research for?
Cancer
Toxicities
Pharmaceuticals
Breeding
Behavior
What is Malocclusion? What is the cause? How can it be prevented?
Overgrown teeth or where the jaws do not match up correctly
Malocclusion is most often caused by the animal not wearing teeth down adequately due to not
having appropriate substrates to chew on
Offering appropriate enrichment to allow the animal to chew.
Where is the gerbil's scent gland?
ventral midline, just caudal to the Xyphoid Process or Umbilicus
Where is the hamster's scent gland?
lateral flank, just proximal to the hip
True or False - Rabbit gender cannot be determined by measuring the anogenital distance
True
Rabbit IV Injection
Rabbit needs to be restrained in a mechanical restrainer or a towel.
Ear is held in such a way that the rabbit cannot pull it out of the hand, and the needle can be
placed with no angle. A tourniquet or hand is used to occlude the vessel.
A small guage needle such as a 27g ½" is threaded into the caudal marginal ear vein distal to
proximal direction.
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, Once blood is seen in the hub, a hematocrit tube is placed into the hub to collect the blood.
When blood is collected, the occlusion is released, digital pressure is applied and the needle is
removed.
The venipuncture site should be held for 20-30 seconds or until bleeding stops.
What type of ovulator is a rabbit?
Induced
Is the rabbit covered by the AWA?
Yes
What are rabbits used for in research
Cancer
Behavior
Ocular
Pharmceuticals
What is Snuffles? How can the clinical signs? Name the specific agent.
Snuffles is also called Pasteurellosis. It is an upper respiratory infection caused by Pasteurella
multocida, a bacteria.
Runny nose, crusty eyes and in advanced cases inner ear infections and circling is seen.
True or False - The majority of non-human primates currently used in American research
facilities are not wild-caught, but instead are bred and available through domestic suppliers.
True
True or False - Non-human primate tuberculosis (TB) testing is usually performed via
intradermal injection of TB antigen into the skin of the chest region. This is due to the ease of
reaction visualization at this site.
False, the eyelid
A very contagious bacterial enteric pathogen occurs often in nun-human primate colonies.
Pathogenesis of this disease involves bloody and mucoid diarrhea, resulting in fatigue and
dehydration. Circle the correct etiology:
Shigella
What is the term for a period of separation for animals newly introduced to a research facility
where actions are completed (testing, isolation from the research colony, acclimatization to
surroundings, etc) to ensure the addition of suitable individuals to the colony:
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