APICOMPLEXA
APICOMPLEXA
Intermediate Host Man
Infective Stage to Intermediate Host Sporozoite
Habitat in Man Liver, RBC
Definitive or Final Host Mosquito (Female Anopheles)
Infective Stage to Final Host Gametocyte
Habitat in Mosquito Digestive Tract
PLASMODIUM FALCIPARUM PLASMODIUM VIVAX PLASMODIUM MALARIAE
Ring Forms - Infect young & old RBC slightly enlarged - Infect young RBC but enlarged - Infect old RBC
- Reticulocytes (young
RBC)
- Delicate small ring form - Signet ring - Smaller ring
- Multiple ring forms in single RBC
- 2 chromatin dots - Heavy chromatin dot - Heavy chromatin dot
(Bird’s eye)
- Marginal forms (accole/applique) - ⅓ of RBC diameter - ⅛ of cell
Developing Trophozoite - Ameboid - Ameboid - Band-shaped
- Compact - Large chromatin - Basket form
- Giemsa stain (reddish orange) - Smaller RBC
- Cytoplasmic content (eosinophiliic)
- Nuclear content (basophilic)
Schizonts - 8 to 36 merozoites - 12 to 24 merozoites - 6 to 12 merozoites
- Most prevalent in philippines - Most prevalent worldwide & - Rosette or fuit pie
- Presence indicates severe malaria philippines appearance
- Hypnozoites dormant - Flower-like
- Brown pigment
, Gametocyte - Microgametocyte (sausage, diffuse chromatin) - Microgametocyte (round, - Microgametocyte (smaller
surrounded by halo, pink to than Vivax)
purple)
- Macrogametocyte (crescent, compact - Macrogametoyte (round, - Macrogametocyte
chromatin) eccentric, chromatin mass, (smaller than Vivax)
- Highest number of nucleus light brown) - Round, fine granular
Stipplings - Maurer’s Cleft (metabolism/genetic materials - Schuffner’s Dots - Ziemman’s Dots
product)
- Schuffner’s Dots (hemoglobin metabolism
product)
Febrile or Erythrocytic Cycle - Malignant Tertian (36 to 48 hrs) - Benign Tertian (48 hrs) - Quartan Malaria (72 hrs)
IMPORTANT BUT WAS NOT INCLUDED HERE: LIFE CYCLE
APICOMPLEXA
Intermediate Host Man
Infective Stage to Intermediate Host Sporozoite
Habitat in Man Liver, RBC
Definitive or Final Host Mosquito (Female Anopheles)
Infective Stage to Final Host Gametocyte
Habitat in Mosquito Digestive Tract
PLASMODIUM FALCIPARUM PLASMODIUM VIVAX PLASMODIUM MALARIAE
Ring Forms - Infect young & old RBC slightly enlarged - Infect young RBC but enlarged - Infect old RBC
- Reticulocytes (young
RBC)
- Delicate small ring form - Signet ring - Smaller ring
- Multiple ring forms in single RBC
- 2 chromatin dots - Heavy chromatin dot - Heavy chromatin dot
(Bird’s eye)
- Marginal forms (accole/applique) - ⅓ of RBC diameter - ⅛ of cell
Developing Trophozoite - Ameboid - Ameboid - Band-shaped
- Compact - Large chromatin - Basket form
- Giemsa stain (reddish orange) - Smaller RBC
- Cytoplasmic content (eosinophiliic)
- Nuclear content (basophilic)
Schizonts - 8 to 36 merozoites - 12 to 24 merozoites - 6 to 12 merozoites
- Most prevalent in philippines - Most prevalent worldwide & - Rosette or fuit pie
- Presence indicates severe malaria philippines appearance
- Hypnozoites dormant - Flower-like
- Brown pigment
, Gametocyte - Microgametocyte (sausage, diffuse chromatin) - Microgametocyte (round, - Microgametocyte (smaller
surrounded by halo, pink to than Vivax)
purple)
- Macrogametocyte (crescent, compact - Macrogametoyte (round, - Macrogametocyte
chromatin) eccentric, chromatin mass, (smaller than Vivax)
- Highest number of nucleus light brown) - Round, fine granular
Stipplings - Maurer’s Cleft (metabolism/genetic materials - Schuffner’s Dots - Ziemman’s Dots
product)
- Schuffner’s Dots (hemoglobin metabolism
product)
Febrile or Erythrocytic Cycle - Malignant Tertian (36 to 48 hrs) - Benign Tertian (48 hrs) - Quartan Malaria (72 hrs)
IMPORTANT BUT WAS NOT INCLUDED HERE: LIFE CYCLE
