Name: Sarah Thompson
Age: 55 years
Gender: Female
Chief Complaint: Acute confusion for 6 hours
Setting: Emergency department with full imaging (CT, MRI) and
laboratory capabilities
Date and Time: July 16, 2025, 12:00 PM EAT
Case Overview
This case study, designed for Week #8 of the i-Human platform, focuses
on a 55-year-old female presenting to the emergency department with
acute confusion of 6 hours’ duration, requiring a comprehensive clinical
evaluation and management plan in an acute care setting with
advanced diagnostic capabilities. The objectives are to:
, Obtain a comprehensive history (from the patient, if possible, and
collateral sources, e.g., family) to characterize the onset, duration,
and associated symptoms of acute confusion, considering age-
related risk factors and comorbidities.
Perform a targeted neurologic, mental status, and systemic
physical examination to identify urgent causes of altered mental
status and guide diagnostic workup.
Formulate a broad differential diagnosis for acute confusion in a
middle-aged adult, prioritizing life-threatening conditions (e.g.,
stroke, hypoglycemia, sepsis) using clinical findings and risk
stratification.
Select and interpret appropriate diagnostic tests (imaging and
labs) to confirm the diagnosis, rule out serious conditions, and
guide acute management in the ED.
Develop an evidence-based, patient-centered management plan
to stabilize the patient, address the underlying cause, and plan for
, follow-up care, incorporating family support and psychosocial
considerations.
The case emphasizes rapid assessment and prioritization of life-
threatening causes of acute confusion in a 55-year-old female,
leveraging the ED’s full imaging and laboratory capabilities to
ensure timely diagnosis and treatment. Psychosocial impacts (e.g.,
family distress) and patient safety are addressed to support
recovery.
Case Details
History of Present Illness (HPI)Sarah Thompson, a 55-year-old female,
was brought to the ED by her husband with a chief complaint of acute
confusion for 6 hours. Due to the patient’s altered mental status,
history is primarily obtained from her husband, with limited input from
the patient. The following details were gathered: