NR 565 PHARMACOLOGY FINAL EXAM
CURRENTLY TESTING VERSIONS 2025
WITH QUESTIONS AND CORRECT
DETAILED ANSWERS/FROM A VERIFIED
SOURCE FOR GUARANTEED PASS!!!
Signs and symptoms of hypothyroidism - CORRECT ANSWER-Face is
pale, puffy, and expressionless.
Skin is cold and dry.
hair is brittle, and hair loss occurs.
Heart rate and temperature are lowered. The patient lethargy, fatigue,
and intolerance to cold.
Mentation may be impaired.
Signs and symptoms of hyperthyroidism - CORRECT ANSWER-Heart
Rate is Rapid; Possible arrhythmia/angina
Nervousness, insomnia, rapid thought flow, and rapid speech
Skeletal muscles may weaken and atrophy
,Metabolic rate is raised, resulting in increased heat production,
increased body temperature, intolerance to heat, and skin that is warm
and moist
Weight loss occurs if caloric intake fails to match the increase in
metabolic rate
Severe hypothyroidism - CORRECT ANSWER-Myxedema
Hypothyroid Treatment - CORRECT ANSWER-Levothyroxine is the
drug of choice for most patients who require thyroid hormone
replacement.
Levothyroxine (Synthroid) Therapeutic Goal - CORRECT ANSWER-
Resolution of signs and symptoms of hypothyroidism and restoration of
normal laboratory values for serum thyroid-stimulating hormone (TSH)
and free thyroxine (T4).
Major forms of hyperthyroidism - CORRECT ANSWER-Graves disease
and toxic nodular goiter (also known as Plummer disease).
Graves Disease - CORRECT ANSWER-Most common cause of excessive
thyroid hormone secretion
,What adjunctive therapy is good to prescribe to control symptoms of
hyperthyroidism other than thyroid specific medications? - CORRECT
ANSWER-β-Blockers and nonradioactive iodine may be used as
adjunctive therapy.
β-Blockers suppress tachycardia by blocking β-receptors on the heart.
Nonradioactive iodine inhibits synthesis and release of thyroid
hormones.
Monitoring needs and intervals for Levothyroxine - CORRECT
ANSWER-Check TSH 6-8 weeks after initiating therapy and after any
dosage change.
Check TSH at least once a year after serum TSH is stabilized.
Hyperthyroid Treatment - CORRECT ANSWER-thionamide drugs—
methimazole and propylthiouracil (PTU)—suppress synthesis of thyroid
hormones.
Methimazole Therapeutic Goal - CORRECT ANSWER-(1) reduction of
thyroid hormone production in Graves' disease, (2) control of
hyperthyroidism until the effects of radiation on the thyroid become
manifest, (3) suppression of thyroid hormone production before
subtotal thyroidectomy, (4) treatment of thyrotoxic crisis.
, Monitoring needs and intervals for Methimazole - CORRECT ANSWER-
Check CBC with differential if signs or symptoms of infection. Check
LFTs if signs or symptoms of liver dysfunction.
High Risk Patients for Methimazole - CORRECT ANSWER-Should be
avoided in the first trimester of pregnancy.
Methimazole Toxicity - CORRECT ANSWER-Agranulocytosis is the
most dangerous toxicity.
PTU High Risk Warning - CORRECT ANSWER-Carries a risk for liver
toxicity. Although rare, the FDA recommends against using as a first-
line treatment due to potential for hepatic toxicity.
Effects of maternal hypothyroidism on offspring and appropriate
patient teaching related to need for treatment. - CORRECT ANSWER-
Can cause delay in mental development and derangement of growth. In
the absence of thyroid hormones, the child develops a large and
protruding tongue, potbelly, and dwarfish stature. Development of the
nervous system, bones, teeth, and muscles is impaired.
Congenital Hypothyroidism Treatment - CORRECT ANSWER-requires
replacement therapy with thyroid hormones. If treatment is initiated
within a few days of birth, physical and mental development will be
normal.
CURRENTLY TESTING VERSIONS 2025
WITH QUESTIONS AND CORRECT
DETAILED ANSWERS/FROM A VERIFIED
SOURCE FOR GUARANTEED PASS!!!
Signs and symptoms of hypothyroidism - CORRECT ANSWER-Face is
pale, puffy, and expressionless.
Skin is cold and dry.
hair is brittle, and hair loss occurs.
Heart rate and temperature are lowered. The patient lethargy, fatigue,
and intolerance to cold.
Mentation may be impaired.
Signs and symptoms of hyperthyroidism - CORRECT ANSWER-Heart
Rate is Rapid; Possible arrhythmia/angina
Nervousness, insomnia, rapid thought flow, and rapid speech
Skeletal muscles may weaken and atrophy
,Metabolic rate is raised, resulting in increased heat production,
increased body temperature, intolerance to heat, and skin that is warm
and moist
Weight loss occurs if caloric intake fails to match the increase in
metabolic rate
Severe hypothyroidism - CORRECT ANSWER-Myxedema
Hypothyroid Treatment - CORRECT ANSWER-Levothyroxine is the
drug of choice for most patients who require thyroid hormone
replacement.
Levothyroxine (Synthroid) Therapeutic Goal - CORRECT ANSWER-
Resolution of signs and symptoms of hypothyroidism and restoration of
normal laboratory values for serum thyroid-stimulating hormone (TSH)
and free thyroxine (T4).
Major forms of hyperthyroidism - CORRECT ANSWER-Graves disease
and toxic nodular goiter (also known as Plummer disease).
Graves Disease - CORRECT ANSWER-Most common cause of excessive
thyroid hormone secretion
,What adjunctive therapy is good to prescribe to control symptoms of
hyperthyroidism other than thyroid specific medications? - CORRECT
ANSWER-β-Blockers and nonradioactive iodine may be used as
adjunctive therapy.
β-Blockers suppress tachycardia by blocking β-receptors on the heart.
Nonradioactive iodine inhibits synthesis and release of thyroid
hormones.
Monitoring needs and intervals for Levothyroxine - CORRECT
ANSWER-Check TSH 6-8 weeks after initiating therapy and after any
dosage change.
Check TSH at least once a year after serum TSH is stabilized.
Hyperthyroid Treatment - CORRECT ANSWER-thionamide drugs—
methimazole and propylthiouracil (PTU)—suppress synthesis of thyroid
hormones.
Methimazole Therapeutic Goal - CORRECT ANSWER-(1) reduction of
thyroid hormone production in Graves' disease, (2) control of
hyperthyroidism until the effects of radiation on the thyroid become
manifest, (3) suppression of thyroid hormone production before
subtotal thyroidectomy, (4) treatment of thyrotoxic crisis.
, Monitoring needs and intervals for Methimazole - CORRECT ANSWER-
Check CBC with differential if signs or symptoms of infection. Check
LFTs if signs or symptoms of liver dysfunction.
High Risk Patients for Methimazole - CORRECT ANSWER-Should be
avoided in the first trimester of pregnancy.
Methimazole Toxicity - CORRECT ANSWER-Agranulocytosis is the
most dangerous toxicity.
PTU High Risk Warning - CORRECT ANSWER-Carries a risk for liver
toxicity. Although rare, the FDA recommends against using as a first-
line treatment due to potential for hepatic toxicity.
Effects of maternal hypothyroidism on offspring and appropriate
patient teaching related to need for treatment. - CORRECT ANSWER-
Can cause delay in mental development and derangement of growth. In
the absence of thyroid hormones, the child develops a large and
protruding tongue, potbelly, and dwarfish stature. Development of the
nervous system, bones, teeth, and muscles is impaired.
Congenital Hypothyroidism Treatment - CORRECT ANSWER-requires
replacement therapy with thyroid hormones. If treatment is initiated
within a few days of birth, physical and mental development will be
normal.
