7/13/25, 11:25
AM
NUR 641 E FINAL EXAM STUDY GUIDE GRAND
CANYON UNIVERSITY 2025|ACTUAL EXAM SET
QUESTIONS AND VERIFIED ANSWERS (CORRECT
SOLUTIONS)
Terms in this set (181)
absorption, Pharmacokinetics involves
distribution,
metabolism,
excretion
absorption from Pharmacokinetic absorption
the
administration
site either
directly or
indirectly in the
blood plasma
reversibly or Parmacokinetic distribution
irreversibly move
1/
44
,7/13/25, 11:25
AM
from the
bloodstream into
the interstitial
and
intracellular fluid
biotransformed Pharmacokinetics metabolism
via hepatic
metabolism or by
other tissue
1. highest Intravenous medications
bioavailability
2. places entire
does into venin
thus
bypassing
absorption
3. avoids hepatic
first pass
metabolism in
the liver
2/
44
,7/13/25, 11:25
AM
usually reached steady state medication
within 4-5 half
lives of the drug
1. the time drug half life
required for the
elimination
process to reduce
2.the
concentration of
the drug to one
half what it was at
initial
administration
3. determines
drug frequency
4. predicts length of
toxic effects
5. constant first
order
pharmacokinetics
of a drug
drug is zero order (nonlinear)
metabolized at a
3/
44
, 7/13/25, 11:25
AM
constant rate per
unit
metabolizes CYP3A4
50% drugs
inhibit:
grapefruit
juice
- increase drug ->
adverse effects
may have enhanced
activity with any
other CYP3A4
1. discovery or Six steps in drug development process
laboratory for
development
2. Phase 1 begins with
animal testing
3. phase 2 human
subjects
4. compare drug
to placebo or
other drug that
is effective
4/
44
AM
NUR 641 E FINAL EXAM STUDY GUIDE GRAND
CANYON UNIVERSITY 2025|ACTUAL EXAM SET
QUESTIONS AND VERIFIED ANSWERS (CORRECT
SOLUTIONS)
Terms in this set (181)
absorption, Pharmacokinetics involves
distribution,
metabolism,
excretion
absorption from Pharmacokinetic absorption
the
administration
site either
directly or
indirectly in the
blood plasma
reversibly or Parmacokinetic distribution
irreversibly move
1/
44
,7/13/25, 11:25
AM
from the
bloodstream into
the interstitial
and
intracellular fluid
biotransformed Pharmacokinetics metabolism
via hepatic
metabolism or by
other tissue
1. highest Intravenous medications
bioavailability
2. places entire
does into venin
thus
bypassing
absorption
3. avoids hepatic
first pass
metabolism in
the liver
2/
44
,7/13/25, 11:25
AM
usually reached steady state medication
within 4-5 half
lives of the drug
1. the time drug half life
required for the
elimination
process to reduce
2.the
concentration of
the drug to one
half what it was at
initial
administration
3. determines
drug frequency
4. predicts length of
toxic effects
5. constant first
order
pharmacokinetics
of a drug
drug is zero order (nonlinear)
metabolized at a
3/
44
, 7/13/25, 11:25
AM
constant rate per
unit
metabolizes CYP3A4
50% drugs
inhibit:
grapefruit
juice
- increase drug ->
adverse effects
may have enhanced
activity with any
other CYP3A4
1. discovery or Six steps in drug development process
laboratory for
development
2. Phase 1 begins with
animal testing
3. phase 2 human
subjects
4. compare drug
to placebo or
other drug that
is effective
4/
44
