INSTITUTION NAME
MEDICINAL
CHEMISTRY
ASSIGNMENT
FIRSTNAME
LASTNAME
COURSE
1 2 1 3 2 2 0 6 1 00 1
, C H E M O T H E R A P E U T I C
A G E N T S
CHEMOTHERAPEUTIC AGENTS
Chemotherapy is the therapeutic use of drugs to treat infectious diseases
by selectively targeting and destroying harmful parasites, pathogens, or
microorganisms while minimizing damage to the host's tissues. The drugs
employed to combat these pathogenic organisms are collectively referred
to as chemotherapeutic agents.
Disease Malaria
Antimalarials
Commonly used drugs Chloroquine
Disease Bacterial infection
Antibiotics
Commonly used drugs Amoxicillin
Disease Tuberculosis
Antitubercular
Commonly used drugs Isoniazid
Class
of
drugs
Disease Trypanosomiasis
Antiprotozoals
Commonly used drugs Metronidazole
Disease Bacterial infection
Antibacterial
Commonly used drugs Sulphanilamide
Disease Helminths
Anthelmintics
Commonly used drugs Albendazole
, ANTIMALARIALS
Drugs thattreat orprevent malaria by targeting and disrupting the life
cycle of Plasmodium parasites, inhibiting their replication or
metabolism, and eliminating them from the body.
Mode of Action :
Inhibits heme polymerization, leading to toxic heme
accumulation in parasites.
Disrupts parasite DNA and metabolic processes.
Results in parasite death and clearance from the bloodstream.
Example: Chloroquine
Structure of Chloroquine
ANTIBIOTICS
Drugs that combat bacterial infections by interfering with bacterial
processes like cell wall synthesis, protein production, or DNA replication,
either killing the bacteria or stopping their growth.
Mode of Action :
Inhibits bacterial cell wall synthesis or protein synthesis.
Disrupts bacterial DNA replication or metabolism.
Results in bacterial cell death or growth inhibition.
Example: Amoxicillin
Structure of Amoxicillin